The occurrence of multiple myeloma and chronic lymphocytic leukemia in the same patient is very uncommon. The immunomodulatory agent lenalidomide has been shown to have high response rates in multiple myeloma and appears to be quite active in advance

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Concurrent B-cell chronic lymphocytic leukemia and multiple myeloma treated

successfully with lenalidomide.

Sridhar Srinivasan and A Schiffer

Leuk Res, August 1, 2008; .

Division of Hematology/Oncology, Karmanos Cancer Institute, Wayne State

University School of Medicine, HWCRB-4th Floor, 4100 R, Detroit, MI 48201,

USA.

The occurrence of multiple myeloma and chronic lymphocytic leukemia in the same

patient is very uncommon. The immunomodulatory agent lenalidomide has been shown

to have high response rates in multiple myeloma and appears to be quite active

in advanced CLL. We report two patients with concurrent CLL and MM who were both

treated successfully with lenalidomide.

PMID: 18676017