Vaccine PSUs closure in India: info on PII Coonoor

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Following information on Pastuer Institute of India Coonoor is copied for fare use and is also available on this link given below.

http://www.pasteurinstituteindia.com/home.htm

About UsPasteur Institute of India, Coonoor is one of the leading Institute in the production of Anti-rabies Vaccine for the Expanded Programme of Immunization of Govt. of India. This Institute started functioning as Pasteur Institute of Southern India, on April 6, 1907 and the Institute took a new birth as the Pasteur Institute of India (registered as a society under the Societies Registration Act 1860) and started functioning as an autonomous body under the Ministry of Health and Family Welfare, Government of India, New Delhi from the February 10, 1977. The affairs of the institute are managed by a governing

body.The institute is a charitable organization working on no profit - no loss basis. Right to Information Act a) Name and Designation with Telephone No. of Officer appointed as Central Public Information Officer(CPIO) of Pasteur Institute of India, Coonoor Dr. N. Elangeswaran Director Pasteur Institue of Inida, Coonoor, 643103, Nilgiris Tel. No. 0423-2231250, 2231846 Appellate Authority The Secretary to Govt of India, authority of Health and Family Welfare, New Delhi 110011 (Ex- Office chairman of the Governing Body of Pasteur Institute of India, Coonoor)

TechnologyWe have consistently set the pace in innovating and adapting technology to suit Indian conditions and needs. It is this vast experience and expertise which makes it well equipped to meet the challenges of applying advanced technology in vaccine production. Among the major equipments available in the Institute are large bacterial fermentors, Zonal ultra centrifuge, freeze drier, several bulk autoclaves, Hot-air ovens, filling machines, large cold rooms and deep freezers etc. Full fledged facility is available for Research and Development work which includes radioisotope handling and all related equipments FPLC system, ultra centrifuge, ELISA reader and equipment for molecular biology work.The Institute is recognized by the Tamilnadu Dr. M. G. R. Medical University, Madras for M.D degree in Microbiology and by the Bharathiyar University, Coimbatore for Ph.D. Degree in Microbiology in the faculty of Science.The Institute has a well -faciliated library also. The Library is one of the best libraries in the South India. It is a special library with limited number of essential books in the field of Vaccinology, Biotechnology, Pharmacology and Microbiology. For mot of the periodical titles, back volumes are available from 1950 and for few

1920 onwards. Many scientist and trainees from various institutions utilize the library facilities. The library has stocked with 4192 books and 12022 bound volumes, 16 International journals, 14 Indian Journals and WHO Publications (Global subscription).

Objectives & ActivitiesProduction DTP group vaccines. â— DPT Vaccine â— DT Vaccine â— TT Vaccine Vero Cell Derived Rabies Vaccine for Human use. Tissue culture Anti Rabies Vaccine for Animals. R & D Cost effective Tissue Culture Rabies

Vaccine. Tissue Culture based cost effective JE Vaccine. Training Programmes and Post-graduate activities. Consultancy services to Scientists of other Institutions within the country and abroad. Establishing of WHO Collaborating Centre for Training in rabies Vaccine Production and Quality Control. Academic Programmes ( Bharathiar University, Coimbatore for Ph.D and Tamilnadu, Dr. M. G. R. Medical University, Madras for M.D.) Cost Effective Newer Vaccines/Sera. Training in Vaccine manufacture/Biotechnology. Enterovirus laboratory for cold chain monitoring of Oral Polio Vaccine and surveillance of paralytic poliomyelitis; and Government Analyst for testing OPV.Other Activities Rabies Diagnostic Laboratory. Dog/Animal bite Treatment Centre (24 hours service for emergency cases). National Polio Laboratory for Surveillance of AFP Cases.

Milestones1907 Manufacture of Neural Tissue Antirabies Vaccine.1957 Isolation of Asian Flue Virus during the pandemic and development of Influenza vaccine against the same virus.1970 For the first time in India PII, Coonoor developed, produced and supplied BPL inactivated Rabies Vaccine, which made the treatment easier, cheaper with less dose, injections and side effects with a vaccine of increased potency.1970 For the first time in India, PII Coonoor developed and produced

indigenous Oral Polio Vaccine Trivalent (Sabin).1982 Production of DPT group of vaccines for the National Programme of Immunization.1988 Production of Tissue Culture Rabies Vaccine for Canine Prophylaxis, a milestone in the control of rabies.2001 For the first time in India PII, Coonoor, amongst Government controlled Institutions, developed and released Vero Cell Derived DNA purified Rabies Vaccine for human use at an affordable price to common man.

AchievementsResearch work on Rabies, Influenza, Adeno and other viruses, introduction of BPL inactivated brain tissue rabies vaccine for the first time in the country in the year 1970, production and release of more than one million doses of totally indigenous Oral Polio Vaccine, Substantial contribution of DTP Vaccines every year to the National Programme of Immunization and development of Vero Cell based vaccine for humans and canines by indigenous technology.The Institute’s dream is to be a model Institute with the introduction of modern processes and latest GMP facilities and be a leader in vaccinology in the country.

Future Plan Scaling up and providing cGMP facilities for the production of DPT group of Vaccines. Scaling up

and providing cGMP facilities for the production of Tissue Culture Antirabies Vaccine. Research and development of liquid tissue culture Rabies vaccine production to bring down the cost. Research and development of state of the art chromatorgraphy purification system to produce DNA free freeze dried

vaccine culture rabies vaccine. Research and development of newer cost effective vaccines like Quardruple vaccine (Hepatitis-B + DPT vaccine) and Vero cell derived inactivated purified Japanese Encephalitis vaccine for humans. New facilities

for production of newer Viral and Bacterial Vaccines with cGMP facilities and R & D at Coimbtore.

Regards,

Dr Kiran Chaudhari

Lecturer,

Dept of Pharmacology,

GMC, Nagpur

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