Guest guest Posted June 7, 2005 Report Share Posted June 7, 2005 There have been several so-called " miracle " products since I became a CRONIE in 2000 - everything from certain foods such as blueberries, to certain nutrients (I forget the names) that I ordered in powder form, filled capsules full of (what a pain) and swallowed diligently. I don't get so excited anymore when I hear about these things. I watched the show and decided that it can't be that easy. Until tested and scrutinized by science, I wouldn't swallow the hype on tv (pardon the pun) if I were you. No doubt it's expensive and if you notice it was the developer who was promoting it (and he has everything to gain). I was surprised at the one-sidedness of the report - but then everyone is only too eager to think that they have found the " fountain of youth " . Let's see what happens with it. If history is any guide, it's just another dead-end. on 6/6/2005 7:15 PM, Short at ottawan50@... wrote: > > > I was watching ABC health news on tv, on June 2 and saw a really interesting > interview with Dr Joe McCord. He has developed I think and is to begin testing > and marketing a little yellow pill called Protandim. He claims that it reduces > oxidative stress to the level of a new born, and so potentially could reduce > disease and increase longevity. I looked in the messages and didn't see anyone > react to this unless I missed it. Too bad he is just beginning testing now. It > will not require FDA approval because it has herbal ingredients, 5 of them of > which green tea and turmeric are the best known, which I already use as much > as possible. I think they are putting it on the market rapidly since there is > nothing noxive in the ingredients. I am very limited in my knowledge but > thought i would bring this up if anyone wants to check the health section of > ABC.com, seems promising, and would be interested if anyone has any comments, > if this is new or an old subject, or seems likely to keep us! > all > looking flush like new babies at 85 or 95? > > > > > > > > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 7, 2005 Report Share Posted June 7, 2005 There has been much criticism of this product, for a variety of reasons. One is that the initial press releases regarding development of a life-extension product by Lifeline would be a hitherto unavailable supplement cabable of vastly increasing one's antioxidant production/protection. Eventually, the impetus to release that product was abandoned, apparently due to difficulties in approval by regulatory bodies. So, instead, this (overpriced many say) combination of (readily available) herbal extracts has been released. There is serious doubt regarding its uniqueness and ability to extend life. I've been imbibing many of the ingredients in Protandim for many years, already, as have many others. On 6/6/05, Short <ottawan50@...> wrote: I was watching ABC health news on tv, on June 2 and saw a really interesting interview with Dr Joe McCord. He has developed I think and is to begin testing and marketing a little yellow pill called Protandim. He claims that it reduces oxidative stress to the level of a new born, and so potentially could reduce disease and increase longevity. I looked in the messages and didn't see anyone react to this unless I missed it. Too bad he is just beginning testing now. It will not require FDA approval because it has herbal ingredients, 5 of them of which green tea and turmeric are the best known, which I already use as much as possible. I think they are putting it on the market rapidly since there is nothing noxive in the ingredients. I am very limited in my knowledge but thought i would bring this up if anyone wants to check the health section of ABC.com, seems promising, and would be interested if anyone has any comments, if this is new or an old subject, or seems likely to keep us all looking flush like new babies at 85 or 95? __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 7, 2005 Report Share Posted June 7, 2005 Hi : Sorry to join the chorus here. But try this: Go to Pubmed and enter " protandim " in the little box, and hit enter. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed How many studies does it come up with? ZERO. Now ask yourself, if no studies of this supposedly miracle cure have passed muster to be included in Pubmed, then where on earth did the promoters of this concoction get their information? Answer: Their PR department, most likely. Let them find one study, done by serious scientists, supporting their conclusions, in fruit flies or mice or monkeys or humans, and I will sit up and take notice. Three studies, and with none showing worrying side-effects, and I will start taking it. Rodney. --- In , Short <ottawan50@y...> wrote: > > > I was watching ABC health news on tv, on June 2 and saw a really interesting interview with Dr Joe McCord. He has developed I think and is to begin testing and marketing a little yellow pill called Protandim. He claims that it reduces oxidative stress to the level of a new born, and so potentially could reduce disease and increase longevity. I looked in the messages and didn't see anyone react to this unless I missed it. Too bad he is just beginning testing now. It will not require FDA approval because it has herbal ingredients, 5 of them of which green tea and turmeric are the best known, which I already use as much as possible. I think they are putting it on the market rapidly since there is nothing noxive in the ingredients. I am very limited in my knowledge but thought i would bring this up if anyone wants to check the health section of ABC.com, seems promising, and would be interested if anyone has any comments, if this is new or an old subject, or seems likely to keep us all > looking flush like new babies at 85 or 95? > > > > > > > > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 7, 2005 Report Share Posted June 7, 2005 Hi All, From: http://www.fightaging.org/archives/000502.php Reason may be right to say: It seems that Lifeline Therapeutics, marketeer for Protandim, has netted venture capital: Lifeline Therapeutics, Inc. (OTCBB: LFLT), a health company dedicated to developing products that help people live better, healthier and longer lives by fighting oxidative damage in the body, today announced the company completed an $8 million private placement. Keating Securities, LLC acted as sole placement agent of the financing. Proceeds from this funding will be used to eliminate the Company's debt of $3 million, for U.S. research surrounding its Protandim product and as working capital related to the development of new antioxidant therapies. Through the miracle of product placement - available to those bearers of the magic green tokens we call " money " - this coincides with a nice healthy examination of Protandim and supporting science at ABC. Such is the way the world works, nothing out of the ordinary there. What makes me a little more skeptical than normal when it comes to pills and anti-aging claims is the history of this particular company. The short version can be told as follows: CereMedix tests a compound that could extend life span by mitigating oxidative stress. This is CMX-1152, described on the CereMedix website (scroll down a bit on that page). Lifeline is founded on the basis of a licensing deal with CereMedix; the Protandim name is later assigned to CMX-1152 Around this time, I begin to comment on this deal, CMX-1152, Protandim and Lifeline. Some of my comments are promptly misquoted, rewritten and used as a glowing endorsement on the Lifeline website; not an auspicious start. My grumbling on that topic can be seen in the Immortality Institute thread on Lifeline. For reasons that remain unclear, Lifeline does not proceed with CMX-1152, but rather begins looking for a new product to market under the existing brand name of Protandim. For a time, Lifeline continues to use the experimental results from CMX-1152 to tout their new non-CMX-1152 product, which could charitably be described as a potpourri of existing antioxidant supplements. This also is documented in the the Immortality Institute thread on Lifeline. Not cricket, gentlemen. Now we see a more mature offering from Lifeline, at least in the marketing department. They have retained the focus on oxidative stress, but are building a brand on the work of different scientists. So far as it goes, it looks like Lifeline is still selling the potpourri of existing supplements. So, this is just like the circus over resveratrol by the looks of things; some moderately interesting science in the intersection of metabolism and longevity buried by a cartload of marketing. We may, or may not, find out something interesting about the long term effects of the product on humans in a decade or so. As for resveratrol, I have no doubt some folks will make money from Protandim, but this is a distracting sideshow for anyone interested in meaningful healthy life extension. The immediate future of health and longevity is not in pills, folks. There isn't anything out there proven to do better than simple calorie restriction - and even that isn't so great in the grand scheme of what is possible. If you want to live a much longer, much healthier life, don't spend all your time chasing after better pills and tinkering with your metabolism. Instead put your energies into supporting the sort of research that will put an end to age-related degeneration once and for all - that could happen within our lifetime, but only if we stand up and make sure of it. UPDATE: Some interesting comments from Pete Estrep: Well, they certainly have guts to present the data on this web page, http://www.protandim.com/scientific-studies.htm Around thirty mice and thirteen subjects in the human trial. They draw a line through points that have an R^2 of 0.02. This means that the points are almost randomly scattered. Sure, you can draw a line through these points but it is almost meaningless. I won't be buying Protandim until they generate a lot more data. FYI, the stuff is made of herbs (ashwagandha, and extracts of milk thistle, bacopa, green tea, and turmeric). They claim it works by increasing levels of protein antioxidants. If this is true I am interested in the mechanism since you can increase levels of endogenous antioxidants by increasing oxidative stress and damage. This is similar to certain claims of compounds increasing levels of DNA repair enzymes. The most reliable way to do this is to increase DNA damage because you will get elevated levels of repair enzymes in response to damage. The effect Protandim has on lipid peroxidation is irrelevant since lipids are replaceable, it is just a proxy for damage to more precious stuff, like DNA.. What we really want to know is what Protandim does to the rate of DNA damage. Does it cause less damage, more, no change? Unknown. Posted by Reason at June 3, 2005 12:07 AM --- Short <ottawan50@...> wrote: > I was watching ABC health news on tv, on June 2 and saw a really interesting > interview with Dr Joe McCord. He has developed I think and is to begin testing and > marketing a little yellow pill called Protandim. He claims that it reduces > oxidative stress to the level of a new born, and so potentially could reduce > disease and increase longevity. I looked in the messages and didn't see anyone > react to this unless I missed it. Too bad he is just beginning testing now. It > will not require FDA approval because it has herbal ingredients, 5 of them of > which green tea and turmeric are the best known, which I already use as much as > possible. I think they are putting it on the market rapidly since there is nothing > noxive in the ingredients. I am very limited in my knowledge but thought i would > bring this up if anyone wants to check the health section of ABC.com, seems > promising, and would be interested if anyone has any comments, if this is new or > an old subject, or seems likely to keep us all > looking flush like new babies at 85 or 95? Al Pater, PhD; email: old542000@... __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 7, 2005 Report Share Posted June 7, 2005 Alternatively, try some of its components separately in pubmed and you'll surely get results, i.e., milk thistle, turmeric, etc.. - --- In , " Rodney " <perspect1111@y...> wrote: > Hi : > > Sorry to join the chorus here. But try this: Go to Pubmed and > enter " protandim " in the little box, and hit enter. > > http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed > > How many studies does it come up with? > > ZERO. > > Now ask yourself, if no studies of this supposedly miracle cure have > passed muster to be included in Pubmed, then where on earth did the > promoters of this concoction get their information? > > Answer: Their PR department, most likely. > > Let them find one study, done by serious scientists, supporting their > conclusions, in fruit flies or mice or monkeys or humans, and I will > sit up and take notice. Three studies, and with none showing > worrying side-effects, and I will start taking it. > > Rodney. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 15, 2005 Report Share Posted November 15, 2005 As many of you will recall, I tried Protandim for a few months after seeing Dateline and how promising the product seemed for reducing oxidative stress levels. I stopped taking it after lab work showed that after over two months, my oxidative stress level not only did not improve, it was a bit higher! Today I received a phone call from a scientist from Protandim who told me that I am the only person that Protandim did not help. They asked me to fax my lab work to them so they could see why it didn't help me or if the lab work I had wasn't conclusive. I am impressed that they are actually concerned that their product didn't help one person. The main doctor is supposed to either phone or email me after he has had a chance to look at my labs. I thought I'd pass this information on since I am the only person on record who was not helped by Protandim. It may be worth it for others to give the product a try. Kenda Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 15, 2005 Report Share Posted November 15, 2005 Hmmm, sounds alot like the plastic surgeons who say to so many of our girls, " You are the only patient I've had who has complained about their implants " ! That is unfortunate that you went through that and didn't see any improvements. I wonder if anyone else here has tried it and gotten lab results to prove what is happening? Glad you were on top of this Kenda. I guess it can be a good thing being a test junkie! I hope you hear back from them about this. Patty --- In , Kenda Skaggs <skaggs@c...> wrote: > > As many of you will recall, I tried Protandim for a few months after seeing > Dateline and how promising the product seemed for reducing oxidative stress > levels. I stopped taking it after lab work showed that after over two > months, my oxidative stress level not only did not improve, it was a bit > higher! Today I received a phone call from a scientist from Protandim who > told me that I am the only person that Protandim did not help. They asked me > to fax my lab work to them so they could see why it didn't help me or if the > lab work I had wasn't conclusive. I am impressed that they are actually > concerned that their product didn't help one person. The main doctor is > supposed to either phone or email me after he has had a chance to look at my > labs. > > I thought I'd pass this information on since I am the only person on record > who was not helped by Protandim. It may be worth it for others to give the > product a try. > > Kenda > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 15, 2005 Report Share Posted November 15, 2005 Believe it or not, I believed her when she told me that they have a 100% success rate. They seemed genuinely concerned that I didn't respond to their product and why and took the time to phone me. I was impressed that a scientist phoned me, not an office worker. We'll see what becomes of it. If they don't contact me again, I'll side with you. I'd love to try their product at their expense this time and let them pay for my next labs! Kenda > Hmmm, sounds alot like the plastic surgeons who say to so many of > our girls, " You are the only patient I've had who has complained > about their implants " ! > > That is unfortunate that you went through that and didn't see any > improvements. I wonder if anyone else here has tried it and gotten > lab results to prove what is happening? > > Glad you were on top of this Kenda. I guess it can be a good thing > being a test junkie! I hope you hear back from them about this. > Patty > > >> >> As many of you will recall, I tried Protandim for a few months > after seeing >> Dateline and how promising the product seemed for reducing > oxidative stress >> levels. I stopped taking it after lab work showed that after over > two >> months, my oxidative stress level not only did not improve, it was > a bit >> higher! Today I received a phone call from a scientist from > Protandim who >> told me that I am the only person that Protandim did not help. > They asked me >> to fax my lab work to them so they could see why it didn't help me > or if the >> lab work I had wasn't conclusive. I am impressed that they are > actually >> concerned that their product didn't help one person. The main > doctor is >> supposed to either phone or email me after he has had a chance to > look at my >> labs. >> >> I thought I'd pass this information on since I am the only person > on record >> who was not helped by Protandim. It may be worth it for others to > give the >> product a try. >> >> Kenda >> > > > > > > > Opinions expressed are NOT meant to take the place of advice given by licensed > health care professionals. Consult your physician or licensed health care > professional before commencing any medical treatment. > > " Do not let either the medical authorities or the politicians mislead you. > Find out what the facts are, and make your own decisions about how to live a > happy life and how to work for a better world. " - Linus ing, two-time > Nobel Prize Winner (1954, Chemistry; 1963, Peace) > > See our photos website! Enter " implants " for access at this link: > http://.shutterfly.com/action/ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 15, 2005 Report Share Posted November 15, 2005 You are the only person they SAID has not responded. I guess I am just cynical... but I don't believe the line " you are the only person... " Perhaps others didn't complain. > > > > As many of you will recall, I tried Protandim for a few months > after seeing > > Dateline and how promising the product seemed for reducing > oxidative stress > > levels. I stopped taking it after lab work showed that after over > two > > months, my oxidative stress level not only did not improve, it was > a bit > > higher! Today I received a phone call from a scientist from > Protandim who > > told me that I am the only person that Protandim did not help. > They asked me > > to fax my lab work to them so they could see why it didn't help me > or if the > > lab work I had wasn't conclusive. I am impressed that they are > actually > > concerned that their product didn't help one person. The main > doctor is > > supposed to either phone or email me after he has had a chance to > look at my > > labs. > > > > I thought I'd pass this information on since I am the only person > on record > > who was not helped by Protandim. It may be worth it for others to > give the > > product a try. > > > > Kenda > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 16, 2005 Report Share Posted November 16, 2005 Exactly, it leaves a lot of room for speculation. Not everyone does complain. It's like the doctor that believes they have cured all of their patients because they don't come back. The proof will be in how far they take this with me. I faxed my lab reports, well see where it goes from here. Kenda > You are the only person they SAID has not responded. > I guess I am just cynical... but I don't believe the line " you are the only > person... " > Perhaps others didn't complain. > > >>> >>> As many of you will recall, I tried Protandim for a few months >> after seeing >>> Dateline and how promising the product seemed for reducing >> oxidative stress >>> levels. I stopped taking it after lab work showed that after over >> two >>> months, my oxidative stress level not only did not improve, it was >> a bit >>> higher! Today I received a phone call from a scientist from >> Protandim who >>> told me that I am the only person that Protandim did not help. >> They asked me >>> to fax my lab work to them so they could see why it didn't help me >> or if the >>> lab work I had wasn't conclusive. I am impressed that they are >> actually >>> concerned that their product didn't help one person. The main >> doctor is >>> supposed to either phone or email me after he has had a chance to >> look at my >>> labs. >>> >>> I thought I'd pass this information on since I am the only person >> on record >>> who was not helped by Protandim. It may be worth it for others to >> give the >>> product a try. >>> >>> Kenda >>> >> > > > > > > > Opinions expressed are NOT meant to take the place of advice given by licensed > health care professionals. Consult your physician or licensed health care > professional before commencing any medical treatment. > > " Do not let either the medical authorities or the politicians mislead you. > Find out what the facts are, and make your own decisions about how to live a > happy life and how to work for a better world. " - Linus ing, two-time > Nobel Prize Winner (1954, Chemistry; 1963, Peace) > > See our photos website! Enter " implants " for access at this link: > http://.shutterfly.com/action/ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 16, 2005 Report Share Posted November 16, 2005 Wow, kenda I am rather impressed too! Are you going to send them your lab test results? Do you think that you might be interested in giving it another shot? What does Dr. Leu think? kathy --- In , Kenda Skaggs <skaggs@c...> wrote: > > As many of you will recall, I tried Protandim for a few months after seeing > Dateline and how promising the product seemed for reducing oxidative stress > levels. I stopped taking it after lab work showed that after over two > months, my oxidative stress level not only did not improve, it was a bit > higher! Today I received a phone call from a scientist from Protandim who > told me that I am the only person that Protandim did not help. They asked me > to fax my lab work to them so they could see why it didn't help me or if the > lab work I had wasn't conclusive. I am impressed that they are actually > concerned that their product didn't help one person. The main doctor is > supposed to either phone or email me after he has had a chance to look at my > labs. > > I thought I'd pass this information on since I am the only person on record > who was not helped by Protandim. It may be worth it for others to give the > product a try. > > Kenda > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 16, 2005 Report Share Posted November 16, 2005 Hi Kathy, I faxed my labs to them yesterday afternoon and am waiting to hear back from the lead doctor. I would give it another try if they were willing to pay for some of the lab work. I figure they have as much to gain by proving the product works as I do. I haven't told Dr. Leu yet, I am waiting to see what Protandim does next. Kenda > > Wow, kenda > I am rather impressed too! Are you going to send them your lab test > results? Do you think that you might be interested in giving it > another shot? What does Dr. Leu think? > kathy > > > > > > > > >> >> As many of you will recall, I tried Protandim for a few months > after seeing >> Dateline and how promising the product seemed for reducing > oxidative stress >> levels. I stopped taking it after lab work showed that after over > two >> months, my oxidative stress level not only did not improve, it was > a bit >> higher! Today I received a phone call from a scientist from > Protandim who >> told me that I am the only person that Protandim did not help. > They asked me >> to fax my lab work to them so they could see why it didn't help me > or if the >> lab work I had wasn't conclusive. I am impressed that they are > actually >> concerned that their product didn't help one person. The main > doctor is >> supposed to either phone or email me after he has had a chance to > look at my >> labs. >> >> I thought I'd pass this information on since I am the only person > on record >> who was not helped by Protandim. It may be worth it for others to > give the >> product a try. >> >> Kenda >> > > > > > > > Opinions expressed are NOT meant to take the place of advice given by licensed > health care professionals. Consult your physician or licensed health care > professional before commencing any medical treatment. > > " Do not let either the medical authorities or the politicians mislead you. > Find out what the facts are, and make your own decisions about how to live a > happy life and how to work for a better world. " - Linus ing, two-time > Nobel Prize Winner (1954, Chemistry; 1963, Peace) > > See our photos website! Enter " implants " for access at this link: > http://.shutterfly.com/action/ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2010 Report Share Posted September 12, 2010 One of the mothers on the GFCF recipes group used it with her kids and found it helpful. Unfortunately it has milk thistle and tumeric, so we cant use it. Karla > > Has anyone here used this? It's supposed to increase glutathione by 300% to aide in methylation/sulfation. The advertising looks great but personal experience says soooo much more.... > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 12, 2010 Report Share Posted September 12, 2010 not yet. Someone asked me about it, I looked it up and only found the advertising, which of course makes it look like a miracle cure. nancy j a child is diagnosed with asd every 20 seconds From: ideals04 <ideals04@...> Subject: [ ] Re: protandim Date: Sunday, September 12, 2010, 6:23 PM  Have you chelated? > > Has anyone here used this? It's supposed to increase glutathione by 300% to aide in methylation/sulfation. The advertising looks great but personal experience says soooo much more.... > Quote Link to comment Share on other sites More sharing options...
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