Higher than 30% fat means no change in mortality?

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Not only did high-fat diets not increase mortality, but saturated fat was similiarly unable to make mortality levels change appreciably. The only advere effect suggested from their analysis was the elevated breast cancer risk in women consuming the very highest amounts of fat....

I have a rather dim view of statistical work, but, nonetheless, these guys influence the debate.......

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J Intern Med. 2005 Aug;258(2):153-65.

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Dietary fat intake and early mortality patterns - data from The Malmo Diet and Cancer Study.Leosdottir M, Nilsson PM, Nilsson JA, Mansson H, Berglund G.From the Department of Medicine, Lund University, University Hospital (UMAS), Malmo, Sweden.Abstract. Leosdottir M, Nilsson PM, Nilsson J-A, Mansson H, Berglund G (Lund University, Malmo, Sweden). Dietary fat intake and early mortality patterns - data from The Malmo Diet and Cancer Study. J Intern Med 2005; 258: 153-165.Objectives. Most current dietary guidelines encourage limiting relative fat intake to <30% of total daily energy, with saturated and trans fatty acids contributing no more than 10%. We examined whether total fat intake, saturated fat, monounsaturated, or polyunsaturated fat intake are independent risk factors for prospective all-cause, cardiovascular and cancer mortality. Design. Population-based, prospective cohort study. Setting and subjects. The Malmo Diet and Cancer Study was set in the city of Malmo,

southern Sweden. A total of 28 098 middle-aged individuals participated in the study 1991-1996. Main outcome measures. Subjects were categorized by quartiles of relative fat intake, with the first quartile used as a reference point in estimating multivariate relative risks (RR; 95% CI, 's regression model). Adjustments were made for confounding by age and various lifestyle factors. Results. Women in the fourth quartile of total fat intake had a significantly higher RR of cancer mortality (RR 1.46; CI 1.04-2.04). A significant downwards trend was observed for cardiovascular mortality amongst men from the first to the fourth quartile (P = 0.028). No deteriorating effects of high saturated fat intake were observed for either sex for any cause of death. Beneficial effects of a relatively high intake of unsaturated fats were not uniform. Conclusions. With the exception of cancer mortality for women, individuals receiving more than 30% of their total daily energy from fat and more than

10% from saturated fat, did not have increased mortality. Current dietary guidelines concerning fat intake are thus generally not supported by our observational results.PMID: 16018792 [PubMed - in process]

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=16018792

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