Dwarf mouse every other day feeding

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Hi All,

Here is a paper that is not pdf-available and may suggest that every other day

feeding (EOD) shows some changes that are consistent with what is known

regarding CR

in both normal and Ames dwarf mice.

Masternak MM, Al-Regaiey KA, Bonkowski MS, Panici JA, Bartke A.

Effect of every other day feeding diet on gene expression in normal and in

long-lived Ames dwarf mice.

Exp Gerontol. 2005 May 31; [Epub ahead of print]

PMID: 15935586

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\

ct & list_uids=15935586 & query_hl=1

.... every other day feeding (EOD). Using real-time PCR, we have examined the

expression of genes related to insulin signaling in the liver of normal and

dwarf

mice after 9 months of EOD. The results indicate that EOD produces some changes

in

the insulin and IGF1 signaling pathways, and that these changes are consistent

with

EOD increasing insulin sensitivity.

Al Pater, PhD; email: old542000@...

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