Re: MTHFR (causing weight issues?)

[Guest guest]

Okay .. one more thought/question in regards to the MTHFR defect. The MTHFR defect affects methylation. Sluggish methylation causes allergies, which in turn causes inflammation, etc. Would it make sense to concur that if we have the MTHFR defect that it would also cause our weight issues .. even when we are on optimal doses of Armour (thyroid medication) and optimal iodine and (other) supplements?

Also with this MTHFR defect, wouldn't it make it much more difficult to detox the way we should while on the iodine protocol.. thus maybe causing those weight issues again?

Just wondering .. ~Glo

From: ladybugsandbees <ladybugsandbees@ sbcglobal. net>Subject: Re: MTHFRiodinegroups (DOT) comDate: Friday, October 10, 2008, 8:07 AM

Yes there is a lot I can offer here. This is my new research project. LOL! So let me go through your questions in order.

1. My hubby and I both have the MTHFR defect. I am having a consult with Dr. B today to discuss the specifics of which my hubby has but my suspicion is that it is the C677T form as he has a lab slip to go for blood work to check his homocystine levels. I have the A1298C form. So what if any my children have is up in the air. We too are awaiting the DMG product as it is on backorder but when it comes 3 of the 4 of us will take it. My daughter is not on it because a) she is stubborn and we need to pick our battles and there were no physical issues like behavior / brain fog that we were trying to overcome as were in my son. My mom also has the MTHFR defect and takes the DMG product too.

2. Metagenics Actifolate is the same as the Folinic Acid. For some reason there are different names but both are the 5-Tetra Hyrofolate form (reduced). The difference with the Actifolate and the DMG product is that Dr B has added the DMG, Methyl B12, Choline and Riboflavin - all items that have a specific purpose in "plugging" into the methylation cycle. I have attached the Methylation chart again for everyone's reference. I took Actifolate for a while - given to me by my ND. He did no testing just said that for many people it helped clear brain fog and give them energy. It is the reduced form of the folate so your body does not have to convert it - it is not dangerous to anyone w/o the defect just lets the body not work as hard to "reduce" it. My personal feeling is that Dr B's DMG product is the best option.

Hope that helps.

Steph

MTHFR

Hi,

While I know that this is not under our iodine topic, I think that it is probably relative in that so many of us with our iodine/thyroid issues have this.

I read some of Steph's posts .. and it looks like her whole family (including hubby) is on the DMG for MTHFR. Did I read that right Steph?

I discovered at my last appt. with Dr. B that I too had this deficiency and am anxiously awaiting a new batch of DMG that is custom made for Dr. B's patients.

All within the same two weeks of my blood test results, my dad received a phone call from his dr. at Born Clinic. This dr. told him that particular blood test (testing for MTHFR) was too expensive and he could "tell" by looking at other blood levels that this must be an issue for him. (This is how my 76 yr. old mom explained it to me, anyways. ;-) He put my dad on Metagenics Actifolate. When you read the description of this product, it states that it helps specifically with MTHFR. (I'm pretty sure that's how it read.) His doc is not giving him DMG along with this.

I am thinking that he would probably do much better with having the DMG that has the folinic acid right in in. (Dr. B's custom mix.) What do you think Steph .. or anyone?

Also, considering my situation .. my mother was asking me if she should maybe start supplementing with dad's Actifolate. I told her that I would "ask" someone .. but thought that it probably wouldn't hurt. Didn't know for sure ..?

Any thoughts on any of this?

~Glo

[Guest guest]

Hi Glory:

Just curious, how are your temperatures?

From: ladybugsandbees <ladybugsandbees@ sbcglobal. net>Subject: Re: MTHFRiodinegroups (DOT) comDate: Friday, October 10, 2008, 8:07 AM

Yes there is a lot I can offer here. This is my new research project. LOL! So let me go through your questions in order.

1. My hubby and I both have the MTHFR defect. I am having a consult with Dr. B today to discuss the specifics of which my hubby has but my suspicion is that it is the C677T form as he has a lab slip to go for blood work to check his homocystine levels. I have the A1298C form. So what if any my children have is up in the air. We too are awaiting the DMG product as it is on backorder but when it comes 3 of the 4 of us will take it. My daughter is not on it because a) she is stubborn and we need to pick our battles and there were no physical issues like behavior / brain fog that we were trying to overcome as were in my son. My mom also has the MTHFR defect and takes the DMG product too.

2. Metagenics Actifolate is the same as the Folinic Acid. For some reason there are different names but both are the 5-Tetra Hyrofolate form (reduced). The difference with the Actifolate and the DMG product is that Dr B has added the DMG, Methyl B12, Choline and Riboflavin - all items that have a specific purpose in "plugging" into the methylation cycle. I have attached the Methylation chart again for everyone's reference. I took Actifolate for a while - given to me by my ND. He did no testing just said that for many people it helped clear brain fog and give them energy. It is the reduced form of the folate so your body does not have to convert it - it is not dangerous to anyone w/o the defect just lets the body not work as hard to "reduce" it. My personal feeling is that Dr B's DMG product is the best option.

Hope that helps.

Steph

MTHFR

Hi,

While I know that this is not under our iodine topic, I think that it is probably relative in that so many of us with our iodine/thyroid issues have this.

I read some of Steph's posts .. and it looks like her whole family (including hubby) is on the DMG for MTHFR. Did I read that right Steph?

I discovered at my last appt. with Dr. B that I too had this deficiency and am anxiously awaiting a new batch of DMG that is custom made for Dr. B's patients.

All within the same two weeks of my blood test results, my dad received a phone call from his dr. at Born Clinic. This dr. told him that particular blood test (testing for MTHFR) was too expensive and he could "tell" by looking at other blood levels that this must be an issue for him. (This is how my 76 yr. old mom explained it to me, anyways. ;-) He put my dad on Metagenics Actifolate. When you read the description of this product, it states that it helps specifically with MTHFR. (I'm pretty sure that's how it read.) His doc is not giving him DMG along with this.

I am thinking that he would probably do much better with having the DMG that has the folinic acid right in in. (Dr. B's custom mix.) What do you think Steph .. or anyone?

Also, considering my situation .. my mother was asking me if she should maybe start supplementing with dad's Actifolate. I told her that I would "ask" someone .. but thought that it probably wouldn't hurt. Didn't know for sure ..?

Any thoughts on any of this?

~Glo

[Guest guest]

Hi ,

To be real honest, it's been a long time since I monitored my temperatures. Most recently, I have been running on the "hot" side .. only because (I think) I went off my prog/testosterone cream (2 months ago) and then I ran out of my Sun-flax oil. I actually had "burn" flashes. (I truly felt like I had a bad sunburn from the inside out! )

Because I ran out of my flax, went off my bioidentical hormone cream AND upped my Armour .. the doc thought that all of those things contributed to my "burn" flashes.

My FT3 three weeks ago was at 433 (230-420). If I was feeling good otherwise, Dr. B (I'm thinking) would have allowed me to stay on my full 3 grains of Armour. But because I had only just recently increased by 1/4 grain (that's where another "change" was) he suggesed I back down that 1/4 grain. I am now NOT having any kind of hot flashes or night sweats. I guess I did that all to myself, huh?

Once I get situated, after another two weeks, I will start monitoring my temps again. But ..as I said .. recently I've been running consistently "warm".

Thanks,

~Glo

From: ladybugsandbees <ladybugsandbees@ sbcglobal. net>Subject: Re: MTHFRiodinegroups (DOT) comDate: Friday, October 10, 2008, 8:07 AM

Yes there is a lot I can offer here. This is my new research project. LOL! So let me go through your questions in order.

1. My hubby and I both have the MTHFR defect. I am having a consult with Dr. B today to discuss the specifics of which my hubby has but my suspicion is that it is the C677T form as he has a lab slip to go for blood work to check his homocystine levels. I have the A1298C form. So what if any my children have is up in the air. We too are awaiting the DMG product as it is on backorder but when it comes 3 of the 4 of us will take it. My daughter is not on it because a) she is stubborn and we need to pick our battles and there were no physical issues like behavior / brain fog that we were trying to overcome as were in my son. My mom also has the MTHFR defect and takes the DMG product too.

2. Metagenics Actifolate is the same as the Folinic Acid. For some reason there are different names but both are the 5-Tetra Hyrofolate form (reduced). The difference with the Actifolate and the DMG product is that Dr B has added the DMG, Methyl B12, Choline and Riboflavin - all items that have a specific purpose in "plugging" into the methylation cycle. I have attached the Methylation chart again for everyone's reference. I took Actifolate for a while - given to me by my ND. He did no testing just said that for many people it helped clear brain fog and give them energy. It is the reduced form of the folate so your body does not have to convert it - it is not dangerous to anyone w/o the defect just lets the body not work as hard to "reduce" it. My personal feeling is that Dr B's DMG product is the best option.

Hope that helps.

Steph

MTHFR

Hi,

While I know that this is not under our iodine topic, I think that it is probably relative in that so many of us with our iodine/thyroid issues have this.

I read some of Steph's posts .. and it looks like her whole family (including hubby) is on the DMG for MTHFR. Did I read that right Steph?

I discovered at my last appt. with Dr. B that I too had this deficiency and am anxiously awaiting a new batch of DMG that is custom made for Dr. B's patients.

All within the same two weeks of my blood test results, my dad received a phone call from his dr. at Born Clinic. This dr. told him that particular blood test (testing for MTHFR) was too expensive and he could "tell" by looking at other blood levels that this must be an issue for him. (This is how my 76 yr. old mom explained it to me, anyways. ;-) He put my dad on Metagenics Actifolate. When you read the description of this product, it states that it helps specifically with MTHFR. (I'm pretty sure that's how it read.) His doc is not giving him DMG along with this.

I am thinking that he would probably do much better with having the DMG that has the folinic acid right in in. (Dr. B's custom mix.) What do you think Steph .. or anyone?

Also, considering my situation .. my mother was asking me if she should maybe start supplementing with dad's Actifolate. I told her that I would "ask" someone .. but thought that it probably wouldn't hurt. Didn't know for sure ..?

Any thoughts on any of this?

~Glo

[Guest guest]

Yes you are on the right track with all thoughts. Dr. B gives MSM to assist with the detoxing since it is a sulfur group.

BTW I forgot to mention that the MTHFR is $250 to test through Quest labs - no insurance.

MTHFR

Hi,

While I know that this is not under our iodine topic, I think that it is probably relative in that so many of us with our iodine/thyroid issues have this.

I read some of Steph's posts .. and it looks like her whole family (including hubby) is on the DMG for MTHFR. Did I read that right Steph?

I discovered at my last appt. with Dr. B that I too had this deficiency and am anxiously awaiting a new batch of DMG that is custom made for Dr. B's patients.

All within the same two weeks of my blood test results, my dad received a phone call from his dr. at Born Clinic. This dr. told him that particular blood test (testing for MTHFR) was too expensive and he could "tell" by looking at other blood levels that this must be an issue for him. (This is how my 76 yr. old mom explained it to me, anyways. ;-) He put my dad on Metagenics Actifolate. When you read the description of this product, it states that it helps specifically with MTHFR. (I'm pretty sure that's how it read.) His doc is not giving him DMG along with this.

I am thinking that he would probably do much better with having the DMG that has the folinic acid right in in. (Dr. B's custom mix.) What do you think Steph .. or anyone?

Also, considering my situation .. my mother was asking me if she should maybe start supplementing with dad's Actifolate. I told her that I would "ask" someone .. but thought that it probably wouldn't hurt. Didn't know for sure ..?

Any thoughts on any of this?

~Glo

[Guest guest]

This conversation is very interesting & very scientific & over my head, butgiven that my sister, Mom & I have Hypo & weight gain....What test should we take, what  is the cost,do you have to get it through a doctor,and what is the stuff that is supposed to help people who test positive for this defect, and where can you buy it,and what is the cost?Sorry for all the questions but I have been looking forward to being skinny every year that my beauty fades,and every summer that I think I'll have the weight thing under control,and don't..... well it's pretty depressing, not to mention all of theother wretched symptoms.Thank you,AliOn Oct 10, 2008, at 7:35 AM, ladybugsandbees wrote: Yes you are on the right track with all thoughts.  Dr. B gives MSM to assist with the detoxing since it is a sulfur group.    BTW I forgot to mention that the MTHFR is $250 to test through Quest labs - no insurance.   MTHFR Hi,   While I know that this is not under our iodine topic, I think that it is probably relative in that so many of us with our iodine/thyroid issues have this. I read some of Steph's posts .. and it looks like her whole family (including hubby) is on the DMG for MTHFR.  Did I read that right Steph?    I discovered at my last appt. with Dr. B that I too had this deficiency and am anxiously awaiting a new batch of DMG that is custom made for Dr. B's patients.    All within the same two weeks of my blood test results, my dad received a phone call from his dr. at Born Clinic. This dr. told him that particular blood test (testing for MTHFR) was too expensive and he could "tell" by looking at other blood levels that this must be an issue for him.  (This is how my 76 yr. old mom explained it to me, anyways. ;-)  He put my dad on Metagenics Actifolate.  When you read the description of this product, it states that it helps specifically with MTHFR.  (I'm pretty sure that's how it read.)  His doc is not giving him DMG along with this.    I am thinking that he would probably do much better with having the DMG that has the folinic acid right in in. (Dr. B's custom mix.)  What do you think Steph .. or anyone?   Also, considering my situation .. my mother was asking me if she should maybe start supplementing with dad's Actifolate.  I told her that I would "ask" someone .. but thought that it probably wouldn't hurt.  Didn't know for sure ..?   Any thoughts on any of this? ~Glo       

[Guest guest]

I am not sure that the MTHFR will help you lose weight. I am finding that this is a matter of toxicity. You need to detox, detox, detox. Also those of us with thyroid conditions tend to be gluten sensitive or even celiac. Giving up gluten helped with the weight issue as well.

As for the test. It is just called MTHFR and yes you need a doctor. Quest charges $250. The rest of your questions have been answered in other e-mails that you can look at on the board.

Steph

MTHFR

Hi,

While I know that this is not under our iodine topic, I think that it is probably relative in that so many of us with our iodine/thyroid issues have this.

I read some of Steph's posts .. and it looks like her whole family (including hubby) is on the DMG for MTHFR. Did I read that right Steph?

I discovered at my last appt. with Dr. B that I too had this deficiency and am anxiously awaiting a new batch of DMG that is custom made for Dr. B's patients.

All within the same two weeks of my blood test results, my dad received a phone call from his dr. at Born Clinic. This dr. told him that particular blood test (testing for MTHFR) was too expensive and he could "tell" by looking at other blood levels that this must be an issue for him. (This is how my 76 yr. old mom explained it to me, anyways. ;-) He put my dad on Metagenics Actifolate. When you read the description of this product, it states that it helps specifically with MTHFR. (I'm pretty sure that's how it read.) His doc is not giving him DMG along with this.

I am thinking that he would probably do much better with having the DMG that has the folinic acid right in in. (Dr. B's custom mix.) What do you think Steph .. or anyone?

Also, considering my situation .. my mother was asking me if she should maybe start supplementing with dad's Actifolate. I told her that I would "ask" someone .. but thought that it probably wouldn't hurt. Didn't know for sure ..?

Any thoughts on any of this?

~Glo