Re: Sammy joes update on LDN trial

[Guest guest]

Thanks SammyJo. All of your points are well made. It is exciting! Just to know that there is the posibility that someday LDN will be the first line of defense against this situation is good news!

Marcie (PPMS)

In a message dated 8/28/2004 12:20:53 PM Central Standard Time, redtruck99@... writes:

The concerns you bring up are totally valid, and always an issue with research. My thoughts:

[Guest guest]

The concerns you bring up are totally valid, and always an issue with

research. My thoughts:

1. We are lucky this is being done at a well funded big academic

institution, which is more likely above the reach of NMSS or drug

companies. Everything I have witnessed as this has evolved indicates

pure research interest into a promising med - exactly what we've bee

asking for.

2. Academic researchers are required to address treatment ethics with

every trial, and the patients will have to go through lengthy

informed consent education. Until we see the trial proposal, we

should not try to second guess how this will be handled.

3. Subjects in trials get more medical attention than through regular

treatment, so if the docs see somebody going downhill fast, they

aren't going to leave them w/o help, just to maintain the study.

4. The bottom line: you can use the existance of this planned trial

to score points with docs today - they will be more likely to

prescribe once they hear this is in the works. If we continue the

grass roots effort to spread LDN's acceptance, in the end that could

eclipse the need for double blind studies, and they could jump right

to observational results for those who are using LDN, so nobody has

to do without it.

SammyJo

[Guest guest]

Well said.

----- Original Message -----

From: redtruck99

low dose naltrexone

Sent: Saturday, August 28, 2004 10:45 AM

Subject: [low dose naltrexone] Re: Sammy joes update on LDN trial

The concerns you bring up are totally valid, and always an issue with research. My thoughts:1. We are lucky this is being done at a well funded big academic institution, which is more likely above the reach of NMSS or drug companies. Everything I have witnessed as this has evolved indicates pure research interest into a promising med - exactly what we've bee asking for. 2. Academic researchers are required to address treatment ethics with every trial, and the patients will have to go through lengthy informed consent education. Until we see the trial proposal, we should not try to second guess how this will be handled.3. Subjects in trials get more medical attention than through regular treatment, so if the docs see somebody going downhill fast, they aren't going to leave them w/o help, just to maintain the study. 4. The bottom line: you can use the existance of this planned trial to score points with docs today - they will be more likely to prescribe once they hear this is in the works. If we continue the grass roots effort to spread LDN's acceptance, in the end that could eclipse the need for double blind studies, and they could jump right to observational results for those who are using LDN, so nobody has to do without it. SammyJo