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Re: Reactive Oxygen Species and ORAC

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Recall the some of the genes we cart around encode antioxidant enzymes

(catalase and a variety of peroxidases). Somewhere I have some

journal articles of research which demonstrates that to a degree, the body

compensates dietary intake of antioxidant compounds by reductions in gene

expression of antioxidant enzymes.

citpeks wrote:

One of the reasons why there is much interest

about the Oxygen Radical

Absorption Capacity (ORAC) of foods is that oxygen radicals are

very

reactive and are thought to contribute to premature aging and cancer,

but I think that some aspects of our lifestyle may undo what we

try to

accomplish by eating high ORAC foods.

In particular, I was thinking that the hydrogen peroxide in tooth

whiteners (mouthwashes, dental strips, and toothpastes) may contribute

more Reactive Oxygen Species (ROS) than can be neutralized by dietary

ORAC in food. There have been investigations of mouth cancer

and

tooth whiteners, but although two cases have been reported, an

iron-clad case has not been made:

http://my.webmd.com/content/article/92/101691.htm

However, ROS are necessary for some of our biological functions,

such

as the ability of neutrophils (white cells) to kill engulfed pathogens

by using the enzyme myeloperoxidase:

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/ROS.html

I recently got a free sample of Listerine Whitening Pre-Brush Rinse

which literally makes you foam at the mouth. I think that

I will use

it to clean my toilet bowl instead, and keep my ivory-colored smile.

Tony

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Lifeline says otherwise:

http://www.lifelinetherapeutics.com/breaking-news.htm

On 6/2/05, Albaugh <albaughg@...> wrote:

Recall the some of the genes we cart around encode antioxidant enzymes (catalase and a variety of peroxidases). Somewhere I have some journal articles of research which demonstrates that to a degree, the body compensates dietary intake of antioxidant compounds by reductions in gene expression of antioxidant enzymes. citpeks wrote: One of the reasons why there is much interest about the Oxygen Radical Absorption Capacity (ORAC) of foods is that oxygen radicals are very reactive and are thought to contribute to premature aging and cancer,

but I think that some aspects of our lifestyle may undo what we try to accomplish by eating high ORAC foods. In particular, I was thinking that the hydrogen peroxide in tooth whiteners (mouthwashes, dental strips, and toothpastes) may contribute more Reactive Oxygen Species (ROS) than can be neutralized by dietary

ORAC in food. There have been investigations of mouth cancer and tooth whiteners, but although two cases have been reported, an iron-clad case has not been made: http://my.webmd.com/content/article/92/101691.htm However, ROS are necessary for some of our biological functions, such as the ability of neutrophils (white cells) to kill engulfed pathogens by using the enzyme myeloperoxidase: http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/ROS.html

I recently got a free sample of Listerine Whitening Pre-Brush Rinse which literally makes you foam at the mouth. I think that I will use it to clean my toilet bowl instead, and keep my ivory-colored smile.

Tony

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Take a look at this: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=15734732 & query_hl=19

Dietary antioxidants tend to be biphasic in nature. At low concentrations

many appear to operate as antioxidants. However at high concentrations

many antioxidants behave as prooxidants. The abandoned beta-carotene/smoker

human studies both in Finland and here in the US are a testament to that.

Dowling wrote:

Lifeline says otherwise: http://www.lifelinetherapeutics.com/breaking-news.htm

On 6/2/05, Albaugh <albaughg@...>

wrote:

Recall

the some of the genes we cart around encode antioxidant enzymes (catalase

and a variety of peroxidases). Somewhere I have some journal

articles of research which demonstrates that to a degree, the body compensates

dietary intake of antioxidant compounds by reductions in gene expression

of antioxidant enzymes.

citpeks wrote:

One of the reasons why there is much

interest about the Oxygen Radical

Absorption Capacity (ORAC) of foods is that oxygen radicals are

very

reactive and are thought to contribute to premature aging and cancer,

but I think that some aspects of our lifestyle may undo what we

try to

accomplish by eating high ORAC foods.

In particular, I was thinking that the hydrogen peroxide in tooth

whiteners (mouthwashes, dental strips, and toothpastes) may contribute

more Reactive Oxygen Species (ROS) than can be neutralized by dietary

ORAC in food. There have been investigations of mouth cancer

and

tooth whiteners, but although two cases have been reported, an

iron-clad case has not been made:

http://my.webmd.com/content/article/92/101691.htm

However, ROS are necessary for some of our biological functions,

such

as the ability of neutrophils (white cells) to kill engulfed pathogens

by using the enzyme myeloperoxidase:

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/ROS.html

I recently got a free sample of Listerine Whitening Pre-Brush Rinse

which literally makes you foam at the mouth. I think that

I will use

it to clean my toilet bowl instead, and keep my ivory-colored smile.

Tony

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Yes. Complex issue. Certainly, high levels of antioxidants can lead to problems in various ways.

On 6/2/05, Albaugh <albaughg@...> wrote:

Take a look at this:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=15734732 & query_hl=19 Dietary antioxidants tend to be biphasic in nature. At low concentrations many appear to operate as antioxidants. However at high concentrations many antioxidants behave as prooxidants. The abandoned beta-carotene/smoker human studies both in Finland and here in the US are a testament to that.

Dowling wrote: Lifeline says otherwise: http://www.lifelinetherapeutics.com/breaking-news.htm

On 6/2/05, Albaugh <albaughg@...> wrote:

Recall the some of the genes we cart around encode antioxidant enzymes (catalase and a variety of peroxidases). Somewhere I have some journal articles of research which demonstrates that to a degree, the body compensates dietary intake of antioxidant compounds by reductions in gene expression of antioxidant enzymes. citpeks wrote: One of the reasons why there is much interest about the Oxygen Radical Absorption Capacity (ORAC) of foods is that oxygen radicals are very reactive and are thought to contribute to premature aging and cancer,

but I think that some aspects of our lifestyle may undo what we try to accomplish by eating high ORAC foods. In particular, I was thinking that the hydrogen peroxide in tooth whiteners (mouthwashes, dental strips, and toothpastes) may contribute more Reactive Oxygen Species (ROS) than can be neutralized by dietary

ORAC in food. There have been investigations of mouth cancer and tooth whiteners, but although two cases have been reported, an iron-clad case has not been made: http://my.webmd.com/content/article/92/101691.htm However, ROS are necessary for some of our biological functions, such as the ability of neutrophils (white cells) to kill engulfed pathogens by using the enzyme myeloperoxidase: http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/ROS.html

I recently got a free sample of Listerine Whitening Pre-Brush Rinse which literally makes you foam at the mouth. I think that I will use it to clean my toilet bowl instead, and keep my ivory-colored smile.

Tony

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