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Re: camelbelly disease

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Dear Sanjay,

Many thanks for your contribution, it was really interesting case study, and very nice isloation measures by the institute.

Hope you contribute more with us

Best Regards

Mohammad Bashaar

From: sanjay choudhari <sanjaych7@...>Subject: camelbelly diseasenetrum Date: Wednesday, July 2, 2008, 7:13 PM

status in INDIA

In kusmi block of SARGUJA district in MP ,during 1973 and again during 1976 ,an outbreak of rapidly devoloping ascites and jaundice ws reported among the Nagesia Tribals known as ENDEMIC ASCITES.

Age - All age groups involved except infants

Sex - Both sexes equally

Etiology - As per study conducted by National institute of nutrition ,Hyderabad-- local population subsist on millet PANICUM MILIARE (locally known as GONDHLI) which gets contaminated with weed seeds of CROTALARIA (locally known as JHUNJHUNIA )

Chemical analysis of Jhunjhunia found to contain PYRROLIZIDINE alkaloids which are hepatotoxins .

Preventive measures--

-- Educating the people in affected areas about the disese

--Deweeding of Jhunjhunia plants which grow along with staple

-- Simple sieving of millet at the household level to remove the seeds of jhunjhunia which are smaller than those of the millet

Bollywood, fun, friendship, sports and more. You name it, we have it.

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Dear friends,

Some years back, in India, there were cases of mustard oil poisoning caused by contamination of sanguiarine (I don't remember the exact spelling) seeds. Was that hepatic or renal toxicity?

-Anupama

From: sanjay choudhari <sanjaych7 (DOT) co.in>Subject: camelbelly diseasenetrumgroups (DOT) comDate: Wednesday, July 2, 2008, 7:13 PM

status in INDIA

In kusmi block of SARGUJA district in MP ,during 1973 and again during 1976 ,an outbreak of rapidly devoloping ascites and jaundice ws reported among the Nagesia Tribals known as ENDEMIC ASCITES.

Age - All age groups involved except infants

Sex - Both sexes equally

Etiology - As per study conducted by National institute of nutrition ,Hyderabad-- local population subsist on millet PANICUM MILIARE (locally known as GONDHLI) which gets contaminated with weed seeds of CROTALARIA (locally known as JHUNJHUNIA )

Chemical analysis of Jhunjhunia found to contain PYRROLIZIDINE alkaloids which are hepatotoxins .

Preventive measures--

-- Educating the people in affected areas about the disese

--Deweeding of Jhunjhunia plants which grow along with staple

-- Simple sieving of millet at the household level to remove the seeds of jhunjhunia which are smaller than those of the millet

Bollywood, fun, friendship, sports and more. You name it, we have it.

From Chandigarh to Chennai - find friends all over India. Click here.

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Dear Anupama,

Thanks for the information in fact. It is worth mentioing, that since morning this is the first posting from our esteemed colleagues.

Through this message, I request all members to take active part in this discussion and come up with your experiences and research knowledge that you have regarding charmak/gulran disease.

Best Regards

Mohammad Bashaar

From: sanjay choudhari <sanjaych7 (DOT) co.in>Subject: camelbelly diseasenetrumgroups (DOT) comDate: Wednesday, July 2, 2008, 7:13 PM

status in INDIA

In kusmi block of SARGUJA district in MP ,during 1973 and again during 1976 ,an outbreak of rapidly devoloping ascites and jaundice ws reported among the Nagesia Tribals known as ENDEMIC ASCITES.

Age - All age groups involved except infants

Sex - Both sexes equally

Etiology - As per study conducted by National institute of nutrition ,Hyderabad-- local population subsist on millet PANICUM MILIARE (locally known as GONDHLI) which gets contaminated with weed seeds of CROTALARIA (locally known as JHUNJHUNIA )

Chemical analysis of Jhunjhunia found to contain PYRROLIZIDINE alkaloids which are hepatotoxins .

Preventive measures--

-- Educating the people in affected areas about the disese

--Deweeding of Jhunjhunia plants which grow along with staple

-- Simple sieving of millet at the household level to remove the seeds of jhunjhunia which are smaller than those of the millet

Bollywood, fun, friendship, sports and more. You name it, we have it.

From Chandigarh to Chennai - find friends all over India. Click here.

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Hi Anupama and Bashaar,

Sanguinarine toxicity is predominantly cardiac and partly renal which leads to generalized edema and ascites (however unlike VOD due to PA the liver is spared). This is also called epidemic dropsy.

rakesh

On 7/3/08, Mohammad Bashaar <bashaarulfat@...> wrote:

Dear Anupama,

Thanks for the information in fact. It is worth mentioing, that since morning this is the first posting from our esteemed colleagues.

Through this message, I request all members to take active part in this discussion and come up with your experiences and research knowledge that you have regarding charmak/gulran disease.

Best Regards

Mohammad Bashaar

From: sanjay choudhari <sanjaych7 (DOT) co.in>Subject: camelbelly disease

netrumgroups (DOT) comDate: Wednesday, July 2, 2008, 7:13 PM

status in INDIA

In kusmi block of SARGUJA district in MP ,during 1973 and again during 1976 ,an outbreak of rapidly devoloping ascites and jaundice ws reported among the Nagesia Tribals known as ENDEMIC ASCITES.

Age - All age groups involved except infants

Sex - Both sexes equally

Etiology - As per study conducted by National institute of nutrition ,Hyderabad-- local population subsist on millet PANICUM MILIARE (locally known as GONDHLI) which gets contaminated with weed seeds of CROTALARIA (locally known as JHUNJHUNIA )

Chemical analysis of Jhunjhunia found to contain PYRROLIZIDINE alkaloids which are hepatotoxins .

Preventive measures--

-- Educating the people in affected areas about the disese

--Deweeding of Jhunjhunia plants which grow along with staple

-- Simple sieving of millet at the household level to remove the seeds of jhunjhunia which are smaller than those of the millet

Bollywood, fun, friendship, sports and more. You name it, we have it.

From Chandigarh to Chennai - find friends all over India. Click here.

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Also:

The earliest reference to argemone oil poisoning was made by Lyon (1889), who reported four cases of poisoning in Calcutta in 1877 from the use of this oil in food. Since then, Epidemic Dropsy has been reported from Bengal, Bihar, Orissa, Madhya Pradesh, Haryana, Assam, J & K, Uttar Pradesh, Gujarat, Delhi and Maharashtra, mainly due to consumption of food cooked in argemone oil mixed mustard oil or occasionally by body massage with contaminated oil.The epidemic in 1998 at New Delhi, India is the largest so far, in which over 60 persons lost their lives and more than 3000 victims were hospitalized (Das and Khanna, 1998). Even after that the epidemics occurred at alarming frequency in Gwalior (2000), Kannauj (2002) and Lucknow (2005) cities of India (Das et al, 2005).

On 7/3/08, Rakesh Biswas <rakesh7biswas@...> wrote:

Hi Anupama and Bashaar,

Sanguinarine toxicity is predominantly cardiac and partly renal which leads to generalized edema and ascites (however unlike VOD due to PA the liver is spared). This is also called epidemic dropsy.

rakesh

On 7/3/08, Mohammad Bashaar <bashaarulfat@...> wrote:

Dear Anupama,

Thanks for the information in fact. It is worth mentioing, that since morning this is the first posting from our esteemed colleagues.

Through this message, I request all members to take active part in this discussion and come up with your experiences and research knowledge that you have regarding charmak/gulran disease.

Best Regards

Mohammad Bashaar

From: sanjay choudhari <sanjaych7 (DOT) co.in>Subject: camelbelly disease

netrumgroups (DOT) comDate: Wednesday, July 2, 2008, 7:13 PM

status in INDIA

In kusmi block of SARGUJA district in MP ,during 1973 and again during 1976 ,an outbreak of rapidly devoloping ascites and jaundice ws reported among the Nagesia Tribals known as ENDEMIC ASCITES.

Age - All age groups involved except infants

Sex - Both sexes equally

Etiology - As per study conducted by National institute of nutrition ,Hyderabad-- local population subsist on millet PANICUM MILIARE (locally known as GONDHLI) which gets contaminated with weed seeds of CROTALARIA (locally known as JHUNJHUNIA )

Chemical analysis of Jhunjhunia found to contain PYRROLIZIDINE alkaloids which are hepatotoxins .

Preventive measures--

-- Educating the people in affected areas about the disese

--Deweeding of Jhunjhunia plants which grow along with staple

-- Simple sieving of millet at the household level to remove the seeds of jhunjhunia which are smaller than those of the millet

Bollywood, fun, friendship, sports and more. You name it, we have it.

From Chandigarh to Chennai - find friends all over India. Click here.

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Thanks Dr Rakesh.

Dear Dr Bashaar,

Other than the ones we have discussed, I couldn't get many references.

I am pasting a link of a news item I have gone through recently (hope i am permitted).

http://afghanronny.blogspot.com/2008/05/when-your-only-food-may-kill-you.html

-Anupama

From: sanjay choudhari <sanjaych7 (DOT) co.in>Subject: camelbelly diseasenetrumgroups (DOT) comDate: Wednesday, July 2, 2008, 7:13 PM

status in INDIA

In kusmi block of SARGUJA district in MP ,during 1973 and again during 1976 ,an outbreak of rapidly devoloping ascites and jaundice ws reported among the Nagesia Tribals known as ENDEMIC ASCITES.

Age - All age groups involved except infants

Sex - Both sexes equally

Etiology - As per study conducted by National institute of nutrition ,Hyderabad-- local population subsist on millet PANICUM MILIARE (locally known as GONDHLI) which gets contaminated with weed seeds of CROTALARIA (locally known as JHUNJHUNIA )

Chemical analysis of Jhunjhunia found to contain PYRROLIZIDINE alkaloids which are hepatotoxins .

Preventive measures--

-- Educating the people in affected areas about the disese

--Deweeding of Jhunjhunia plants which grow along with staple

-- Simple sieving of millet at the household level to remove the seeds of jhunjhunia which are smaller than those of the millet

Bollywood, fun, friendship, sports and more. You name it, we have it.

From Chandigarh to Chennai - find friends all over India. Click here.

Best Jokes, Best Friends, Best Food. Get all this and more on Best of .

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Dear Anupama,

I went through the pasted website, it was really informative. for sure, you have full permission.

Best Regards

Mohammad Bashaar

From: sanjay choudhari <sanjaych7 (DOT) co.in>Subject: camelbelly diseasenetrumgroups (DOT) comDate: Wednesday, July 2, 2008, 7:13 PM

status in INDIA

In kusmi block of SARGUJA district in MP ,during 1973 and again during 1976 ,an outbreak of rapidly devoloping ascites and jaundice ws reported among the Nagesia Tribals known as ENDEMIC ASCITES.

Age - All age groups involved except infants

Sex - Both sexes equally

Etiology - As per study conducted by National institute of nutrition ,Hyderabad-- local population subsist on millet PANICUM MILIARE (locally known as GONDHLI) which gets contaminated with weed seeds of CROTALARIA (locally known as JHUNJHUNIA )

Chemical analysis of Jhunjhunia found to contain PYRROLIZIDINE alkaloids which are hepatotoxins .

Preventive measures--

-- Educating the people in affected areas about the disese

--Deweeding of Jhunjhunia plants which grow along with staple

-- Simple sieving of millet at the household level to remove the seeds of jhunjhunia which are smaller than those of the millet

Bollywood, fun, friendship, sports and more. You name it, we have it.

From Chandigarh to Chennai - find friends all over India. Click here.

Best Jokes, Best Friends, Best Food. Get all this and more on Best of .

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