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Re: JAMA: Coffeeprevents Type 2 Diabetes

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Hi :

I wonder whether the incidence of type II diabetes is less in the US

than in the UK where tea is the predominant hot beverage? Obesity is

high in both countries, although probably somewhat higher in the US.

Rodney.

--- In , " pct35768 " <pct35768@y...>

wrote:

> This research is appearing in the Journal of the American Medical

> Association, and is the result of a " literature review " .

>

> There are endocrinological/molecular reasons why this is probably

> true. But, I guess one could begin to argue that there are " other

> reasons " why coffee may be bad for you, but they usually have quite

a

> hard time finding them on a consistent basis.

>

> =--==-==--==--=-=

>

> JAMA. 2005 Jul 6;294(1):97-104

>

> CONCLUSIONS: This systematic review supports the hypothesis that

> habitual coffee consumption is associated with a substantially

lower

> risk of type 2 diabetes. Longer-term intervention studies of coffee

> consumption and glucose metabolism are warranted to examine the

> mechanisms underlying the relationship between coffee consumption

and

> type 2 diabetes. - PMID: 15998896

>

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

> cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=15998896

>

> =--==--==-=-=-=-=-==-

>

> T.

> pct35768@y...

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Hi :

I just did a Google search:

At drlenkravitz.com it says there are 18.3 million diabetics in the

US. Which is about 6.2% of the population.

At a NHS (UK) website it say there are 1.3 million diabetics in the

UK. Which is about 2.2% of the population.

Google's UK reference is:

" Encyclopaedia Topic : Diabetes, Section : Introduction

Diabetes affects 1.3 million people in the UK and there may be as

many as a ...

Nine out of ten people with diabetes have type II diabetes and over

80% of ...

www.nhsdirect.nhs.uk/ en.asp?TopicID=157 & AreaID=4207 & LinkID=3282 -

34k - Cached - Similar pages "

and:

http://www.nhsdirect.nhs.uk/en.asp?TopicID=157

Hmmmm. So if coffee is good, is tea better? Or perhaps fewer are

diagnosed in the UK?

Rodney.

> > This research is appearing in the Journal of the American Medical

> > Association, and is the result of a " literature review " .

> >

> > There are endocrinological/molecular reasons why this is probably

> > true. But, I guess one could begin to argue that there

are " other

> > reasons " why coffee may be bad for you, but they usually have

quite

> a

> > hard time finding them on a consistent basis.

> >

> > =--==-==--==--=-=

> >

> > JAMA. 2005 Jul 6;294(1):97-104

> >

> > CONCLUSIONS: This systematic review supports the hypothesis that

> > habitual coffee consumption is associated with a substantially

> lower

> > risk of type 2 diabetes. Longer-term intervention studies of

coffee

> > consumption and glucose metabolism are warranted to examine the

> > mechanisms underlying the relationship between coffee consumption

> and

> > type 2 diabetes. - PMID: 15998896

> >

> > http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

> > cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=15998896

> >

> > =--==--==-=-=-=-=-==-

> >

> > T.

> > pct35768@y...

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--- In , " Rodney " <perspect1111@y...>

wrote:

> Hi :

>

> I wonder whether the incidence of type II diabetes is less in the

US

> than in the UK where tea is the predominant hot beverage? Obesity

is

> high in both countries, although probably somewhat higher in the US.

>

> Rodney.

Sheesh, Rodney, get a clue! The literature very CLEARLY states

that..................it depends on who you ask. :)

In reality, I honestly think the personal predilections of the

investigator in regards to stimulant use (and abuse) guide research

findings just as much as the data. So, in other words, Eastern

cultures may promote research showing that green tea has " special

benefits " , while Western coffee drinkers may promote literatue

emphasizing coffee, and so on.

From a biochemical standpoint, I see a lot of studies indicating the

specific melanoid products from coffee roasting could promote health,

and that catechin compounds from teas could promote health. Some

people want to emphasize caffeine itself, as well.

So, there is a polyphenolic/bioactive profile associated with

any " natural substance " , and that will endow said substance with a

its

own " qualities " that may be irreducible, although perhaps that is a

stretch.

However, for better or worse, there is a " cluster " around " dietary

stimulants " , of coffee, black tea, and green tea, and they usually

tend

to find more " good " things than " bad " things about them.

T.

pct35768@...

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Hi :

Not sure what you are trying to tell me here.

I have already posted that it appears there is about 60% LESS

diabetes in the UK - a predominantly tea drinking country - than

there is in the US - a mostly coffee-drinking country.

So, the question remains, if coffee is good at least one piece of

evidence appears to suggest that it doesn't make a huge amount of

difference in comparison with tea.

But of course there are other factors involved in diabetes incidence,

besides what kind of hot beverage a country drinks. Nevertheless,

the difference does seem to be HUGE, and certainly suggests the

influence of coffeee is relatively marginal.

Or do you have an alternative interpretation?

Rodney.

> > Hi :

> >

> > I wonder whether the incidence of type II diabetes is less in the

> US

> > than in the UK where tea is the predominant hot beverage? Obesity

> is

> > high in both countries, although probably somewhat higher in the

US.

> >

> > Rodney.

>

> Sheesh, Rodney, get a clue! The literature very CLEARLY states

> that..................it depends on who you ask. :)

>

> In reality, I honestly think the personal predilections of the

> investigator in regards to stimulant use (and abuse) guide research

> findings just as much as the data. So, in other words, Eastern

> cultures may promote research showing that green tea has " special

> benefits " , while Western coffee drinkers may promote literatue

> emphasizing coffee, and so on.

>

> From a biochemical standpoint, I see a lot of studies indicating

the

> specific melanoid products from coffee roasting could promote

health,

> and that catechin compounds from teas could promote health. Some

> people want to emphasize caffeine itself, as well.

>

> So, there is a polyphenolic/bioactive profile associated with

> any " natural substance " , and that will endow said substance with a

> its

> own " qualities " that may be irreducible, although perhaps that is a

> stretch.

>

> However, for better or worse, there is a " cluster " around " dietary

> stimulants " , of coffee, black tea, and green tea, and they usually

> tend

> to find more " good " things than " bad " things about them.

>

> T.

> pct35768@y...

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> > > Hi :

> > >

> > > I wonder whether the incidence of type II diabetes is less in

the

> > US

> > > than in the UK where tea is the predominant hot beverage?

Obesity

> > is

> > > high in both countries, although probably somewhat higher in

the

> US.

> > >

> > > Rodney.

> >

> > Sheesh, Rodney, get a clue! The literature very CLEARLY states

> > that..................it depends on who you ask. :)

> >

> > In reality, I honestly think the personal predilections of the

> > investigator in regards to stimulant use (and abuse) guide

research

> > findings just as much as the data. So, in other words, Eastern

> > cultures may promote research showing that green tea has " special

> > benefits " , while Western coffee drinkers may promote literatue

> > emphasizing coffee, and so on.

> >

> > From a biochemical standpoint, I see a lot of studies indicating

> the

> > specific melanoid products from coffee roasting could promote

> health,

> > and that catechin compounds from teas could promote health. Some

> > people want to emphasize caffeine itself, as well.

> >

> > So, there is a polyphenolic/bioactive profile associated with

> > any " natural substance " , and that will endow said substance with a

> > its

> > own " qualities " that may be irreducible, although perhaps that is

a

> > stretch.

> >

> > However, for better or worse, there is a " cluster "

around " dietary

> > stimulants " , of coffee, black tea, and green tea, and they usually

> > tend

> > to find more " good " things than " bad " things about them.

> >

> > T.

> > pct35768@y...

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Hi :

Not angry. Just thought you didn't agree.

I can see that studies which are trying to determine whether a health

benefit can be derived from a local food are quite likely to be

biased.

But it seems rather unlikely to me that a statistic for the number of

diagnosed diabetics in a country is likely to be biased by the

statistician who happens to be adding up the numbers.

There are other possible reasons for the apparent differences in

diabetes prevalence. Less diagnosis. Other foods. Different

environmental conditions. Different rates of obesity. Different

genetic backgrounds. .................

Obesity is a bit lower in the UK I believe. But I would think the

diagnosis rate may be higher since every person in the country has

free access to a doctor for health consultations, whereas we keep

hearing that (what is it 30%?) a significant proportion of the US

population has no health insurance and cannot afford medical services.

So the different prevalence rates are probably significant, imo, fwiw.

As for my own biases, I used to drink mostly coffee. I became biased

by the numerous studies which showed notable benefits for tea. So my

bias is based on the evidence. And if future evidence shows

remarkable benefits for coffee I will be more than happy to switch

back.

Rodney.

> > > > Hi :

> > > >

> > > > I wonder whether the incidence of type II diabetes is less in

> the

> > > US

> > > > than in the UK where tea is the predominant hot beverage?

> Obesity

> > > is

> > > > high in both countries, although probably somewhat higher in

> the

> > US.

> > > >

> > > > Rodney.

> > >

> > > Sheesh, Rodney, get a clue! The literature very CLEARLY states

> > > that..................it depends on who you ask. :)

> > >

> > > In reality, I honestly think the personal predilections of the

> > > investigator in regards to stimulant use (and abuse) guide

> research

> > > findings just as much as the data. So, in other words, Eastern

> > > cultures may promote research showing that green tea

has " special

> > > benefits " , while Western coffee drinkers may promote literatue

> > > emphasizing coffee, and so on.

> > >

> > > From a biochemical standpoint, I see a lot of studies

indicating

> > the

> > > specific melanoid products from coffee roasting could promote

> > health,

> > > and that catechin compounds from teas could promote health.

Some

> > > people want to emphasize caffeine itself, as well.

> > >

> > > So, there is a polyphenolic/bioactive profile associated with

> > > any " natural substance " , and that will endow said substance

with a

> > > its

> > > own " qualities " that may be irreducible, although perhaps that

is

> a

> > > stretch.

> > >

> > > However, for better or worse, there is a " cluster "

> around " dietary

> > > stimulants " , of coffee, black tea, and green tea, and they

usually

> > > tend

> > > to find more " good " things than " bad " things about them.

> > >

> > > T.

> > > pct35768@y...

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Just a quick comment from the UK, a little annecdotal I suppose.

Blood sausage (black pudding) is disliked by many nowadays, perhaps

not as popular as it once was, and scones and clotted cream are

lovely when visiting Devon or Cornwall but most of us wouldn't do

that often. Scones can be bought in the supermarket but frankly,

are probably not as bad as some of the other 'cake' options, not

that I would buy them.

Coffee tends to be more popular among the younger generation whereas

as the older generation are probably more likely to have a cuppa eg

my Mom and Dad drank tea, I drank coffee but have now switched to

green tea. A lot of people my age, 53, and younger will perhaps not

be the avid tea drinkers their parents were!

Maybe more relevant, is the point about access to free healthcare.

If you go to your GP at the drop of a hat and he suggests getting a

bit of weight off, something is bound to rub off on some of us in

time <grin>. We tend to think not enough people take dietary advice

(maybe just as well in some cases) but there will always be a

proportion that cut back on fat, salt or whatever. It surely has to

affect the figures?

Gay

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Hi JW:

The same arguments can (and should?) be made about all foods. For

example, most agree that fish is net beneficial, but the fatty fish

(and the fish oils that come in capsules) all contain some myristic

acid, which most observers believe to be harmful.

In a hundred years I do not doubt we will have fish in the stores

that have been bred/gene-spliced so that the myristic is eliminated.

Rodney.

--- In , " jwwright " <jwwright@e...>

wrote:

> I've wondered why we brew coffee and especially tea.

> Some PCa patients EAT the green tea. After all, if the brew is good

the whole has to be better (?). They add it to stews, eg. When you

have PCa I guess you try anything for alternative medicine.

> I would think though that anyone who thinks tea is good should use

the capsules, eg., but even those have been processed, so like the

herbs I sometimes grow, the fresh leaves are much more potent. Try

fresh basil in pesto, eg.

> TOL, I could try green tea in a pesto.

> As a spice, green tea is potent like your typical " Italian " spice,

so I have to wonder if tea shouldn't be considered a spice.

>

> If anyone wants to look at tea's contents:

> http://www.ars-grin.gov/duke/index.html

> This provides the chems and the activities.

> http://www.ars-grin.gov/cgi-bin/duke/farmacy2.pl

> If half this stuff is true, we would never be sick again. I would

not have hypertension, eg.

> There are many unknowns. Do we really want to use chemicals we know

little about?

>

> CATECHIN Leaf 85 - 12,700 ppm

> ACE-Inhibitor 0.24 mg/ml rbt (weak activity) IC50=0.155 mM/l;

Antiaggregant IC68=200 ug/ml; Anticoagulant; Anticomplementary 1/2

aspirin; AntiHIV EC50=4 ug/ml; Antiinflammatory IC50=40-943 uM (cf

indomethacin IC50=1 uM); Antimutagenic ID50=50-100 nM; Antioxidant;

Antiperoxidant; Antiprostaglandin IC50=40-943 uM (cf indomethacin

IC50=1 uM); Antiradicular; Antiulcer; Beta-Adrenergic Receptor

Blocker 10 uM (weak activity); cAMP-Phosphodiesterase-Inhibitor;

Cancer-Preventive; Cardiotonic; COX-1-Inhibitor IC50=183-279 uM (cf

indomethacin IC50=1 uM); COX-2-Inhibitor IC50=546-5,910 uM (cf

indomethacin IC50=1 uM); Cyclooxygenase-Inhibitor; Cytotoxic

TC50=>100 ug/ml; Dermatitigenic; Hemostat; Hepatoprotective;

Immunostimulant; Phagocytotic; Vasoconstrictor; Xanthine-Oxidase-

Inhibitor

> 1,3,5-TRIHYDROXY-BENZENE Leaf:

> Prostaglandin-Synthesis-Inhibitor IC50=45 uM

> 4-TERPINEOL Leaf:

> Antiasthmatic; Antioxidant; Diuretic; FLavor FEMA 20-100;

Insectifuge; Perfumery; Pesticide {keeps you awake}

> ADENINE Leaf:

> Antianemic 1.5 g/day; Antigranulocytopenic; Antiviral; CNS-

Stimulant; Diuretic; Hyperuricemic; Insectifuge; Lithogenic;

Myocardiotonic; Pesticide; Vasodilator

> ALANINE Plant:

> Antioxidant; Cancer-Preventive; Oxidant

> ALLANTOIN Plant:

> Antidandruff; Antiinflammatory; Antioxidant; Antipeptic 30-130

mg/man/day; Antipsoriac 2%; Antiradicular; Antiulcer;

Immunostimulant; Keratolytic; Sunscreen 0.1%; Suppurative; Vulnerary

> ALPHA-AMYRIN Seed Oil:

> Antiedemic IC43=40 mg/kg ipr rat; Antiinflammatory IC71=1,000 ppm

orl; Antinociceptive; Antitumor; Cytotoxic 50-400; Insectifuge

> ALUMINUM Leaf 690 ppm;

> Antisilicotic; Antivaginitic; Candidicide; Encephalopathic;

Pesticide

> APIGENIN Leaf:

> 11B-HSD-Inhibitor; Antiaflatoxin IC50=2.57 ppm IC50=9.52 uM;

Antiaggregant; Antiallergic; Antiangiogenic 4 uM; Antiarrhythmic;

Antibacterial; Anticomplementary; Antidermatitic; Antiestrogenic;

Antiherpetic 20-54 ug/ml; Antihistaminic IC50=10-35 uM; AntiHIV

IC50=143 ug/ml IC72=200 ug/ml; Antiinflammatory = indomethacin

IC~65=1,000 uM; Antileukemic 20-50 uM; Antimelanomic 1-50 uM;

Antimetastatic; Antimutagenic ID50=10-40 nM; Antioxidant 1.5 x Vit. E

IC28.5=62.5 ug/ml; Antiproliferant 1-50 uM; Antispasmodic EC50=1-5

uM; Antithyroid; Antitumor 1-50 uM; Antitumor (Breast); Antitumor

(Lung); Antitumor (Skin); Antiviral 20-54 ug/ml; Anxiolytic 10 mg/kg;

Apoptotic 12-60 uM; Aromatase-Inhibitor IC65=1 uM/l; Beta-

Glucuronidase-Inhibitor IC50=~40 uM; Calcium-Antagonist?; Cancer-

Preventive; Choleretic; CNS-Depressant; COX-1-Inhibitor IC65=1,000

uM; COX-2-Inhibitor <40 uM IC>65=1,000 uM; Cyclooxygenase-Inhibitor;

Cytochrome-P450-1A1-Inhibitor; Cytotoxic 1-50 uM IC88=10 ug/ml;

Deiodinase-Inhibitor; Differentiator IC40=40 uM MIC=30 uM; Diuretic;

DNA-Protective; Estrogenic 16% genistein EC50=0.1-25 uM/l EC50=1 uM;

Hyaluronidase-Inhibitor IC50+=50-250 uM; Hypotensive; Inotropic; MAO-

Inhibitor; Musculotropic; Mutagenic; Myorelaxant; NADH-Oxidase-

Inhibitor; NO-Synthase-Inhibitor 5-50 uM; Nodulation-Signal;

Ornithine-Decarboxylase-Inhibitor; P21-Inducer 10-70 uM; Pesticide;

PKC-Inhibitor IC50=10 uM; Polyamine-Synthesis-Inhibitor;

Progestational; Protein-Kinase-C-Inhibitor IC50=10-40 uM; PTK-

Inhibitor 10-100 uM; Quinone-Reductase-Inducer 20 uM;

Radioprotective; Sedative 30-100 mg/kg; Sunscreen; Topoisomerase-I-

Inhibitor; Topoisomerase-II-Inhibitor 50 ug/ml IC28=18 uM IC45=180

uM; Uterotrophic EC50=0.1-25 uM/l; Vasodilator

> ASTRAGALIN Leaf:

>

> ACE-Inhibitor ID50=180 ug/ml rat (24 hr.); Aldose-Reductase-

Inhibitor IC30=1 uM IC62=10 uM; Antileukemic; Expectorant;

Hypotensive; Immunostimulant

>

> BENZOIC-ACID Leaf:

>

> Allergenic; Anesthetic; Antibacterial 33-1,250 ppm MBC=800 ug/ml;

Antiotitic; Antipyretic; Antisalmonella MIC=800 ug/ml; Antiseptic 800

ug/ml; Antiyeast MFC=1,600 ug/ml; Choleretic; Expectorant; FLavor

FEMA 250; Fungicide MFC=1,600 ug/ml; Insectifuge; Pesticide;

Phytoalexin; Tyrosinase-Inhibitor ID50=640 uM ID50=710 uM;

Uricosuric; Vulnerary

>

> BENZYL-ACETATE Leaf:

>

> Acaricide; Cardiotonic; Emetic; FLavor FEMA 35-800; Hypotensive;

Irritant; Laxative; Tumorigenic; Varroacide

> CAFFEINE Leaf 3,810 - 93,000 ppm Shoot 38,100 - 47,900 ppm

>

> (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus;

Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10

mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic;

Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250

mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic

140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat;

Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic;

Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-

Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-

Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30

orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man;

Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive;

Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic;

Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt

15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic

1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat;

Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99

mM; Vasodilator

> CARVACROL Leaf:

> Allergenic; Anesthetic; Anthelmintic; Antialzheimeran?;

Antiatherosclerotic IC50=5.53 uM; Antibacterial MIC 170-290 MIC=39-

625; Anticholinesterase?; Antidiuretic; Antiinflammatory IC50=4 uM;

Antimelanomic IC50=120 uM/l; Antioxidant; Antioxidant (LDL) IC50=5.53

uM; Antiplaque MIC=39-625 ug/ml; Antiprostaglandin; Antiradicular 600

x thymol; Antiseptic 1.5 x phenol; Antispasmodic; Antistaphylococcic;

Antistreptococcic; Antitussive; Candidicide 100-150 ug/ml MIC<0.1

ug/ml; Carminative; Cyclooxygenase-Inhibitor =indomethacin;

Enterorelaxant; Expectorant; FLavor FEMA 10-125; Fungicide;

Insectifuge; Irritant; Nematicide MLC=1 mg/ml; Pesticide;

Prostaglandin-Inhibitor; Tracheorelaxant; Trichomonicide LD100=150

ug/ml; Vermifuge

> CHLOROGENIC-ACID Leaf:

> Aldose-Reductase-Inhibitor IC50=1.8 uM rat (strong activity);

Allelochemic; Allergenic; Analgesic; Antiatherosclerotic;

Antibacterial; Anticancer (Colon); Anticancer (Forestomach);

Anticancer (Liver); Anticancer (Skin); Anticarcinogenic; AntiEBV;

Antifeedant; Antigenotoxic; Antigonadotropic; Antihemolytic 10 uM;

Antihepatotoxic; Antiherpetic; Antihistaminic; AntiHIV;

Antihypercholesterolemic; Antihyperthyroid; Antiinflammatory;

AntiLegionella; Antileukotriene; Antimelanogenic; Antimutagenic;

Antinitrosaminic; Antioxidant IC53=200 ppm IC80=12 uM; Antiperoxidant

IC50=36 uM; Antipolio; Antiradicular 10 uM 9 x quercetin; Antiseptic;

Antisunburn; Antithyroid; Antitumor; Antitumor (Colon); Antitumor

(Forestomach); Antitumor (Liver); Antitumor (Skin); Antitumor-

Promoter IC25=10 uM; Antiulcer; Antiviral; Autotoxic; Cancer-

Preventive; Cholagogue; Choleretic; Clastogenic; CNS-Active; CNS-

Stimulant 1/6 Caffeine; Collagen-Sparing; Diuretic; Fungicide;

Hepatoprotective; Histamine-Inhibitor; Immunostimulant; Insectifuge;

Interferonogenic; Juvabional; Larvistat; Leukotriene-Inhibitor;

Lipoxygenase-Inhibitor IC23=5 mM; Metal-Chelator; NO-Genic; Ornithine-

Decarboxylase-Inhibitor; Oviposition-Stimulant; Pesticide; Sunscreen;

Sweetener; Vulnerary

> CINNAMIC-ACID Leaf:

>

> Aldose-Reductase-Inhibitor 4 ug/ml (weak activity); Allergenic;

Anesthetic; Antibacterial; Antiinflammatory; Antimutagenic;

Antispasmodic; Cancer-Preventive; Choleretic; Dermatitigenic; FLavor

FEMA 4-40; Fungicide; Herbicide; Laxative; Lipoxygenase-Inhibitor;

Pesticide; Vermifuge

> EPICATECHIN Leaf 149 - 21,250 ppm

> Allelochemic IC100=1 mM; Antiaggregant IC94=200 ug/ml;

Antianaphylactic; Antibacterial MIC=>1,000 ug/ml; Anticomplementary

1/2 aspirin; Antidiabetic 30 mg/kg rat; AntiEBV; Antihepatitic;

AntiHIV EC50=2 ug/ml; Antihyperglycemic; Antiinflammatory;

Antileukemic IC50=>10 ug/ml; Antilipoperoxidant; Antimutagenic;

Antioxidant 2.5 x Vit. E IC50=6.3 ug/ml; Antiperoxidant; Antiviral;

Cancer-Preventive; Cardiotonic; Choline-Sparing; Hepatotropic;

Hypocholesterolemic; Hypoglycemic; Insulinogenic; Lipoxygenase-

Inhibitor IC50=140 uM IC97=5 mM; Pancreatogenic; Peroxynitrite-

Scavenger IC50=0.181 ug/ml; Pesticide; Propecic; Xanthine-Oxidase-

Inhibitor IC50=>40

> EPICATECHIN-GALLATE Leaf 5,417 - 31,000 ppm

> Anticariogenic; Antihepatotoxic; Antimutagenic; Antioxidant >10 x

tocopherol; Antiperoxidant; Cancer-Preventive; COMP-Inhibitor;

Glucosyl-Transferase-Inhibitor; Immunostimulant; Lipoxygenase-

Inhibitor IC50=18 uM; Mitogen; Xanthine-Oxidase-Inhibitor IC50=>40

> EPIGALLOCATECHIN Leaf 862 - 31,000 ppm

> Antimutagenic; Antioxidant IC50=1.4 ug/ml; Antiradicular; Beta-

Adrenergic Receptor Blocker 10 uM; Lipoxygenase-Inhibitor IC50=21 uM;

Xanthine-Oxidase-Inhibitor IC50=>40

> EPIGALLOCATECHIN-3-O-GALLATE Leaf 7,140 - 8,718 ppm

> Antiischemic; Antioxidant IC50=0.14 ug/ml; Antiretinopathic

> FARNESOL Leaf:

> Allergenic; Antiadenomic; Anticancer (Pancreas) IC50=39 uM;

Anticarcinomic (Colon); Anticarcinomic (Lung); Antileukemic;

Antimelanomic IC50=50 uM/l; Antispasmodic; Apoptotic; FLavor FEMA 0.1-

3; Juvabional; Nematicide MLC=100 ug/ml; Perfumery; Pesticide;

Pheromonal; Sedative; Trichomonicide LD100=100 ug/ml

> GALLIC-ACID Leaf:

> ACE-Inhibitor IC50=7.7 mM/l; Analgesic; Antiadenovirus;

Antiallergenic; Antianaphylactic; Antiasthmatic; Antibacterial

MIC=1,000 ug/ml; Antibronchitic; Anticancer; Anticarcinomic ED50=3;

Antifibrinolytic; Antiflu; Antihepatotoxic; Antiherpetic EC50=>10

ug/ml; AntiHIV; Antiinflammatory; Antileishmanic EC50=4.4 ug/ml;

Antimutagenic; Antinitrosaminic; Antioxidant 7 x quercetin IC44=33

ppm; Antiperoxidant IC50=69 uM; Antipolio; Antiradicular 7 x

quercetin; Antiseptic; Antistaphylococcic MIC=1,000 ug/ml; Antitumor;

Antitumor-Promoter; Antiviral; Apoptotic; Astringent; Bacteristat;

Bronchodilator; Cancer-Preventive; Carcinogenic; Choleretic;

Cyclooxygenase-Inhibitor; Floral-Inhibitor; Gram(+)icide; Gram(-)

icide; Hemostat; Immunomodulator; Immunostimulant; Immunosuppressant;

Insulin-Sparing; Myorelaxant; Nephrotoxic; Pesticide; Styptic;

Topoisomerase-I-Inhibitor; Xanthine-Oxidase-Inhibitor IC50=24 uM

> GERANIOL Leaf 2 - 2,546 ppm Shoot 800 - 1,200 ppm

> Allergenic; Anthelmintic; Antibacterial MBC=800 ug/ml MIC=400 ug/ml

MIC=64 ug/ml; Anticancer (Pancreas) IC50=265 uM; Anticariogenic

MIC=400 ug/ml; Antimelanomic IC50=150 uM/l; Antisalmonella MIC=400

ug/ml; Antiseptic 400-800 ug/ml 7 x phenol MIC=64 ug/ml;

Antispasmodic; Antitubercular; Antitumor; Antitumor (Pancreas)

IC50=265 uM; Ascaricide; Cancer-Preventive; Candidicide; CNS-

Stimulant; Embryotoxic; Emetic 3 x ipecac; Expectorant; FLavor FEMA 1-

10; Fungicide IC93=2 mM; Herbicide IC100-2,000 uM; Insectifuge 50

ppm; Insectiphile; Mycobactericide MIC=64 ug/ml; Nematicide IC86=100

ug/ml MLC=1,000 ug/ml; Perfumery; Pesticide; Sedative; Trichomonicide

LD100=300 ug/ml

>

> Enough. This isn't the whole list.

>

> Regards.

>

>

> ----- Original Message -----

> From: Gay e

>

> Sent: Friday, July 08, 2005 9:36 AM

> Subject: [ ] Re: JAMA: Coffeeprevents Type 2 Diabetes

>

>

> Just a quick comment from the UK, a little annecdotal I suppose.

>

> Blood sausage (black pudding) is disliked by many nowadays,

perhaps

> not as popular as it once was, and scones and clotted cream are

> lovely when visiting Devon or Cornwall but most of us wouldn't do

> that often. Scones can be bought in the supermarket but frankly,

> are probably not as bad as some of the other 'cake' options, not

> that I would buy them.

>

> Coffee tends to be more popular among the younger generation

whereas

> as the older generation are probably more likely to have a cuppa

eg

> my Mom and Dad drank tea, I drank coffee but have now switched to

> green tea. A lot of people my age, 53, and younger will perhaps

not

> be the avid tea drinkers their parents were!

>

> Maybe more relevant, is the point about access to free

healthcare.

> If you go to your GP at the drop of a hat and he suggests getting

a

> bit of weight off, something is bound to rub off on some of us in

> time <grin>. We tend to think not enough people take dietary

advice

> (maybe just as well in some cases) but there will always be a

> proportion that cut back on fat, salt or whatever. It surely has

to

> affect the figures?

>

> Gay

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Hi Al:

I hope not! I eat some high fat fish almost every day. But it would

be even nicer to be able to eat fish without the myristic. As for

the coffee, should I be drinking both coffee and tea? Maybe the

answer will be found to be " Yes " , but until we see that answer I have

made the choice to use predominantly tea. (I drink coffee when out

of the house because I do not like the way most people prepare tea.)

Fruits usually contain a fair amount of sugar, but I eat fruit

anyway, although I do not personally buy the fruits with the lower

micronutrient/calories ratios - most notably apples. I sometimes eat

peanuts (despite the aflatoxin risk) and more often other nuts

despite the fat content. Indeed I have even been known occasionally

to eat foods that contain dreaded calories ;; ^ ))) <<< that's a

wink!

If you are aware of any other babies I may be discarding with the

bathwater, please let me know. If convinced I will change pretty

much anything about my diet - although I am finding it difficult to

reduce my starch intake. And I am only fairly strict about anything

from Monday to Friday. Without, of course, going out of my way to

eat poor food, I will eat pretty much whatever turns up Saturday and

Sunday.

Rodney.

--- In , Al Pater <old542000@y...>

wrote:

> Hi All,

>

> Rodney, you seem to base the value of a complex food based on small

amounts of

> possibly harmful ingredients. There are many precious babies

thrown out with you

> bathwaters?

>

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