Speaking of coffee......

[Guest guest]

I thought it was interesting that acrylamide " so far " has gotten

the " all-clear " from the scientific community " from the clinical end

of the spectrum " , although I am sure the basic scientists are still

fretful about it.

In any case, I thought it was interesing that coffee is a dietary

foodstuff thought to be harboring much of the maligned chemical.

Int J Cancer. 2005 Jul 7; [Epub ahead of print]

Channing Laboratory, Brigham and Women's Hospital, Harvard Medical

School, Boston, MA, USA.

" We have undertaken the first prospective study of acrylamide in food

and risk of colon and rectal cancers using prospective data from the

Swedish Mammography Cohort. The cohort comprised 61,467 women at

baseline between 1987 and 1990. Through 2003, the cohort contributed

823,072 person-years, and 504 cases of colon and 237 of rectal cancer

occurred. Mean intake of acrylamide through diet was 24.6 mug/day

(Q25-70 = 18.7-29.9). Coffee (44%), fried potato products (16%),

crisp bread (15%) and other breads (12%) were the greatest

contributors. After adjusting for potential confounders, there was no

association between estimated acrylamide intake and colorectal

cancer. Comparing extreme quintiles, the adjusted relative risks (95%

CI; p for trend) were for colorectal cancer 0.9 (0.7-1.3; p = 0.80),

colon cancer 0.9 (0.6-1.4; p = 0.83) and rectal cancer 1.0 (0.6-1.8;

p = 0.77). Furthermore, intake of specific food items with elevated

acrylamide (e.g., coffee, crisp bread and fried potato products) was

not associated with cancer risk. In this large prospective study, we

found no evidence that dietary intake of acrylamide is associated

with cancers of the colon or rectum. Epidemiologic studies play an

important role in assessing the possible health effects of acrylamide

intake through food. " - PMID: 16003738

http://tinyurl.com/adpvt

T.

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