Re: First Treatment coming up (ABT 263?)

September 19, 2011

Sorry, I meant to post this in the group....

But, if anyone has opinions, pleae feel free to reply!

Thanks

>

> Hello folks,

>

> I would appreciate input on the " ABT-263 plus High-Dose Retuximab or High-Dose

Retux only " clinical trial as a first line of treatment.

>

> I've been on W & W since 2004 with Dr. Kipps and feel very fortunate to have

gone that long (Unmutated, 65% Zap 70+, but with 13q14). I'm definitely feeling

a much lower energy level these days.

>

> In view of the promising treatments coming along, I'd like to avoid using

chemo agents this first time around to preserve as much health as possible. I

would greatly appreciate people's thoughts on this and to hear if anyone is has

participated in this trial.

>

> Thanks very much.

> Sharon

> The numbers:

> WBC=84, 90% lymphocytes, 10% neuts, 14.2% hemoglobin, 161 platelets, 2.5 B2M,

Low IG's, 4.92 RBC.

> Growing nodes; spleen @ 6 cm, liver @ 14 cm.

>

September 20, 2011

The trial has three arms, and only one is right for me, so I

decided not to participate. You might do well on the Rituxan

only - it's not right for me. The other two arms are:

1) Rituxan plus ABT-263 until the end of the trial, or

2) Rituxan plus ABT-263 for as long as you don't progress.

From what I have read, when you discontinue drugs like

ABT-263 you get a big bounce in your disease, so I'm not

interested in that. Basically, it's a 1 of 3 chance to get

into the best trial arm.

Ron

Sharon wrote:

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