CR +/- fiber

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Hi All,

" Dietary fibre supplementation, rather than energy intake and dietary

restriction, appears to be the main process retarding oxidative stress in

cardiac

tissue " ?

It surprises.

Can J Physiol Pharmacol. 2003 Nov;81(11):1042-8.

Dietary restriction and fibre supplementation: oxidative stress and metabolic

shifting for cardiac health.

Diniz YS, Cicogna AC, Padovani CR, Silva MD, Faine LA, Galhardi CM, Rodrigues

HG,

Novelli EL.

... Male Wistar rats (180-200 g; n=10) were divided into four groups: control

ad

libitum diet ©, 50% restricted diet (DR), fed with fibre-enriched diet (F),

and

50% restricted fibre-enriched diet (DR-F). After 35 days of the treatments, F,

DR,

and DR-F rats showed low cholesterol, LDL-cholesterol, and triacylglycerol, and

high

HDL-cholesterol in serum. The DR, DR-F, and F groups had decreased myocardial

lipoperoxide and lipid hydroperoxide. The DR-F and F treatments increased

superoxide

dismutase and glutatione peroxidase (GSH-Px). The DR treatment increased GSH-Px

and

catalase activities. Dietary fibre beneficial effects were related to metabolic

alterations. The F and DR-F groups showed high cardiac glycogen and low lactate

dehydrogenase/citrate synthase ratios, indicating diminished anaerobic and

elevated

aerobic myocardial metabolism in these animals. There was no synergistic effect

between dietary restriction and dietary fibre addition, since no differences

were

observed in markers of oxidative stress in the F and DR-F groups. Dietary fibre

supplementation, rather than energy intake and dietary restriction, appears to

be

the main process retarding oxidative stress in cardiac tissue.

PMID: 14719039

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\

ct & list_uids=14719039

Al Pater, PhD; email: old542000@...

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