Autologous stem cell transplantation as a first-line treatment strategy for CLL

[Guest guest]

Even for non-CLL person, or if auto sct is not in your future, this is a

good paper to read to get a feel for how good studies are conducted and

reported . and the complexity of interpreting study results as well.

~ Karl

.. Autologous stem cell transplantation as a first-line treatment

strategy for CLL: a multicenter, randomized, controlled trial

http://bit.ly/je7iRh

snip: " This is the first published randomized clinical trial of ASCT as

part of the first-line treatment for patients with stage B or C CLL.

We found that ASCT doubled the EFS (effect free survival) probability in

patients who entered CR after up-front chemotherapy.

This is consistent with the results of previous phase 2 trials of ASCT for

first-line treatment consolidation, in which the median EFS ranged from

5-6.3 years.19-21 In contrast, ASCT was not more beneficial than FC in our

non-CR patients rescued with DHAP. "

All the best,

~ Karl

Patients Against Lymphoma

Patients Helping Patients

Non-profit | Independent | Evidence-based

www.lymphomation.org | Current News: http://bit.ly/f2A0T

How to Help: www.lymphomation.org/how-to-help.htm