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Re: The Wide ranges in armour doses?

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Hi Chuck

I agree but why then is it banned in Germany?

Heres the whole page http://en.wikipedia.org/wiki/Titanium_dioxide

and another http://www.ukfoodguide.net/e171.htm

Chris

>

> If it isn't nitrogen, oxygen, or water vapor, it does not belong

in our

> lungs. That doesn't mean it will be a hazard in food, medicine, or

on

> our skin, though.

>

> Chuck

>

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Nature Throid - from www.internationalpharmacy.com

Luv - Sheila

Oh by the way, what is that natural dessicated thyroid brand that istotally hypoallergenic, is it Biothroid?lotsa luvDawnx

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Val,

You asked about:

>

> If Armour is a natural timed release version of T3, then this would rule

> out sublingual administration, right?

That was in response to someone else's posting about the slow absorption of T3

from Armour, which evidently requires digestive juices to break down the

glandular tissue before the T3 can be absorbed. So, if T3 is not absorbed until

the Armour reaches your stomach, you can't very well take it under your tongue,

although that is how some people recommend taking it.

Chuck

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Hi Chuck - I must have missed the previous post - can you point it out to me please. Id very much like to look into this.

Thanks,

Gill

> If Armour is a natural timed release version of T3, then this would rule > out sublingual administration, right?That was in response to someone else's posting about the slow absorption of T3 from Armour, which evidently requires digestive juices to break down the glandular tissue before the T3 can be absorbed. So, if T3 is not absorbed until the Armour reaches your stomach, you can't very well take it under your tongue, although that is how some people recommend taking it.Chuck

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Hi Gill

I think Chuck probably means me when I responded to the BTA statement on Armour saying "...Armour Thyroid does have a higher amount of T3 compared to T4 than the relative amounts of T3 to T4 secreted by the human thyroid gland, however it is well documented that Armour is often more effective and is better tolerated than synthetic preparations of T4, T3 and T4/T3 combination. This is because the T3 in natural thyroid extract is absorbed more slowly than synthetic (purified, unbound) T3."

However, If T3 require digestive juices to break down the glandular tissue before T3 can be absorbed, why doesn't it have a hard coating so it is not dissolved in the acids in the stomach, but passes through the stomach into the small intestine prior to the beginning of dissolution. Armour tablets do not have such a coating, and this is the reason I was given as to why those who swallow their tablets could lose up to 45% of its potency. That made sense to me. Armour can be dissolved under the tongue - I have never done it any other way.

Luv - Sheila

 Hi Chuck - I must have missed the previous post - can you point it out to me please. Id very much like to look into this.Thanks,Gill> If Armour is a natural timed release version of T3, then this would rule > out sublingual administration, right?That was in response to someone else's posting about the slow absorption of T3 from Armour, which evidently requires digestive juices to break down the glandular tissue before the T3 can be absorbed. So, if T3 is not absorbed until the Armour reaches your stomach, you can't very well take it under your tongue, although that is how some people recommend taking it.Chuck

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Thanks Chuck,

I always take my 2grains armour first thing in the morning sub-lingually, and perhaps my 3/4 grain later in the day either-way. I will try swallowing both for a while to see if this affects my energy.

Val

That was in response to someone else's posting about the slow absorption of T3 from Armour, which evidently requires digestive juices to break down the glandular tissue before the T3 can be absorbed. So, if T3 is not absorbed until the Armour reaches your stomach, you can't very well take it under your tongue, although that is how some people recommend taking it.Chuck

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Thanks Sheila, makes sense now!

Gill

 I think Chuck probably means me when I responded to the BTA statement on Armour

..

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Sheila,

You wrote:

>

> However, If T3 require digestive juices to break down the glandular

> tissue before T3 can be absorbed, why doesn't it have a hard coating so

> it is not dissolved in the acids in the stomach, but passes through the

> stomach into the small intestine prior to the beginning of

> dissolution.

Non sequitur. When you swallow thyroxines of any form, most of the

absorption occurs in the intestine. Why would a coating be helpful, let

alone necessary, to make something happen that happens naturally, anyway?

You cited Hertoghe's paper that showed that T3 in Armour was absorbed

more slowly than synthetics. That means it is " protected " by the

structure of the tissue, very common for active ingredients in

glandulars. The only way that 45% is not absorbed is if you violate the

1 hour rule on food. Evidently that also applies to coffee, much as I

hate to acknowledge that. It is really hard to wait that long for the

first cup!

Chuck

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Hi Sheila

No thyroxine has a hard coating.

Chris

>

> Hi Gill

>

> However, If T3 require digestive juices to break down the

glandular tissue before T3 can be absorbed, why doesn't it have a

hard coating so it is not dissolved in the acids in the stomach,

but passes through the stomach into the small intestine prior to the

beginning of dissolution. Armour tablets do not have such a coating,

and this is the reason I was given as to why those who swallow their

tablets could lose up to 45% of its potency. That made sense to me.

Armour can be dissolved under the tongue - I have never done it any

other way.

>

> Luv - Sheila

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HI Val

If you take all your Armour at night when you go to bed, there will be no problem as many of us are finding out Val. Come and join the club, you will not be disappointed.

Thanks Chuck,

I always take my 2grains armour first thing in the morning sub-lingually, and perhaps my 3/4 grain later in the day either-way. I will try swallowing both for a while to see if this affects my energy.

Val

..

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Hi Chuck,

The recalls of Synthroid and/or other thyroid meds have been over the

issue of 'bio-equivalence' ~ one cannot easily swap from one to

another source of these meds without risking an 'unintended revision'

of dose. Hard coating or no, the quality of the coating may be

influential too.

Those who are very sensitive to changes in dose can swing wildly in

terms of their symptoms and energy levels and moods ....seemingly the

classic trigger of bipolar disorder, of which there is less and less

doubt as to it's cause(s).

The DISC1/2 locus being 'fingered' as a familial cause of both

bipolar disorder and psychosis ( the schizo-affective disorder Dx ).

best wishes

Bob

> > However, If T3 require digestive juices to break down the

glandular tissue before T3 can be absorbed,]]

........ Evidently that also applies to coffee, much as I hate to

acknowledge that. It is really hard to wait that long for the first

cup!

> Chuck

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Bob,

You wrote:

>

> The recalls of Synthroid and/or other thyroid meds have been over the

> issue of 'bio-equivalence' ~ ...

That always meant an effective dose as measured by the change in TSH. My

Mom was caught in the " big one " in the 1980s, when the process for

making Synthroid was changed. Without notice, 200 mcg of Synthroid had

the effect of what had been 230 mcg. Patients all around the globe

suddenly became hyperT. Today, all the generics for levothyroxine have a

strictly controlled " equivalent " dose.

A confused modern use of the term (properly bio-identical) is used to

distinguish chemical forms designed to mimic or have a similar effect to

something found in nature. Prednisone, for example, has many of the same

effects as hydrocortisone, but at much lower concentrations.

Many people, even Shomon herself, have made the mistake of thinking

that the synthetic levothyroxine in Synthroid is a different molecule

from what occurs naturally in mammalian thyroid glands. However, that

thyroxine is also a levo isomer, whether people spell it out or not. It

is bio-identical, the exact same molecule, just made in a test tube.

Coatings have been an important issue for maintaining dose equivalence

during storage. In addition to getting formulations to have the correct

effect on TSH right off the manufacturing floor, pharmaceutical

companies test for retained strength during storage. Coating and

bindings have been selected to maximize this retention of potency, but

there is still some loss from all forms, including Armour, Cytomel, and

Synthroid when stored at room temperature. That is why I store my

prescription in a freezer. The loss is especially large if your meds are

exposed to heat.

Chuck

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I asked Forest whether we should store our Armour in the freezer and they said that although they had not tried it, they saw no reason why this could not be done. However, they did warn that any opened containers should not be stored in the freezer but should be used as normal. Only freeze unopened containers.

Luv - Sheila

Coating and bindings have been selected to maximize this retention of potency, but there is still some loss from all forms, including Armour, Cytomel, and Synthroid when stored at room temperature. That is why I store my prescription in a freezer. The loss is especially large if your meds are exposed to heat.Chuck

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Sheila,

You wrote:

> ... Only freeze unopened containers.

Forest's issue is condensation. Armour in particular is degraded by

exposure to moisture. However, if the freezer is frost-free, and the

environment relatively low in humidity, this should not be a problem. I

only open my T4 container long enough to pop one pill out, and then it

is sealed again.

The usual drop in potency is supposed to be pretty minimal with storage

at room temperature, so the freezer strategy only makes sense if you

need to squeeze the last bit of strength out of your prescription. If

your doctor will just up the prescription a little, that is a comparable

solution.

Chuck

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Ah, but then look at the daily temperature of where you live Chuck and the temperature of where we in the UK live *grin*

Luv - Sheila

The usual drop in potency is supposed to be pretty minimal with storage at room temperature, so the freezer strategy only makes sense if you need to squeeze the last bit of strength out of your prescription. If your doctor will just up the prescription a little, that is a comparable solution.Chuck

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