Re: Can Being Fit Outweigh Fat?

[Guest guest]

What's his age? What's his lifespan estimate?

There is today and tomorrow on PBSyou ch 377, shows on

nutrition.

Looks like a continuing series, included article on aging.

Regards.

----- Original Message -----

From: " Francesca Skelton " <fskelton@...>

" support group " < >

Sent: Friday, November 26, 2004 10:45 AM

Subject: [ ] Can Being Fit Outweigh Fat?

>

> By Rob Stein

>

> At 5-foot-4 and 190 pounds, Jude Mathews would seem to

personify the

> health crisis facing a nation in the throes of an obesity

epidemic. But the

> librarian from ton, Ill., begs to differ.

>

> " My blood pressure is rock solid. My cholesterol numbers

are basically

> fine. My doctors don't see anything they say I need to

worry about, " said

> Mathews, who is 55, exercises regularly and eats a

well-balanced diet. " One

> little number on the scale is not all there is to your

health. "

>

> As medical authorities have become increasingly alarmed

by the rapidly

> rising number of Americans who are overweight and obese,

people such as

> Mathews find themselves at the center of an intense

debate: Can people be

> overweight but still healthy?

>

> In books, in medical journals and at public health

conferences, scientists

> have been dueling over the relative importance of fatness

vs. fitness, and

> whether there is any common ground between the two camps.

A small but vocal

> cadre of researchers has been challenging conventional

wisdom, arguing that

> not only is it possible to be both fat and fit, but

fitness is actually more

> important for health.

>

> " All too often, medical professionals say it's the

obesity we have to cure.

> That's the be-all and end-all. It's not, " said N.

Blair, who heads

> the Institute, a Dallas research foundation focused

on physical

> activity. " The impression is that everyone who is

overweight faces an

> elevated risk for mortality. That's simply not true. "

>

> Other experts, however, maintain that while there may be

exceptions, the

> evidence is clear for most people: Being overweight

significantly increases

> the risk of a host of debilitating and often deadly health

problems,

> including heart attacks, strokes, cancer and diabetes.

>

> " Being overweight has a clear association with important

health problems,

> and even modest weight loss has important health

benefits, " said Walter

> Willett, an expert on nutrition and health at the Harvard

School of Public

> Health. " To tell people it doesn't matter is really

misleading. It does make

> a difference. It makes a huge difference. "

>

> Playing down the risks of excess weight is dangerous,

Willett and others

> say, particularly with two-thirds of Americans already

overweight, including

> one-third who are officially obese.

>

> " I would not want to switch the emphasis away from trying

to control

> weight, " said Lawrence J. Cheskin, director of the s

Hopkins Weight

> Management Center. " That's a clear risk factor. "

>

> Blair and other fitness proponents acknowledge that some

overweight people

> are at increased risk for health problems, and that many

people may benefit

> from losing weight. But they argue that society focuses

far too much on

> dropping pounds and far too little on exercise, eating

well and being

> physically fit.

>

> " I don't believe height and weight is a good indication

of health, " said

> Joanne Ikeda, co-director of the Center for Weight and

Health at the

> University of California at Berkeley. " If a fat person or

obese person has

> normal blood pressure, if their total cholesterol and

glucose levels are

> normal and they are healthy, there is no reason they

should necessarily have

> to lose weight. "

>

> Many people are simply born to be bigger, which does not

necessarily mean

> they are destined to have health problems because of their

weight,

> especially if they exercise regularly and eat well, she

said.

>

> " There is a subset of people who are meant to be large pe

ople, " Ikeda said.

> " If they are in fact 'obese' but they are metabolically

healthy, their

> bodies are constructed in a way that carrying a large

amount of weight is

> not deleterious. "

>

> The increased health risks blamed on being overweight are

really the result

> of many overweight people being out of shape and having

poor diets and other

> unhealthful habits, Blair and others say. If those factors

are considered,

> studies have found that any increased risk virtually

disappears, they say.

>

> " We've studied this from many perspectives in women and

in men and we get

> the same answer: It's not the obesity -- it's the

fitness, " Blair said.

> " Fitness can substantially reduce, if not eliminate, the

high risk of being

> obese. "

>

> Ikeda tests people to see if they are " metabolically

healthy. " If she spots

> warning signs, she recommends exercise and a nutritious

diet, but with the

> goal of making people fitter, not necessarily thinner.

>

> " What weight-loss programs promote are diets that are so

low in calories

> that people are constantly fatigued, and then they have a

hard time getting

> out there to exercise, which is really what will help

them, " Ikeda said.

> " How stupid is that? "

>

> The focus on weight loss is especially misguided because

most people simply

> are unable to lose substantial weight and keep it off,

Ikeda, Blair and

> others say.

>

> " I'm a short, fat guy myself, " Blair said. " I'd like to

be thinner. I'm not

> saying people shouldn't try to lose weight. But we're not

getting anywhere

> with all the focus on obesity -- shouting from the

rooftops how bad obesity

> is. So if the strategy is not working, it seems to me we

ought to be

> thinking about different strategies. "

>

> Becoming fit is often much more attainable, Blair and

others say.

>

> " If you take a fat person who has all these health

problems that have been

> labeled weight-related health problems and put them on an

exercise program

> and clean up their diet, their health generally improves

yet their body

> weight hasn't budged much, " said Glenn A. Gaesser, a

University of Virginia

> physiologist who wrote " Big Fat Lies: The Truth About Your

Weight and Your

> Health, " a book that questions many assumptions about

obesity. " It's far

> easier to get a fat person fit than to get a fat person

thin. "

>

> Mathews, the Illinois librarian, takes dance, Pilates and

tai chi classes

> several nights a week and lifts weights to stay fit, and

watches what she

> eats to stay healthy.

>

> " I wouldn't mind losing weight, but I know if I go on a

weight-loss diet

> I'll just spring right back, " Mathews said. " What is

really dangerous is

> yo-yo dieting, not to mention destroying people's

self-esteem. "

>

> The obsession with weight also risks prompting people to

overreact, some

> say.

>

> " We have yuppie parents putting their kids on diets just

because they gain

> a few pounds, " Ikeda said. " We see adolescent girls

obsessed with obtaining

> the so-called ideal body image. We see people smoking,

abusing laxatives and

> taking all sorts of extreme measures. "

>

> Another danger is that the emphasis on weight may be

misleading thin people

> about their health.

>

> " If someone is in what is considered the normal range,

they think they

> don't have to exercise and can eat whatever they want, "

Gaesser said.

>

> Willett and others acknowledge that fitness is important

and that

> overweight people benefit from exercise and eating better

even without

> losing weight. But they argue that a careful analysis of

many large studies

> has shown a clear, independent relationship between excess

weight and

> increased risk for health problems.

>

> " When you look at the data carefully, you find that

people who are active

> and lean have the lowest mortality of all, " Willett said.

>

> And many obesity researchers take issue with the

contention that most

> overweight people cannot lose weight.

>

> " People can lose weight. They do lose weight, " said

Arthur , a weight

> expert at Washington University. " I've seen people

who are indolent

> in their health habits and they lose weight and their

blood pressure comes

> down and their cholesterol comes down and they feel

wonderful, even without

> doing any exercise. "

>

> Willett is also concerned that turning the focus away

from weight will keep

> people from being vigilant about preventing weight gain in

the first place,

> which is the most effective strategy.

>

> " One of the big problems is by the time people become

overweight or obese

> it's very hard for them to become active. They've

developed arthritis or

> other problems that makes it hard, which is why we have to

pay attention to

> weight early on, " Willett said.

>

> Despite the intensity of the debate, Willett, ,

Blair, Gaesser and

> others have been trying to find common ground, with each

side emphasizing

> that the two ideas are not necessarily mutually exclusive.

The best strategy

> would be to encourage people to exercise regularly and eat

well. Some will

> lose weight, some won't, but all will benefit from getting

as much exercise

> as possible and becoming more physically fit and possibly

trimming down in

> the process.

>

> " This is something that really shouldn't be a debate of

one versus the

> other, " Willett said. " It's clear that both fitness and

fatness are

> important. It's definitely good to be as fit as possible

no matter what your

> body weight. But it's also clear that it is optimum to be

both lean and fit.

> It shouldn't be a question of one or the other. "

>

[Guest guest]

There are two things that happen that are interesting.

1) people seem to add fat with age.

2) people seem to lose muscle with age.

It seems to me the two are related in a complex manner. I

deduced logically, that excess calories lead to the

production of fat that has to be stored somewhere and

possibly some of it invades the muscle cells and restricts

flow of nutrients and wastes in/out of the cell.

The lessened circulation may cause mitochondria to die and

the cell's function turns to a fat cell.

Just musing.

Regards.

[Guest guest]

Hi folks:

Good to bear in mind that, imo, the Institute is not exactly

what one would call an 'independent, bias-free' organization, when it

comes to matters of exercise.

Rodney.

> By Rob Stein

>

> At 5-foot-4 and 190 pounds, Jude Mathews would seem to personify

the

> health crisis facing a nation in the throes of an obesity epidemic.

But the

> librarian from ton, Ill., begs to differ.

>

> " My blood pressure is rock solid. My cholesterol numbers are

basically

> fine. My doctors don't see anything they say I need to worry

about, " said

> Mathews, who is 55, exercises regularly and eats a well-balanced

diet. " One

> little number on the scale is not all there is to your health. "

>

> As medical authorities have become increasingly alarmed by the

rapidly

> rising number of Americans who are overweight and obese, people

such as

> Mathews find themselves at the center of an intense debate: Can

people be

> overweight but still healthy?

>

> In books, in medical journals and at public health conferences,

scientists

> have been dueling over the relative importance of fatness vs.

fitness, and

> whether there is any common ground between the two camps. A small

but vocal

> cadre of researchers has been challenging conventional wisdom,

arguing that

> not only is it possible to be both fat and fit, but fitness is

actually more

> important for health.

>

> " All too often, medical professionals say it's the obesity we have

to cure.

> That's the be-all and end-all. It's not, " said N. Blair, who

heads

> the Institute, a Dallas research foundation focused on

physical

> activity. " The impression is that everyone who is overweight faces

an

> elevated risk for mortality. That's simply not true. "

>

> Other experts, however, maintain that while there may be

exceptions, the

> evidence is clear for most people: Being overweight significantly

increases

> the risk of a host of debilitating and often deadly health problems,

> including heart attacks, strokes, cancer and diabetes.

>

> " Being overweight has a clear association with important health

problems,

> and even modest weight loss has important health benefits, " said

Walter

> Willett, an expert on nutrition and health at the Harvard School of

Public

> Health. " To tell people it doesn't matter is really misleading. It

does make

> a difference. It makes a huge difference. "

>

> Playing down the risks of excess weight is dangerous, Willett and

others

> say, particularly with two-thirds of Americans already overweight,

including

> one-third who are officially obese.

>

> " I would not want to switch the emphasis away from trying to

control

> weight, " said Lawrence J. Cheskin, director of the s Hopkins

Weight

> Management Center. " That's a clear risk factor. "

>

> Blair and other fitness proponents acknowledge that some

overweight people

> are at increased risk for health problems, and that many people may

benefit

> from losing weight. But they argue that society focuses far too

much on

> dropping pounds and far too little on exercise, eating well and

being

> physically fit.

>

> " I don't believe height and weight is a good indication of

health, " said

> Joanne Ikeda, co-director of the Center for Weight and Health at the

> University of California at Berkeley. " If a fat person or obese

person has

> normal blood pressure, if their total cholesterol and glucose

levels are

> normal and they are healthy, there is no reason they should

necessarily have

> to lose weight. "

>

> Many people are simply born to be bigger, which does not

necessarily mean

> they are destined to have health problems because of their weight,

> especially if they exercise regularly and eat well, she said.

>

> " There is a subset of people who are meant to be large people, "

Ikeda said.

> " If they are in fact 'obese' but they are metabolically healthy,

their

> bodies are constructed in a way that carrying a large amount of

weight is

> not deleterious. "

>

> The increased health risks blamed on being overweight are really

the result

> of many overweight people being out of shape and having poor diets

and other

> unhealthful habits, Blair and others say. If those factors are

considered,

> studies have found that any increased risk virtually disappears,

they say.

>

> " We've studied this from many perspectives in women and in men and

we get

> the same answer: It's not the obesity -- it's the fitness, " Blair

said.

> " Fitness can substantially reduce, if not eliminate, the high risk

of being

> obese. "

>

> Ikeda tests people to see if they are " metabolically healthy. " If

she spots

> warning signs, she recommends exercise and a nutritious diet, but

with the

> goal of making people fitter, not necessarily thinner.

>

> " What weight-loss programs promote are diets that are so low in

calories

> that people are constantly fatigued, and then they have a hard time

getting

> out there to exercise, which is really what will help them, " Ikeda

said.

> " How stupid is that? "

>

> The focus on weight loss is especially misguided because most

people simply

> are unable to lose substantial weight and keep it off, Ikeda, Blair

and

> others say.

>

> " I'm a short, fat guy myself, " Blair said. " I'd like to be

thinner. I'm not

> saying people shouldn't try to lose weight. But we're not getting

anywhere

> with all the focus on obesity -- shouting from the rooftops how bad

obesity

> is. So if the strategy is not working, it seems to me we ought to be

> thinking about different strategies. "

>

> Becoming fit is often much more attainable, Blair and others say.

>

> " If you take a fat person who has all these health problems that

have been

> labeled weight-related health problems and put them on an exercise

program

> and clean up their diet, their health generally improves yet their

body

> weight hasn't budged much, " said Glenn A. Gaesser, a University of

Virginia

> physiologist who wrote " Big Fat Lies: The Truth About Your Weight

and Your

> Health, " a book that questions many assumptions about

obesity. " It's far

> easier to get a fat person fit than to get a fat person thin. "

>

> Mathews, the Illinois librarian, takes dance, Pilates and tai chi

classes

> several nights a week and lifts weights to stay fit, and watches

what she

> eats to stay healthy.

>

> " I wouldn't mind losing weight, but I know if I go on a weight-

loss diet

> I'll just spring right back, " Mathews said. " What is really

dangerous is

> yo-yo dieting, not to mention destroying people's self-esteem. "

>

> The obsession with weight also risks prompting people to

overreact, some

> say.

>

> " We have yuppie parents putting their kids on diets just because

they gain

> a few pounds, " Ikeda said. " We see adolescent girls obsessed with

obtaining

> the so-called ideal body image. We see people smoking, abusing

laxatives and

> taking all sorts of extreme measures. "

>

> Another danger is that the emphasis on weight may be misleading

thin people

> about their health.

>

> " If someone is in what is considered the normal range, they think

they

> don't have to exercise and can eat whatever they want, " Gaesser

said.

>

> Willett and others acknowledge that fitness is important and that

> overweight people benefit from exercise and eating better even

without

> losing weight. But they argue that a careful analysis of many large

studies

> has shown a clear, independent relationship between excess weight

and

> increased risk for health problems.

>

> " When you look at the data carefully, you find that people who are

active

> and lean have the lowest mortality of all, " Willett said.

>

> And many obesity researchers take issue with the contention that

most

> overweight people cannot lose weight.

>

> " People can lose weight. They do lose weight, " said Arthur ,

a weight

> expert at Washington University. " I've seen people who are

indolent

> in their health habits and they lose weight and their blood

pressure comes

> down and their cholesterol comes down and they feel wonderful, even

without

> doing any exercise. "

>

> Willett is also concerned that turning the focus away from weight

will keep

> people from being vigilant about preventing weight gain in the

first place,

> which is the most effective strategy.

>

> " One of the big problems is by the time people become overweight

or obese

> it's very hard for them to become active. They've developed

arthritis or

> other problems that makes it hard, which is why we have to pay

attention to

> weight early on, " Willett said.

>

> Despite the intensity of the debate, Willett, , Blair,

Gaesser and

> others have been trying to find common ground, with each side

emphasizing

> that the two ideas are not necessarily mutually exclusive. The best

strategy

> would be to encourage people to exercise regularly and eat well.

Some will

> lose weight, some won't, but all will benefit from getting as much

exercise

> as possible and becoming more physically fit and possibly trimming

down in

> the process.

>

> " This is something that really shouldn't be a debate of one versus

the

> other, " Willett said. " It's clear that both fitness and fatness are

> important. It's definitely good to be as fit as possible no matter

what your

> body weight. But it's also clear that it is optimum to be both lean

and fit.

> It shouldn't be a question of one or the other. "

[Guest guest]

I believe the mechanism is simpler than that. As we age we generate less

growth hormone. This decline leads to a subsequent decline in lean body mass

as less growth hormone generates less muscle growth for similar diet and

activity level. Just recall how easy it was to build muscle in our youth as

compared to now. Since our energy intake is typically habitual and roughly

constant, less LBM will burn less calories resulting in an energy surplus

which gets stored as adipose.

FWIW some older individuals who brag about being the same weight as they

were in high school have in fact lost significant LBM to remodeling in the

lower GH environment. Their fat is not excessive and often ends up embedded

in musculature (marbling?).

I feel that attention to this phenomenon suggests resistance training and

other interventions can somewhat mitigate at least that one effect of aging.

A second mechanism that is less clear (to me) is my perception that we have

lower levels of some nervous system chemicals (?) that facilitate muscular

signaling, perhaps making similar amounts of muscle mass less effective.

JR

-----Original Message-----

From: jwwright [mailto:jwwright@...]

Sent: Friday, November 26, 2004 11:16 AM

Subject: Re: [ ] Can Being Fit Outweigh Fat?

There are two things that happen that are interesting.

1) people seem to add fat with age.

2) people seem to lose muscle with age.

It seems to me the two are related in a complex manner. I

deduced logically, that excess calories lead to the

production of fat that has to be stored somewhere and

possibly some of it invades the muscle cells and restricts

flow of nutrients and wastes in/out of the cell.

The lessened circulation may cause mitochondria to die and

the cell's function turns to a fat cell.

Just musing.

Regards.

[Guest guest]

The growth hormone is a clue, but people who do manual labor who get plenty of exercise, decline in muscle. It wasn't that I gave up exercising, it was that I got fat and slowed up. I was in "good shape" when that change began.

Almost suddenly, I couldn't run up 6 flights to the 4th floor in bldg one. I got to the top and I was a little short of breath. Gradually it got worse. Was it that I finally reached a point where athero in the coronaries began to restrict the blood flow - no, I dont have such (by angiogram). Was it hypertension - no, it preceded the HTN by 6 years, at least. Was it a diet change - no, I ate the same food for many years.

Hypothesizing, maybe it was that muscle tissue didnt get replaced as fast as in previous years due to some hormone.

Now how does that actually take place? The muscle I'm using gets worn somehow, and the body replaces it with new tissue. Old protein gets recycled into new cells with new mitochondria? OR does the cell gets glycated into aged tissue?

But it would fat cells should get glycated too. Their walls contain protein and they should be deaminated the same way as any other cell.

Regards.

----- Original Message -----

From:

Sent: Friday, November 26, 2004 11:42 AM

Subject: RE: [ ] Can Being Fit Outweigh Fat?

I believe the mechanism is simpler than that. As we age we generate lessgrowth hormone. This decline leads to a subsequent decline in lean body massas less growth hormone generates less muscle growth for similar diet andactivity level. Just recall how easy it was to build muscle in our youth ascompared to now. Since our energy intake is typically habitual and roughlyconstant, less LBM will burn less calories resulting in an energy surpluswhich gets stored as adipose.FWIW some older individuals who brag about being the same weight as theywere in high school have in fact lost significant LBM to remodeling in thelower GH environment. Their fat is not excessive and often ends up embeddedin musculature (marbling?).I feel that attention to this phenomenon suggests resistance training andother interventions can somewhat mitigate at least that one effect of aging.A second mechanism that is less clear (to me) is my perception that we havelower levels of some nervous system chemicals (?) that facilitate muscularsignaling, perhaps making similar amounts of muscle mass less effective. JR-----Original Message-----From: jwwright [mailto:jwwright@...]Sent: Friday, November 26, 2004 11:16 AM Subject: Re: [ ] Can Being Fit Outweigh Fat?There are two things that happen that are interesting.1) people seem to add fat with age.2) people seem to lose muscle with age.It seems to me the two are related in a complex manner. Ideduced logically, that excess calories lead to theproduction of fat that has to be stored somewhere andpossibly some of it invades the muscle cells and restrictsflow of nutrients and wastes in/out of the cell.The lessened circulation may cause mitochondria to die andthe cell's function turns to a fat cell.Just musing.Regards.

[Guest guest]

What I'm saying is along the lines of you have to run faster to stay in the same place. The same diet and same activity level combined with lower GH will result in less muscle. Less muscle means less calories burned at rest (and probably working too). If you eat the same with less muscles you will have a different energy balance. Getting old isn't for wimps. :-)

JR

-----Original Message-----From: jwwright [mailto:jwwright@...]Sent: Friday, November 26, 2004 12:33 PM Subject: Re: [ ] Can Being Fit Outweigh Fat?

The growth hormone is a clue, but people who do manual labor who get plenty of exercise, decline in muscle. It wasn't that I gave up exercising, it was that I got fat and slowed up. I was in "good shape" when that change began.

Almost suddenly, I couldn't run up 6 flights to the 4th floor in bldg one. I got to the top and I was a little short of breath. Gradually it got worse. Was it that I finally reached a point where athero in the coronaries began to restrict the blood flow - no, I dont have such (by angiogram). Was it hypertension - no, it preceded the HTN by 6 years, at least. Was it a diet change - no, I ate the same food for many years.

Hypothesizing, maybe it was that muscle tissue didnt get replaced as fast as in previous years due to some hormone.

Now how does that actually take place? The muscle I'm using gets worn somehow, and the body replaces it with new tissue. Old protein gets recycled into new cells with new mitochondria? OR does the cell gets glycated into aged tissue?

But it would fat cells should get glycated too. Their walls contain protein and they should be deaminated the same way as any other cell.

Regards.

----- Original Message -----

From:

Sent: Friday, November 26, 2004 11:42 AM

Subject: RE: [ ] Can Being Fit Outweigh Fat?

I believe the mechanism is simpler than that. As we age we generate lessgrowth hormone. This decline leads to a subsequent decline in lean body massas less growth hormone generates less muscle growth for similar diet andactivity level. Just recall how easy it was to build muscle in our youth ascompared to now. Since our energy intake is typically habitual and roughlyconstant, less LBM will burn less calories resulting in an energy surpluswhich gets stored as adipose.FWIW some older individuals who brag about being the same weight as theywere in high school have in fact lost significant LBM to remodeling in thelower GH environment. Their fat is not excessive and often ends up embeddedin musculature (marbling?).I feel that attention to this phenomenon suggests resistance training andother interventions can somewhat mitigate at least that one effect of aging.A second mechanism that is less clear (to me) is my perception that we havelower levels of some nervous system chemicals (?) that facilitate muscularsignaling, perhaps making similar amounts of muscle mass less effective. JR-----Original Message-----From: jwwright [mailto:jwwright@...]Sent: Friday, November 26, 2004 11:16 AM Subject: Re: [ ] Can Being Fit Outweigh Fat?There are two things that happen that are interesting.1) people seem to add fat with age.2) people seem to lose muscle with age.It seems to me the two are related in a complex manner. Ideduced logically, that excess calories lead to theproduction of fat that has to be stored somewhere andpossibly some of it invades the muscle cells and restrictsflow of nutrients and wastes in/out of the cell.The lessened circulation may cause mitochondria to die andthe cell's function turns to a fat cell.Just musing.Regards.

[Guest guest]

You got that right, another ex-coworker bit the dust at 67yo. He had a lot of stress.

We have to balance a lot of things.

Regards.

----- Original Message -----

From:

Sent: Friday, November 26, 2004 1:32 PM

Subject: RE: [ ] Can Being Fit Outweigh Fat?

What I'm saying is along the lines of you have to run faster to stay in the same place. The same diet and same activity level combined with lower GH will result in less muscle. Less muscle means less calories burned at rest (and probably working too). If you eat the same with less muscles you will have a different energy balance. Getting old isn't for wimps. :-)

JR

-----Original Message-----From: jwwright [mailto:jwwright@...]Sent: Friday, November 26, 2004 12:33 PM Subject: Re: [ ] Can Being Fit Outweigh Fat?

The growth hormone is a clue, but people who do manual labor who get plenty of exercise, decline in muscle. It wasn't that I gave up exercising, it was that I got fat and slowed up. I was in "good shape" when that change began.

Almost suddenly, I couldn't run up 6 flights to the 4th floor in bldg one. I got to the top and I was a little short of breath. Gradually it got worse. Was it that I finally reached a point where athero in the coronaries began to restrict the blood flow - no, I dont have such (by angiogram). Was it hypertension - no, it preceded the HTN by 6 years, at least. Was it a diet change - no, I ate the same food for many years.

Hypothesizing, maybe it was that muscle tissue didnt get replaced as fast as in previous years due to some hormone.

Now how does that actually take place? The muscle I'm using gets worn somehow, and the body replaces it with new tissue. Old protein gets recycled into new cells with new mitochondria? OR does the cell gets glycated into aged tissue?

But it would fat cells should get glycated too. Their walls contain protein and they should be deaminated the same way as any other cell.

Regards.