5 oil fats, blood pressure and heart blood vessels

[Guest guest]

Hi All,

The pdf-available below paper compares oil fats

for their effects on hypertension, heart cells and

heart blood vessels. Some, especially fish oil, are

superior for the health of the heart.

My area of expertise and interest is mainly in the

blood pressure and fat composition issues, so the

other, I find technical, aspects of the paper are not

presented beyond what is in the abstract.

Included below the abstract, are excerpts from

the text and a table and a figure.

First, is the description of the effects of the oils

on blood lipids, which unfortunately did not

provide details.

Then, there are concluding text excerpts, which

was excerpted because the remainder was a copy

of that in the abstract conclusions.

Then there is the first table excerpts, which compare

all five oil fatty acids in a manner of interest to me.

Finally, are the relevant to me results of the five oils

on blood pressure.

Oil of fish favors favorable blood pressure very

effectively, it seems. We do as CRers have low

enough blood pressures overall, but why this is

so for individuals may favor fats that are

differentially consumed.

Unfortunately, the study is in hypertensive animals,

but this allows, I believe, an amplification for the effects

on blood pressure.

J Hypertens. 2004 May;22(5):921-9.

Effects of long-term intake of edible oils on hypertension and

myocardial and

aortic remodelling in spontaneously hypertensive rats.

Aguila MB, Sa Silva SP, Pinheiro AR, Mandarim-de-Lacerda CA.

... Six groups of 3-month-old male spontaneously hypertensive rats

(n = 5)

received different edible oils (fish, canola, palm, olive and soybean

oils, 1.5

g/kg per day + 1 IU/ml vitamin E) or a placebo (water) by gavage for

13 weeks.

Stereology was used to analyse left ventricular cardiomyocytes,

intramyocardial

vessels, connective tissue, aortic lamellae and tunica media smooth

muscle

cells. RESULTS: Fish oil decreased blood pressure, and increases in

blood

pressure were prevented by both canola and palm oils. The

cardiomyocyte and

intramyocardial vessel indices were greater in the fish-, canola- and

palm-oil

groups and smaller in the soybean-oil, olive-oil and control groups;

the

opposite effects were found in interstitial connective tissue. The

number of

lamellae was smaller in the fish-oil group but greater in the soybean-

oil,

canola-oil, and olive-oil groups. Canola oil reduced aortic wall

thickness, but

palm oil did not. The number of smooth muscle cells was smaller in

the groups

given fish, canola and olive oils. CONCLUSION: The most beneficial

cardiac and

aortic structural effects occurred in the fish-oil group. Both canola

oil and

palm oil were also effective in reducing blood pressure, favouring

myocardial

remodelling, although they produced contrasting effects with regard

to aorta

wall structure. Soybean oil and olive oil had mild effects on

myocardial and

aortic structure.

PMID: 15097231 [PubMed - indexed for MEDLINE]

... Blood lipids

Blood cholesterol and triglyceride concentrations were

not different among the groups: the cholesterol concen-tration

ranged from 1.28 to 1.72 mmol/l and triglyceride

concentrations from 0.49 to 0.94 mmol/l.

... However, both canola oil and palm oil were also effec-tive

in blood pressure reduction, favouring myocardial

structure (they can thus be a good choice for vegetar-ians

and those who do not eat seafood), but they had

different effects with respect to aortic wall structure:

canola oil reduced wall hypertrophy, but palm oil

apparently did not. ...

Table 1

Fatty acid Soybean Olive Canola Palm Fish

P:S:M 4:1:3 1:1.5:8 4:1:2 1:5:1.5 1.3:1:1.5

N-6:N-3 6:1 9:1 3:1 20:1 0.5:1

P+M/S 5.4 5.8 11.2 0.9 1.4

Polyunsaturated (P), Saturated (S), Mono-unsaturated (M), Omega (N)

Fig. 1

Systolic blood pressue of fatty acid FA in

FA Control Soybean Olive Canola Palm Fish

mm Hg 172 166 161 140.5 145.5 116.5

Cheers, Al Pater.