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Re: Pulse Pressure

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Since I seem to have a " wide " pulse pressure, what can I do about it? I weigh a scant 110lbs (down a few pounds from 113 or so). Searched the web and nothing specific for lowering PP shows up.

on 7/26/2005 10:55 AM, Jeff Novick at jnovick@... wrote:

JR brought this issue up and thought I would post a few references to it...

Blood Press. 2000;9(5):260-6. Related Articles, Links

Pulse pressure: a predictor of cardiovascular mortality among young normotensive subjects.

Fang J, Madhavan S, Alderman MH.Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, New York, Bronx 10461, USA. fang@...

In conclusion, among young subjects, but not older normotensive persons, at very low risk of cardiovascular disease, a wide pulse pressure is associated with increased cardiovascular mortality.

PMID: 11193129

Hypertension. 1997 Dec;30(6):1410-5.

Pulse pressure: a predictor of long-term cardiovascular mortality in a French male population.

Benetos A, Safar M, Rudnichi A, Smulyan H, JL, Ducimetieere P, Guize L.

Investigations Preventives et Cliniques, Paris, France.

In conclusion, in a large population of men with a relatively low cardiovascular risk, a wide pulse pressure is a significant independent predictor of all-cause, cardiovascular, and, especially, coronary mortality.

PMID: 940356

Clin Cardiol. 2003 Feb;26(2):91-7.

Systolic, diastolic, and pulse pressures as coronary risk factors in a population with low cholesterol levels: a prospective 10-year evaluation.

Onat A, Ceyhan K, Erer B, Basar O, Uysal O, Sansoy V.Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey. tkd@...

CONCLUSION: Although inferior to the predictive power of SBP, PP was an important determinant of CHD risk in a population of a diverse age span and a better predictor than DBP in men.

PMID: 12625600

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High Pulse Pressure (PP) is associated with risk of heart disease.

http://www.mercola.com/2000/jun/17/pulse_pressure.htm

One of the notes on this topic mentioned that high pulse pressure is

caused by lack of pliability of the arteries (arterial stiffness).

The high PP is caused when the stiff arteries are not able to collapse

when the heart is not pumping and the diastolic pressure becomes lower

than it would be if the arteries were able to collapse easily.

The question is how can this arterial stiffness be improved? To

answer this question you have to know what are the constituents of the

arterial walls. See for example:

http://circ.ahajournals.org/cgi/content/full/96/1/99

Circulation. 1997;96:99-105.

Determination of Human Coronary Artery Composition by Raman Spectroscopy

It turns out that some of the components of arterial cellular

structure that alter flexibility are the lipids (cholesterol esters,

triglycerides and phospholipids). Triglycerides with greater

saturation will have a higher melting point and will be stiffer than

triglycerides that are more unsaturated and have a lower melting point.

Maybe a diet deficient in omega-6, omega-3, and other polyunsturated

fatty acids results in stiffer arteries?

Tony

> >

> > > BP (was: : Salt consumption)There is also a third metric " pulse

> pressure "

> > > which is the difference between the two. 120/80 is considered

> > > normal, with a 40 pulse pressure. I have no idea how healthy

> normal is. I

> > > suspect normal for

> > > energy restricted individuals may be lower. All three numbers

> apparently

> > > represent different concerns.

> > >

> > > My personal experience after losing much weight is that my BP fell

> > > considerably and my pulse rose slightly

> > > perhaps related? I just measured 103/73 p58 . This is not a low

> measurement

> > > for me but I don't monitor

> > > this closely since it dropped so far below supposedly normal

> targets.

> > >

> > > JR

> > > -----Original Message-----

> >

> >

> > Al Pater, PhD; email: old542000@y...

> >

> > __________________________________________________

> >

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