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creatinine clearance and pretreat hem parameters predict fludarabine toxicity

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Analysis of age, estimated creatinine clearance and pretreatment hematologic

parameters as predictors of fludarabine toxicity in patients treated for chronic

lymphocytic leukemia: a CALGB (9011) coordinated intergroup study

http://bit.ly/nGgKCi

" A time-to-toxicity endpoint was evaluated over the entire course of fludarabine

treatment. Creatinine clearance (CrClest) was estimated using serum creatinine,

age and body mass index. "

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