Re: Re: Problems with Aspirin in Older People?

[Guest guest]

I believe there are blood tests that can gauge your general inflammation level.

If it's high, like most overweight with poor diets NSAIDs will probably help.

However if it's already low thanks to low energy balance and good N3/N6 ratios

you could drive it too low, perhaps compromising healing and immune responses.

I repeat my caution about applying general remedies to specific cases.

JR

-----Original Message-----

From:

[mailto: ]On Behalf Of Rodney

Sent: Friday, May 20, 2005 10:32 AM

Subject: [ ] Re: Problems with Aspirin in Older People?

Hi JR:

Yes. In principle I agree with you. Avoid (almost) all medications

unless ABSOLUTELY necessary. However I have made an exception in the

case of aspirin because of its multiple, apparent, benefits, many of

which have been attributed to its anti-inflammatory characteristics.

And of course we know that more and more problems are now being

traced to inflammation.

These benefits include a significant reduction in colon cancer risk

and a smaller reduction in prostate cancer risk.

(Does aspirin qualify as an NSAID? If so, one study attributed a 66%

reduction in prostate cancer incidence to taking NSAIDs.)

So even if we do not need to be concerned with CVD, there may be good

reason to take aspirin for other benefits.

OTOH since aspirin may contribute to hemorrhagic strokes - the type

CR people are more likely to get, that may be a special risk we need

to be cautious about.

Rodney.

--- In , " " <crjohnr@b...>

wrote:

> This sounds like common sense. I thought low dose aspirin

was " only " advocated

> for people with previous heart attacks or known problems.

>

> If we eat less and live right.... foods, drugs, supplements, etc

that prove helpful to

> sedentary, overweight, and malnutrite, may be either useless or

perhaps dangerous to

> us.

>

> The vast majority of popular research may not be very applicable to

our lifestyles.

> This one sounds an IMO useful warning. I suggest recent questions

about statins etc, may

> fall into the same category.

>

> Be well,

>

> JR

>

> -----Original Message-----

> From:

> [mailto: ]On Behalf Of Rodney

> Sent: Friday, May 20, 2005 8:17 AM

>

> Subject: [ ] Problems with Aspirin in Older People?

>

>

> http://news.bbc.co.uk/2/hi/health/4561573.stm

>

> Rodney.

[Guest guest]

But, /Rodney, we are using a remedy to avoid aging, called CR.

If I believe the blood tests, then I must act on the chemical to counteract the problem.

Fortunately, or unfortunately, most blood tests don't tell me much.

Some also use supplements. I see no diff in a supplement versus a drug - used to cure, treat or prevent a problem. The problem is not knowing what to do. I can't adopt a strategy of generally avoiding medications. That would be risky.

So do I duck lycopene, eg?

A book by Pearson on life extension, 1986, looks quite silly to me today - silly enough I trashed it. New strategies and analyses emerge daily and I agree that we use moderation in adopting anything in conjunction with CR, since we really don't know that much about CR or interactions.

FWIW, CR alone made major changes in my health, activity level, and requirement for medications.

Regards.

----- Original Message -----

From:

Sent: Friday, May 20, 2005 11:03 AM

Subject: RE: [ ] Re: Problems with Aspirin in Older People?

I believe there are blood tests that can gauge your general inflammation level.If it's high, like most overweight with poor diets NSAIDs will probably help. However if it's already low thanks to low energy balance and good N3/N6 ratios you could drive it too low, perhaps compromising healing and immune responses.I repeat my caution about applying general remedies to specific cases.JR-----Original Message-----From: [mailto: ]On Behalf Of RodneySent: Friday, May 20, 2005 10:32 AM Subject: [ ] Re: Problems with Aspirin in Older People?Hi JR:Yes. In principle I agree with you. Avoid (almost) all medications unless ABSOLUTELY necessary. However I have made an exception in the case of aspirin because of its multiple, apparent, benefits, many of which have been attributed to its anti-inflammatory characteristics. And of course we know that more and more problems are now being traced to inflammation.These benefits include a significant reduction in colon cancer risk and a smaller reduction in prostate cancer risk. (Does aspirin qualify as an NSAID? If so, one study attributed a 66% reduction in prostate cancer incidence to taking NSAIDs.)So even if we do not need to be concerned with CVD, there may be good reason to take aspirin for other benefits.OTOH since aspirin may contribute to hemorrhagic strokes - the type CR people are more likely to get, that may be a special risk we need to be cautious about.Rodney.

[Guest guest]

Application of a specific drug/supplement/whatever to manage a known measured bio-marker that's out of line sounds

like an intelligent behavior. Using general advice targeted at a different general population, using metrics that may not

even be appropriate to us (specifically because of CR), does not sound wise.

I gather from your many posts that you are very analytical and not inclined to take supplements because they're

fashionable. However some (and I'm not singling anybody out) are still programmed by the Dr. Welby image of take a pill,

then get better, as the answer to everything. Life is a bit more complex than that. :-)

I take aspirin when I get a headache, but funny thing... I haven't had a headache in years. (In fact I did dose up on

aspirin a few years ago when I had a traveling blood clot from a sports injury. I was too cheap/stupid to find

a Dr. who would have probably prescribed wafarin @ 100x the cost, and a day too late).

Life is good. Be well.

JR

-----Original Message-----From: [mailto: ]On Behalf Of jwwrightSent: Friday, May 20, 2005 11:30 AM Subject: Re: [ ] Re: Problems with Aspirin in Older People?

But, /Rodney, we are using a remedy to avoid aging, called CR.

If I believe the blood tests, then I must act on the chemical to counteract the problem.

Fortunately, or unfortunately, most blood tests don't tell me much.

Some also use supplements. I see no diff in a supplement versus a drug - used to cure, treat or prevent a problem. The problem is not knowing what to do. I can't adopt a strategy of generally avoiding medications. That would be risky.

So do I duck lycopene, eg?

A book by Pearson on life extension, 1986, looks quite silly to me today - silly enough I trashed it. New strategies and analyses emerge daily and I agree that we use moderation in adopting anything in conjunction with CR, since we really don't know that much about CR or interactions.

FWIW, CR alone made major changes in my health, activity level, and requirement for medications.

Regards.