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OK...I'll bite. What is PB???

BarbF

In a message dated 8/20/2008 4:43:10 P.M. Eastern Daylight Time, ladybugsandbees@... writes:

I found this chapter in a military guide today on Bromism. I thought some of you might find it interesting.

It's only a deal if it's where you want to go. Find your travel deal here.

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For anyone reading the link Steph gave below:

PGW = Persian Gulf War

PB = pyridostigmine bromine, a nerve agent.

In the section subtitled "Mechanism of Bromism", the author says

"It is assumed that bromide acts by replacing part of the chloride in the body (Blumberg and Nelp, 1966)." Isn't this wrong? I thought it was because bromide was replacing iodide in the body. If they're starting out with the incorrect assumption that the bromide is replacing part of the chloride, seems like many other things could be wrong, such as the treatments.

In the very last paragraph, the article discussed a modern-day woman who had taken a triple bromide elixir for 7 years, prescribed for a post-head-injury seizure condition, who had a high serum bromide level. She was treated with isotonic saline and daily injections of mercaptomerin sodium (Thiomeri). Thiomeri is a mercury containing diuretic. Seems rather barbaric to me, to be injecting a mercury-containing drug to cure bizarre behavior and hallucinations. Gives me the shivers.

Lynn

Bromism

I found this chapter in a military guide today on Bromism. I thought some of you might find it interesting.

http://www.gulflink.osd.mil/library/randrep/pb_paper/mr1018.2.chap10.html

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Just to chime in a little bit here. I was on PB during my twenties

(now 53) for myasthenia gravis. Let me tell you, if you need it, it is

a wonderful drug! I had such horrible unexplained muscle weakness, and

it was progressive. On the other hand, the first remission I had,

although temporary, I accidentally overdosed myself with PB and that's

no fun either! :) Ah, the memories.....

Of course, I am paying the price of that plus Mountain Dew now, and my

firstborn, conceived one month after I went into remission from MG,

may also be paying a price. He is getting a loading test soon. But you

know, you can only do your best with the knowledge and guidance that

you have at the time. :)

Blessings-

Vicki

>

> For anyone reading the link Steph gave below:

> PGW = Persian Gulf War

> PB = pyridostigmine bromine, a nerve agent.

>

> In the section subtitled " Mechanism of Bromism " , the author says

> " It is assumed that bromide acts by replacing part of the chloride

in the body (Blumberg and Nelp, 1966). " Isn't this wrong? I thought

it was because bromide was replacing iodide in the body. If they're

starting out with the incorrect assumption that the bromide is

replacing part of the chloride, seems like many other things could be

wrong, such as the treatments.

>

> In the very last paragraph, the article discussed a modern-day woman

who had taken a triple bromide elixir for 7 years, prescribed for a

post-head-injury seizure condition, who had a high serum bromide

level. She was treated with isotonic saline and daily injections of

mercaptomerin sodium (Thiomeri). Thiomeri is a mercury containing

diuretic. Seems rather barbaric to me, to be injecting a

mercury-containing drug to cure bizarre behavior and hallucinations.

Gives me the shivers.

>

> Lynn

> Bromism

>

>

> I found this chapter in a military guide today on Bromism. I

thought some of you might find it interesting.

>

>

http://www.gulflink.osd.mil/library/randrep/pb_paper/mr1018.2.chap10.html

>

>

>

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pyridostigmine bromine http://www.fda.gov/Cder/drug/infopage/Pyridostigmine_Bromide/default.htm

Re: Bromism

OK...I'll bite. What is PB???

BarbF

In a message dated 8/20/2008 4:43:10 P.M. Eastern Daylight Time, ladybugsandbees@... writes:

I found this chapter in a military guide today on Bromism. I thought some of you might find it interesting.

It's only a deal if it's where you want to go. Find your travel deal here.

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aka " Mestinon "

I will attest to it's short half-life also, as mentioned in the

article about the Gulf War Veterans. I could certainly tell when my

PB/Mestinon was running out and my next dose was due. I was on a four

hour schedule and at 3 hours 45 minutes I always felt weak and knew my

time was almost up! It was a medicine that always had to be taken with

protein so it would be absorbed more slowly. I know, more than you all

wanted to know. :)

Blessings-

Vicki

>

> pyridostigmine bromine

http://www.fda.gov/Cder/drug/infopage/Pyridostigmine_Bromide/default.htm

>

>

> Re: Bromism

>

>

> OK...I'll bite. What is PB???

> BarbF

>

>

> In a message dated 8/20/2008 4:43:10 P.M. Eastern Daylight Time,

ladybugsandbees@... writes:

>

> I found this chapter in a military guide today on Bromism. I

thought some of you might find it interesting.

>

>

>

>

>

>

>

------------------------------------------------------------------------------

> It's only a deal if it's where you want to go. Find your travel

deal here.

>

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Its interesting info though. Thanks for sharing!

Steph

Re: Bromism

>>

>>

>> OK...I'll bite. What is PB???

>> BarbF

>>

>>

>> In a message dated 8/20/2008 4:43:10 P.M. Eastern Daylight Time,

> ladybugsandbees@... writes:

>>

>> I found this chapter in a military guide today on Bromism. I

> thought some of you might find it interesting.

>>

>>

>>

>>

>>

>>

>>

> ------------------------------------------------------------------------------

>> It's only a deal if it's where you want to go. Find your travel

> deal here.

>>

>

>

>

> ------------------------------------

>

>

>

>

>

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