Guest guest Posted August 7, 2011 Report Share Posted August 7, 2011 Degradation is the continuous process; the meaning of degradation is not compound `A' is destroyed, but it mean compound `A' is converted into compound `C'. Example: Reaction A+ B= C A: Chemical `A' B: Any chemical or environmental condition. C: Any new unknown compound (Depending upon nature of reaction) Expiry date: we can decide expiry date of any formulation on the basis of stability studies. In which date the 10% amount of compound `A' is converted into compound `C' and only 90% if compound `A' is remain, called expire date. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 7, 2011 Report Share Posted August 7, 2011 Not sure if this is an appropriate time to respond (as a new topic is being discussed), the Australian Prescriber published a good readable report on drug expiry date issues that some of you may find helpful to read to form an opinion on the topic. I think the issue goes deeper than pharmaceutical company choices as to marketing and other consideration related to the marketability of individual medications. It may just as well be. However, like many other grey areas of evidence based medicine, this is another area where more systematic research to address the gap between " harm " as perceived on the basis of " biology " or " pharmacology " of a substance and its usage in the accepted norms of use in the society needs to be studied (and for individual drugs on condition basis). Here is the link to the article:http://www.australianprescriber.com/magazine/17/2/46/8Best,Arin Basu " There's a crack, a crack in everything.That's how the light gets in. " (Leonard Cohen) On Mon, Aug 8, 2011 at 4:45 AM, dipuparihar59 <dipuparihar59@...> wrote: Degradation is the continuous process; the meaning of degradation is not compound `A' is destroyed, but it mean compound `A' is converted into compound `C'. Example: Reaction A+ B= C A: Chemical `A' B: Any chemical or environmental condition. C: Any new unknown compound (Depending upon nature of reaction) Expiry date: we can decide expiry date of any formulation on the basis of stability studies. In which date the 10% amount of compound `A' is converted into compound `C' and only 90% if compound `A' is remain, called expire date. Quote Link to comment Share on other sites More sharing options...
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