What Is IVIG and What Does IVIG Treat?

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What Is IVIG and What Does IVIG Treat?

21. May 2008

Intravenous Immunoglobulin (IVIg) is a solution of highly purified

immunoglobulin G, derived from large pools of human plasma that contain

antibodies against a broad spectrum of bacterial and viral agents. This solution

is delivered intravenously and is used primarily to treat three categories of

illnesses: immunodeficiencies, autoimmune neuromuscular disorders, and certain

rheumatologic conditions.

NOTE: IVIg is also known as IGG, IVIG, IGIV, immune globulin, immunoglobulin,

and immune globulin intravenous (human) (systemic).

Patients with primary immune defeciencies usually receive treatment therapy for

life and patients being treated for autoimmune neuromuscular disorders and

rheumatologic conditions tend to receive therapy for a more limited period which

may be months or years.

What Does IVIG Treat?

IVIG Therapy has been used extensively in the treatment and prevention of a

variety of infectious and inflammatory diseases. Patients with compromised

Immune systems who have these conditions often benefit from the passive immunity

provided by IVIG therapy.

IVIG is used in patients with primary immunodeficiencies and certain conditions

associated with B-cell Chronic Lymphocytic Leukemia, Pediatric HIV, and Bone

Marrow Transplant. IVIG is also utilized to raise platelet counts in patients

with Idiopathic Thrombocytopenic Purpura and to treat the symptoms related to

other clinical conditions such as Kawasaki Syndrome.