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Re: Pt 2: How To Live To be A 100

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Oddly, I have found I can " control " HDL, although, whether this is of

any clinical benefit is unclear. Over the past years, my HDL has

ranged from 55 mg/dl to 105 mg/dl, depending upon my diet, exercise,

supplements.

On Thu, 13 Jan 2005 11:16:37 -0500, Jeff Novick <jnovick@...> wrote:

>

> The following are mostly about lipids and diet. FYI, his talk was

> immediately after my presentation. Part of my discussion was about the

> specifics about the Mediterranean diet and the studies surrounding it,

> giving actual analysis and composition info on their intake in the differing

> regions and how it is changed over the years.

>

>

> 13) Total Cholesterol: Keep it below 200. He said 180 was better but at

> least under 200

>

> 14) HDL: Above 45. He said as there is little one can do about HDL to

> influence it, most of the focus should be on Total Cholesterol, and LDL. He

> also said not to be misled by a high HDL and not all HDL is good for you as

> some of the subfractions are not good.

>

> 15) LDL : Below 100. High Risk patients should keep it under 80, under 65

> is even better. He though everyone, should be on some dose of a statin to

> acheive this is neccessary.

>

> He also said he was good friends with Dr Castelli and recommended his latest

> book on lipids.

>

> 16) Triglycerides: Below 100

>

> 17) Be Skinny : Obesity Kills (this is where he made the comment about the

> Wacko Cronnies).

>

> 18) Mediterranean Diet. Before he gave the info he said he agreed with my

> talk and the points i made except for one area, which he said, I missed,

> and that was about the Lyons study which compared a Med diet to a low fat

> diet and how much better the Med diet did so he had some questions about

> lower fat diets. Afterward his presentaiton, we talked, and I showed him

> my slides on the Lyons Study and that I didnt miss it, I just ran out of

> time. The lyons study has been misrepresented in the news. The Med diet,

> actually had less total fat, less sat fat, less choleseterol. less calories

> and more fiber than the supposed " low fat " diet. So, if he was favoring

> the diet intervention that produced the best results, it was the lower fat,

> lower calorie, higher fiber diet, regardless of what the media said. :)

>

> 18A: Olive oil: or canola oil. Avoid other vegetable oil, butter, and

> margarine

> 18B: Fish: Salmon, Cod and anchovies

> 18C: Nuts: Walnuts and flaxseeds

> 18D: Veggies and Fruits: Especially root veggies, tomatoes and blueberries

> 18E:Drink Alcohol: Any kind, one or two drinks a day. If you are an

> alcoholic, than drink grape juice.

>

> 19: Yearly Physicals. You cant control what you dont know

> 20: Control Blood Pressure: With Lifestyle choices first, than medication if

> needed. Aim for <120/<80

> 21: Mammograms: Annually if you are over 40

> 22: PSA: A must for men over 40.

> 23: Colon Cancer Screening: Worth the hassle, start at age 50

> 24: Stress tests: Annually,

>

> Last part coming soon.

>

> ________________________________

>

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Root veggies (like white potato???)

What of almonds, other tree nuts?

Sesame seeds?

Herring?

Citrus?

On Thu, 13 Jan 2005 13:02:54 -0500, Dowling

<christopher.a.dowling@...> wrote:

> Oddly, I have found I can " control " HDL, although, whether this is of

> any clinical benefit is unclear. Over the past years, my HDL has

> ranged from 55 mg/dl to 105 mg/dl, depending upon my diet, exercise,

> supplements.

>

>

> On Thu, 13 Jan 2005 11:16:37 -0500, Jeff Novick <jnovick@...> wrote:

> >

> > The following are mostly about lipids and diet. FYI, his talk was

> > immediately after my presentation. Part of my discussion was about the

> > specifics about the Mediterranean diet and the studies surrounding it,

> > giving actual analysis and composition info on their intake in the differing

> > regions and how it is changed over the years.

> >

> >

> > 13) Total Cholesterol: Keep it below 200. He said 180 was better but at

> > least under 200

> >

> > 14) HDL: Above 45. He said as there is little one can do about HDL to

> > influence it, most of the focus should be on Total Cholesterol, and LDL. He

> > also said not to be misled by a high HDL and not all HDL is good for you as

> > some of the subfractions are not good.

> >

> > 15) LDL : Below 100. High Risk patients should keep it under 80, under 65

> > is even better. He though everyone, should be on some dose of a statin to

> > acheive this is neccessary.

> >

> > He also said he was good friends with Dr Castelli and recommended his latest

> > book on lipids.

> >

> > 16) Triglycerides: Below 100

> >

> > 17) Be Skinny : Obesity Kills (this is where he made the comment about the

> > Wacko Cronnies).

> >

> > 18) Mediterranean Diet. Before he gave the info he said he agreed with my

> > talk and the points i made except for one area, which he said, I missed,

> > and that was about the Lyons study which compared a Med diet to a low fat

> > diet and how much better the Med diet did so he had some questions about

> > lower fat diets. Afterward his presentaiton, we talked, and I showed him

> > my slides on the Lyons Study and that I didnt miss it, I just ran out of

> > time. The lyons study has been misrepresented in the news. The Med diet,

> > actually had less total fat, less sat fat, less choleseterol. less calories

> > and more fiber than the supposed " low fat " diet. So, if he was favoring

> > the diet intervention that produced the best results, it was the lower fat,

> > lower calorie, higher fiber diet, regardless of what the media said. :)

> >

> > 18A: Olive oil: or canola oil. Avoid other vegetable oil, butter, and

> > margarine

> > 18B: Fish: Salmon, Cod and anchovies

> > 18C: Nuts: Walnuts and flaxseeds

> > 18D: Veggies and Fruits: Especially root veggies, tomatoes and blueberries

> > 18E:Drink Alcohol: Any kind, one or two drinks a day. If you are an

> > alcoholic, than drink grape juice.

> >

> > 19: Yearly Physicals. You cant control what you dont know

> > 20: Control Blood Pressure: With Lifestyle choices first, than medication if

> > needed. Aim for <120/<80

> > 21: Mammograms: Annually if you are over 40

> > 22: PSA: A must for men over 40.

> > 23: Colon Cancer Screening: Worth the hassle, start at age 50

> > 24: Stress tests: Annually,

> >

> > Last part coming soon.

> >

> > ________________________________

> >

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Hi:

What about brazil nuts? Tea? GREEN VEGETABLES??? Onions,

especially green onions? Mushrooms, especially 'brown mushrooms'?

Rodney.

> > Oddly, I have found I can " control " HDL, although, whether this

is of

> > any clinical benefit is unclear. Over the past years, my HDL has

> > ranged from 55 mg/dl to 105 mg/dl, depending upon my diet,

exercise,

> > supplements.

> >

> >

> > On Thu, 13 Jan 2005 11:16:37 -0500, Jeff Novick <jnovick@p...>

wrote:

> > >

> > > The following are mostly about lipids and diet. FYI, his talk

was

> > > immediately after my presentation. Part of my discussion was

about the

> > > specifics about the Mediterranean diet and the studies

surrounding it,

> > > giving actual analysis and composition info on their intake in

the differing

> > > regions and how it is changed over the years.

> > >

> > >

> > > 13) Total Cholesterol: Keep it below 200. He said 180 was

better but at

> > > least under 200

> > >

> > > 14) HDL: Above 45. He said as there is little one can do

about HDL to

> > > influence it, most of the focus should be on Total Cholesterol,

and LDL. He

> > > also said not to be misled by a high HDL and not all HDL is

good for you as

> > > some of the subfractions are not good.

> > >

> > > 15) LDL : Below 100. High Risk patients should keep it under

80, under 65

> > > is even better. He though everyone, should be on some dose of

a statin to

> > > acheive this is neccessary.

> > >

> > > He also said he was good friends with Dr Castelli and

recommended his latest

> > > book on lipids.

> > >

> > > 16) Triglycerides: Below 100

> > >

> > > 17) Be Skinny : Obesity Kills (this is where he made the

comment about the

> > > Wacko Cronnies).

> > >

> > > 18) Mediterranean Diet. Before he gave the info he said he

agreed with my

> > > talk and the points i made except for one area, which he said,

I missed,

> > > and that was about the Lyons study which compared a Med diet to

a low fat

> > > diet and how much better the Med diet did so he had some

questions about

> > > lower fat diets. Afterward his presentaiton, we talked, and I

showed him

> > > my slides on the Lyons Study and that I didnt miss it, I just

ran out of

> > > time. The lyons study has been misrepresented in the news.

The Med diet,

> > > actually had less total fat, less sat fat, less choleseterol.

less calories

> > > and more fiber than the supposed " low fat " diet. So, if he

was favoring

> > > the diet intervention that produced the best results, it was

the lower fat,

> > > lower calorie, higher fiber diet, regardless of what the media

said. :)

> > >

> > > 18A: Olive oil: or canola oil. Avoid other vegetable oil,

butter, and

> > > margarine

> > > 18B: Fish: Salmon, Cod and anchovies

> > > 18C: Nuts: Walnuts and flaxseeds

> > > 18D: Veggies and Fruits: Especially root veggies, tomatoes and

blueberries

> > > 18E:Drink Alcohol: Any kind, one or two drinks a day. If you

are an

> > > alcoholic, than drink grape juice.

> > >

> > > 19: Yearly Physicals. You cant control what you dont know

> > > 20: Control Blood Pressure: With Lifestyle choices first, than

medication if

> > > needed. Aim for <120/<80

> > > 21: Mammograms: Annually if you are over 40

> > > 22: PSA: A must for men over 40.

> > > 23: Colon Cancer Screening: Worth the hassle, start at age 50

> > > 24: Stress tests: Annually,

> > >

> > > Last part coming soon.

> > >

> > > ________________________________

> > >

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Hi :

Please .......... which combination of diet, exercise and

supplements gets your HDL up to 105? (TIA!) I would be ecstatic if

I could get mine up to 55! (Probably too much starch. Trying to fix

that).

Rodney.

> Oddly, I have found I can " control " HDL, although, whether this is

of

> any clinical benefit is unclear. Over the past years, my HDL has

> ranged from 55 mg/dl to 105 mg/dl, depending upon my diet, exercise,

> supplements.

>

>

> On Thu, 13 Jan 2005 11:16:37 -0500, Jeff Novick <jnovick@p...>

wrote:

> >

> > The following are mostly about lipids and diet. FYI, his talk

was

> > immediately after my presentation. Part of my discussion was

about the

> > specifics about the Mediterranean diet and the studies

surrounding it,

> > giving actual analysis and composition info on their intake in

the differing

> > regions and how it is changed over the years.

> >

> >

> > 13) Total Cholesterol: Keep it below 200. He said 180 was better

but at

> > least under 200

> >

> > 14) HDL: Above 45. He said as there is little one can do about

HDL to

> > influence it, most of the focus should be on Total Cholesterol,

and LDL. He

> > also said not to be misled by a high HDL and not all HDL is good

for you as

> > some of the subfractions are not good.

> >

> > 15) LDL : Below 100. High Risk patients should keep it under 80,

under 65

> > is even better. He though everyone, should be on some dose of a

statin to

> > acheive this is neccessary.

> >

> > He also said he was good friends with Dr Castelli and recommended

his latest

> > book on lipids.

> >

> > 16) Triglycerides: Below 100

> >

> > 17) Be Skinny : Obesity Kills (this is where he made the comment

about the

> > Wacko Cronnies).

> >

> > 18) Mediterranean Diet. Before he gave the info he said he

agreed with my

> > talk and the points i made except for one area, which he said, I

missed,

> > and that was about the Lyons study which compared a Med diet to a

low fat

> > diet and how much better the Med diet did so he had some

questions about

> > lower fat diets. Afterward his presentaiton, we talked, and I

showed him

> > my slides on the Lyons Study and that I didnt miss it, I just ran

out of

> > time. The lyons study has been misrepresented in the news. The

Med diet,

> > actually had less total fat, less sat fat, less choleseterol.

less calories

> > and more fiber than the supposed " low fat " diet. So, if he was

favoring

> > the diet intervention that produced the best results, it was the

lower fat,

> > lower calorie, higher fiber diet, regardless of what the media

said. :)

> >

> > 18A: Olive oil: or canola oil. Avoid other vegetable oil,

butter, and

> > margarine

> > 18B: Fish: Salmon, Cod and anchovies

> > 18C: Nuts: Walnuts and flaxseeds

> > 18D: Veggies and Fruits: Especially root veggies, tomatoes and

blueberries

> > 18E:Drink Alcohol: Any kind, one or two drinks a day. If you are

an

> > alcoholic, than drink grape juice.

> >

> > 19: Yearly Physicals. You cant control what you dont know

> > 20: Control Blood Pressure: With Lifestyle choices first, than

medication if

> > needed. Aim for <120/<80

> > 21: Mammograms: Annually if you are over 40

> > 22: PSA: A must for men over 40.

> > 23: Colon Cancer Screening: Worth the hassle, start at age 50

> > 24: Stress tests: Annually,

> >

> > Last part coming soon.

> >

> > ________________________________

> >

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Perhaps we in this group are more up to date than most, even " authorities "

on the subject :-))).

Another example not included is one of Jeff's recent posts about legumes.

IIRC, that was the one major element in all the longest-lived peoples like

Okinawans, Mediterranean peoples etc.

on 1/13/2005 1:24 PM, Rodney at perspect1111@... wrote:

>

> Hi:

>

> What about brazil nuts? Tea? GREEN VEGETABLES??? Onions,

> especially green onions? Mushrooms, especially 'brown mushrooms'?

>

> Rodney.

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AFAIK exercise and alcohol both increase HDL, but as noted there is some debate,

as there are several sub fractions of HDL.... There

does seem to be a positive health correlation with moderate alcohol consumption

for many so this (HDL) may or may not be " a " factor.

Once again targets and guidelines for overweight AL eaters may not perfectly

apply to CR.

JR

PS.. an interesting angle on foods we believe to be above question. Orange

carrots are a recent variation (16th century). Older

carrots that we may have evolved eating were red, blue, and yellow... FWIW

-----Original Message-----

From: Rodney [mailto:perspect1111@...]

Sent: Thursday, January 13, 2005 12:28 PM

Subject: [ ] Re: Pt 2: How To Live To be A 100

Hi :

Please .......... which combination of diet, exercise and

supplements gets your HDL up to 105? (TIA!) I would be ecstatic if

I could get mine up to 55! (Probably too much starch. Trying to fix

that).

Rodney.

--

>

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Delurking to mention that the famous Okinawan sweet potatoes are -

PURPLE, in fact, screaming magenta purple! And potatoes as originally

grown in the Andes came in an astonishing range of colors, some of

which occasionally turn up in the gourmet produce bins. I wonder how

many interesting antioxidents we miss out on nowadays because we have

limited our foods to such a narrow range of preferred hues.

http://tinyurl.com/6aqhe

The Okinawan sweet potato

--- In , " " <crjohnr@b...>

wrote:

> PS.. an interesting angle on foods we believe to be above question.

Orange carrots are a recent variation (16th century). Older

> carrots that we may have evolved eating were red, blue, and

yellow... FWIW

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Unlike some American sweet potatoes that have purple skin and orange

flesh, the Okinawan sweet potato has a cream skin and screaming purple

flesh. A picture is at the link. ( http://tinyurl.com/6aqhe )

Purple generally comes from anthocyanins in berries and other foods,

but I don't know if those are the responsible pigments in the sweet

potatoes.

> Good point.

> I believe the inside is yellow or orange. Do you eat the purple skin?

> I often find the chemicals in the plants in duke's database, but I

can't always find if those chems are beneficial.

> Is purple good?

>

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Thanks,

My first Pubmed search for "anthocyanins and cancer", yields 74 results, the first being:

J Biomed Biotechnol. 2004;2004(5):321-325.

Molecular Mechanisms Behind the Chemopreventive Effects of Anthocyanidins.Hou DX, Fujii M, Terahara N, Yoshimoto M.Anthocyanins are polyphenolic ring-based flavonoids, and are widespread in fruits and vegetables of red-blue color. Epidemiological investigations and animal experiments have indicated that anthocyanins may contribute to cancer chemoprevention. The studies on the mechanism have been done recently at molecular level. This review summarizes current molecular bases for anthocyanidins on several key steps involved in cancer chemoprevention: (i) inhibition of anthocyanidins in cell transformation through targeting mitogen-activated protein kinase (MAPK) pathway and activator protein 1 (AP-1) factor; (ii) suppression of anthocyanidins in inflammation and carcinogenesis through targeting nuclear factor kappa B (NF- $\kappa$ B) pathway and cyclooxygenase 2 (COX-2) gene; (iii) apoptotic induction of cancer cells by anthocyanidins through reactive oxygen species (ROS) / c-Jun NH(2)-terminal kinase (JNK)-mediated caspase activation. These data provide a first molecular view of anthocyanidins contributing to cancer chemoprevention.PMID: 15577196

Regards.

----- Original Message -----

From: karenlruss@...

Sent: Friday, January 14, 2005 8:18 AM

Subject: [ ] Re: Pt 2: How To Live To be A 100

Unlike some American sweet potatoes that have purple skin and orangeflesh, the Okinawan sweet potato has a cream skin and screaming purpleflesh. A picture is at the link. ( http://tinyurl.com/6aqhe ) Purple generally comes from anthocyanins in berries and other foods,but I don't know if those are the responsible pigments in the sweetpotatoes.> Good point.> I believe the inside is yellow or orange. Do you eat the purple skin?> I often find the chemicals in the plants in duke's database, but Ican't always find if those chems are beneficial. > Is purple good?>

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Another tidbit from the same article "Food Colorings" Jan 8 Science News was a comment made in passing about these nutrients acting differently when consumed in foods vs. supplementation as extracts.

That statement resonated with me as we often fall into a more is better, pills are good, etc... mentality.

The good news is there are some scientists who "get it" and are investigating legacy foods for possible benefits.

JR

-----Original Message-----From: jwwright [mailto:jwwright@...]Sent: Friday, January 14, 2005 11:16 AM Subject: Re: [ ] Re: Pt 2: How To Live To be A 100

Thanks,

My first Pubmed search for "anthocyanins and cancer", yields 74 results, the first being:

J Biomed Biotechnol. 2004;2004(5):321-325.

Molecular Mechanisms Behind the Chemopreventive Effects of Anthocyanidins.Hou DX, Fujii M, Terahara N, Yoshimoto M.Anthocyanins are polyphenolic ring-based flavonoids, and are widespread in fruits and vegetables of red-blue color. Epidemiological investigations and animal experiments have indicated that anthocyanins may contribute to cancer chemoprevention. The studies on the mechanism have been done recently at molecular level. This review summarizes current molecular bases for anthocyanidins on several key steps involved in cancer chemoprevention: (i) inhibition of anthocyanidins in cell transformation through targeting mitogen-activated protein kinase (MAPK) pathway and activator protein 1 (AP-1) factor; (ii) suppression of anthocyanidins in inflammation and carcinogenesis through targeting nuclear factor kappa B (NF- $\kappa$ B) pathway and cyclooxygenase 2 (COX-2) gene; (iii) apoptotic induction of cancer cells by anthocyanidins through reactive oxygen species (ROS) / c-Jun NH(2)-terminal kinase (JNK)-mediated caspase activation. These data provide a first molecular view of anthocyanidins contributing to cancer chemoprevention.PMID: 15577196

Regards.

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