454 Sequencing, Phylogenetics Reveal Cancer Cell Evolution

[Guest guest]

Again, the link to this paper comes from the CLL Alternative group.

To give you an idea of what you'll be reading, here's a brief quote.

" In order to discern real variants from sequencing artifacts, the

researchers developed a bioinformatic algorithm to weed out common

sequencing errors. Once these artifactual insertions, deletions, and

substitutions were accounted for, the researchers were able to

identify genuine somatic mutations that were present in as few as one

in every 5,000 cells. "

In order to read the paper, you will need to register, but the service

is free.

http://www.genomeweb.com/issues/news/148782-1.html

Warm wishes,

Jan