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CLIP PEPTIDE INFLUENCES IMMUNE RESPONSE> Researchers at Roche Basel, in collaboration with immunologists at Harvard > Medical School in Boston, have discovered a naturally occurring peptide* > that could play a significant role in the fight against autoimmune > diseases, according to the September issue of Nature Immunology.>> The CLIP peptide, which stands for class II associated invariant chain > peptide, reduces the production of the immune system cells that trigger > pro-inflammatory immune responses, including autoimmunity. These findings > may lead to new therapeutic strategies for autoimmune diseases.>> In a series of pre-clinical studies, researchers showed that specialized > cells of the immune system activate the natural occurring peptide CLIP on > the cell surface. CLIP appeared to function as a new type of peptide > regulator. More importantly, researchers found that synthetic CLIP > functioned in the same way as naturally occurring CLIP, which indicates > the potential of using synthetic CLIP (or variants thereof) as therapeutic > agents for various autoimmune diseases.>> "The potential pharmacological importance of this discovery comes from the > fact that modulating levels of CLIP may be used to modulate the immune > response itself," said Ira Mellman, Department Head Ludwig Institute of > Cancer Research at Yale University in New Haven.>> *peptide: a compound containing two or more amino acids.>>

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The University of Alberta here in Edmonton is also doing a similar

study and I have added my name...hoping to get in on the study.

Kathy

On 1-Oct-04, at 1:59 PM, Bayuk wrote:

> CLIP PEPTIDE INFLUENCES IMMUNE RESPONSE

> > Researchers at Roche Basel, in collaboration with immunologists at

> Harvard

> > Medical School in Boston, have discovered a naturally occurring

> peptide*

> > that could play a significant role in the fight against autoimmune

> > diseases, according to the September issue of Nature Immunology.

> >

> > The CLIP peptide, which stands for class II associated invariant

> chain

> > peptide, reduces the production of the immune system cells that

> trigger

> > pro-inflammatory immune responses, including autoimmunity. These

> findings

> > may lead to new therapeutic strategies for autoimmune diseases.

> >

> > In a series of pre-clinical studies, researchers showed that

> specialized

> > cells of the immune system activate the natural occurring peptide

> CLIP on

> > the cell surface. CLIP appeared to function as a new type of peptide

> > regulator. More importantly, researchers found that synthetic CLIP

> > functioned in the same way as naturally occurring CLIP, which

> indicates

> > the potential of using synthetic CLIP (or variants thereof) as

> therapeutic

> > agents for various autoimmune diseases.

> >

> > " The potential pharmacological importance of this discovery comes

> from the

> > fact that modulating levels of CLIP may be used to modulate the

> immune

> > response itself, " said Ira Mellman, Department Head Ludwig Institute

> of

> > Cancer Research at Yale University in New Haven.

> >

> > *peptide: a compound containing two or more amino acids.

> >

> >

>

>

>

>

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  • 1 year later...
Guest guest

Hi Bettina,

Welcome to the group. I am certatin that your son has metal toxicity induced

autism and may not be brain damaged, and I highly recommend that you start

thinking about chelation of your child especially while he is young because

the younger the child, the better and faster metal excretion.

This is not to say that he is not benefitting from enzyme. Enzymes are really

wonderful for all people with injured gut with or without special diet.

However, autism (mecury and other metal poisoning) is multi factorial

autoimmune disorder that will improve dramatically and even reverses buy

detoxification.

Best,

Haleh

--- bettinastuetz369 <tinawolf@...> wrote:

> Hi All, I am new to this group

> My name is Bettina, I live in South Africa, I am a mother of three.

> Our youngest son, Sebastian, 4yrs, has brain damage. we recently did

> urine stool and hair tests. sebastian has high levels of mercury lead

> aluminium arsenic so I have decided he may be classified as autistic.

> he has inflammatory bowel disease Sebastian is non verbal. The main

> issues we have always had is cramping after eating, he is on a gfcf

> diet. i recently bought ENZYMES by DEFelice and i think this is

> the best book i have read so far. i have been researching for four

> years.

> just a quick question I have started sebastian on Digest from

> enzymedica , it includes protease at 42000 hut. what is the difference

> between protease to break down protein and peptidase to break down

> peptides. does the protease not break down the protein sufficiently.

>

> i have started at a 1/4 capsule and now after a week give 1/2 at

> mealtimes the recommended dosage for children under three is 1/2

> capsule. do you find children with bad digestion need more or do you

> follow the guidelines.

>

> i am really hoping this will be the start of something good for

> sebastian.

>

> thanks love from sa

> Tina

>

>

>

>

>

>

>

>

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