Re: turmeric/curcumin

[Guest guest]

Hi Thinman:

Thanks for that stuff on curcumin. But I'm not sure I'd go for the

curcumin/curry/India story. There is very little prostate cancer in

Japan, and as far as I know they are not famous for their curry

consumption. India, China and Japan do, however, have low prostate

cancer incidence and substantial white rice consumption in common.

So perhaps we should be loading up on white rice?

Just joking about the white rice. But do you see my point?

I have also seen a number of laudatory pieces on curcumin, which some

time ago caused me to put it on my 'anti-prostate cancer list'.

Checking that list now I see I crossed it off when I read one

critical item. I don't remember the details. But the negative one

was certainly not enough for me to put it on my 'avoid list'.

Certainly there is something in the far east that is a major help in

protecting against prostate cancer. It will be wonderful when

someone finally figures out what it is. Perhaps it WILL turn out to

be curcumin?

Rodney.

--- In , " thin_man02 " <thin_man02@y...>

wrote:

>

> Has anyone been following research on curcumin (a major component

of

> turmeric) as a chemopreventive and anticancer agent? There're

quite a few

> abstracts on curcumin/turmeric on medline. Apparently, certain

cancers such

> as prostate cancer have a comparatively low incidence in curry-

consuming

> nations such as India. I've been sprinkling a little turmeric in

V8 juice and

> tomato juice. With a few drops of tabasco or other hot sauce, it's

actually quite

> good.

>

> --Thin Man

>

> Constitutive activation of transcription factor AP-1 in cervical

cancer and

> suppression of human papillomavirus (HPV) transcription and AP-1

activity in

> HeLa cells by curcumin.

> Int J Cancer. 2004 Oct 28 [Epub ahead of print]

>

> Curcumin inhibits mitogen stimulated lymphocyte proliferation,

NFkappaB

> activation, and IL-2 signaling.

> J Surg Res. 2004 Oct;121(2):171-177.

> PMID: 15501456 [PubMed - as supplied by publisher]

>

> Gafner S, Lee SK, Cuendet M, Barthelemy S, Vergnes L, Labidalle S,

Mehta

> RG, Boone CW, Pezzuto JM. Related Articles, Links

> Biologic evaluation of curcumin and structural derivatives in

cancer

> chemoprevention model systems.

> Phytochemistry. 2004 Nov;65(21):2849-2859.

> PMID: 15501252 [PubMed - as supplied by publisher]

>

> Shenouda NS, Zhou C, Browning JD, Ansell PJ, Sakla MS, Lubahn DB,

> Macdonald RS. Related Articles, Links

> Phytoestrogens in common herbs regulate prostate cancer cell growth

in vitro.

> Nutr Cancer. 2004;49(2):200-8.

> PMID: 15489213 [PubMed - in process]