Researchers find four mutations that 'drive' CLL

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Cancer research project identifies mutated genes

LISA PRIEST

From Monday's Globe and Mail

Published in Nature on Sunday, Spanish researchers have identified the recurrent

mutations of four genes that cause chronic lymphocytic leukemia, a cancer of the

blood and bone marrow.

snip

In this particular research, Spanish Chronic Lymphocytic Leukemia Genome

Consortium scientists found 1,000 mutations in more than 300 patients with

chronic lymphocytic leukemia studied, of which four were particularly relevant.

" The diagnosis of disease is moving away from the organ towards the mutation and

it's the mutation that becomes the basis of selection therapy, " Dr. Hudson said

in a telephone interview. " And that becomes personalized medicine. "

snip

http://www.theglobeandmail.com/life/health/new-health/health-news/cancer-researc\

h-project-identifies-mutated-genes/article2048195/