Re: Food advanced glycation end products toxic?

[Guest guest]

Another view of AGE in that the ls of the NY Academy of Science--

Ann N Y Acad Sci. 2005 Jun;1043:461-6

Diet-Derived Advanced Glycation End Products Are Major Contributors

to the Body's AGE Pool and Induce Inflammation in Healthy Subjects.

Uribarri J, Cai W, Sandu O, Peppa M, Goldberg T, Vlassara H.

PMID: 16037267 [PubMed - in process]

http://tinyurl.com/c5nus

Advanced glycation end products (AGEs) are a heterogeneous group of

compounds that form continuously in the body. Their rate of

endogenous formation is markedly increased in diabetes mellitus, a

condition in which AGEs play a major pathological role. It is also

known, however, that AGEs form during the cooking of foods,

primarily as the result of the application of heat. This review

focuses on the generation of AGEs during the cooking of food, the

gastrointestinal absorption of these compounds, and their biological

effects in vitro and in vivo. We also present preliminary evidence

of a direct association between dietary AGE intake and markers of

systemic inflammation such as C-reactive protein in a large group of

healthy subjects. Together with previous evidence from diabetics and

renal failure patients, these data suggest that dietary AGEs may

play an important role in the causation of chronic diseases

associated with underlying inflammation.

Mike

--- In , Al Pater <old542000@y...>

wrote:

> Hi All,

>

> Re:

>

> Chuyen NV, Arai H, Nakanishi T, Utsunomiya N.

> Are food advanced glycation end products toxic in biological

systems?

> Ann N Y Acad Sci. 2005 Jun;1043:467-73.

> PMID: 16037268

>

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=16037268 & query_hl=38

>

> The answer to " Are food advanced glycation end products toxic in

biological

> systems? " seems to be " " food AGEs are not toxic in biological

systems, and reactive

> oxygen species increase in diabetic rats is not caused by glycated

proteins but by

> other pathways. "

>

> The pdf is available.

>

> Al Pater, PhD; email: old542000@y...

>

>

>

> ____________________________________________________

> Start your day with - make it your home page

> http://www./r/hs

[Guest guest]

This sort of makes the case for the " raw foods " proponents. Thank

goodness I eat a lot of salads.

Diane

> > Hi All,

> >

> > Re:

> >

> > Chuyen NV, Arai H, Nakanishi T, Utsunomiya N.

> > Are food advanced glycation end products toxic in biological

> systems?

> > Ann N Y Acad Sci. 2005 Jun;1043:467-73.

> > PMID: 16037268

> >

> > http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

> cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=16037268 & query_hl=38

> >

> > The answer to " Are food advanced glycation end products toxic in

> biological

> > systems? " seems to be " " food AGEs are not toxic in biological

> systems, and reactive

> > oxygen species increase in diabetic rats is not caused by glycated

> proteins but by

> > other pathways. "

> >

> > The pdf is available.

> >

> > Al Pater, PhD; email: old542000@y...

> >

> >

> >

> > ____________________________________________________

> > Start your day with - make it your home page

> > http://www./r/hs