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Respected members,I have attached an image a Promotional literature which shows Relative risk reduction and not Absolute risk reduction.Along with it, I have provided the original Lancet article of Caprie which shows the results of the original study.From this Promotional literature, I have explained the complete appraisal of a promotional literature

Check-list

Are the risks relative or absolute?

Relative.

Absolute = 0.51%

Is the result statistically

significant?

Yes.

P = .045 95% CI

Is the result clinically

significant?

No

NNT = 1/ARR =1/.005 =200

-Does the size of the

effect shown equal the size of the effect in the data? No

Are the references "real?â€

Yes, the “CAPRIE†study,

The Lancet, Vol. 348, November 16,1996.

Regards

Dr Sanjay Yallappa Choudhari

JR3,Dept of Pharmacology

GMC, Nagpur

1 of 1 File(s)

Img 1.doc

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