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Of mice and CR: not all genotypes respond favorably

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in Health, Medicine and Natural Healing 05

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Just some food for thought to go along with all that garlic: In a

FASEB article

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstra\

ct & list_uids=12586746 & query_hl=6

Forster et al. demonstrate that in certain genotypic backgrounds, CR

fails to increase longevity. These authors also note that in certain

genotypes (DBA/2 in this instance) CR imposed late in life decreases

rather than increases longevity.

By extention, one might predict that some humans, like the DBA/2 mice

in the study, will prove to be rather insensitive to CR.

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