CLL mimicking recurrent carcinoma of the breast: Case report and review of the literature.

[Guest guest]

BlankChronic lymphocytic leukemia mimicking recurrent carcinoma of the breast:

Case report and review of the literature.

X Catteau, MF Dehou, JL Dargent, M Hackx, and JC Noel

Pathol Res Pract, June 18, 2011;

Pathology Department, Erasme Hospital, Free University of Brussels, Belgium.

Secondary localization of chronic lymphocytic leukemia (CLL) in breast is rare,

while concurrent invasive ductal carcinoma and CLL manifesting as a collision

tumor in breast is extremely rare. The observation of a CLL infiltration closely

associated with a distinct breast neoplasm with the absence of any other

localization for the leukemia is an indisputable argument for a relationship

between the two diseases. The presence of both tumors is not simply due to

chance. This association (CLL and carcinoma) has also been described in other

organs. Hereafter, we report a second case of an 80 year-old woman in whom a

leukemic infiltrate was confined to the region immediately surrounding poorly

differentiated primary breast carcinoma, and we will discuss the association

between CLL and carcinoma.

PMID: 21689894