Anyone able to get full article? My brain hurts and don't know how

[Guest guest]

as this is very true and my cognitive function is impaired, is there

any way I can get to read this paper in full?

lotsa luv

Dawnx

Neuropsychiatric aspects of hypothyroidism and treatment reversibility. .

JD, Tremont G.

Department of Psychiatry and Human Behavior, Brown Medical School,

Providence, RI 02903, USA. jdavis3@...

Thyroid hormone has important actions in the adult brain, and it is

well accepted that hypothyroidism is associated with neuropsychiatric

complaints and symptoms. Neuropsychiatric symptoms refer to a spectrum

of emotional and cognitive problems that are directly related to

changes in the brain secondary to multiple factors, including the

direct effects of thyroid disease, as well as hormone deprivation in

brain tissue. Hypothyroidism impacts aspects of cognitive functioning

and mood. More severe hypothyroidism can mimic melancholic de-pression

and dementia. Neuropsychiatric symptoms tend to improve with treatment

and normalization to a euthyroid state, though the pattern is

inconsistent and complete recovery is uncertain. The degree to which

mild hypothyroidism, or subclinical hypothyroidism (SCH), impacts mood

and cognitive functions and whether these symptoms respond to

treatment, remains controversial. Most studies support a relationship

between thyroid state and cognition, particularly slowed information

processing speed, reduced efficiency in executive functions, and poor

learning. Furthermore, hypo-thyroidism is associated with an increased

susceptibility to depression and reductions in health-related quality

of life. Controlled studies suggest that cognitive and mood symptoms

improve with treatment, though the data are equivocal and limited by

diverse methodologies. Functional neuroimaging data provide support

for the mood and cognitive findings and treatment reversibility for

both overt and SCH. These findings are not, however, without

controversy. Recent investigations into the impact of SCH on cognition

and mood, coupled epidemiological studies investigating the normal

spectrum of thyroid stimulating hormone, have fueled significant

debate regarding the appropriate, healthy range for TSH levels. This

has led to concern over whether patients with overt hypothyroidism may

be undertreated and whether SCH patients are truly out of the range of

normal thyroid functioning and should be treated. The following is a

review of the extant literature on the impact of hypothyroidism on

cognition and mood, reversibility of symptoms, and treatment

approaches. The spectrum of thyroid disease is reviewed, but mild, or

subclinical, hypothyroidism is emphasized. The potential role of

autoimmunity in neuropsychiatric symptoms and treatment resistance is

addressed. Limitations of the current literature and future directions

are discussed

http://www.ncbi.nlm.nih.gov/sites/entrez

[Guest guest]

Save as:-

http://www.minervamedica.it/pdf/R07Y2007/R07Y2007N01A0049.pdf

Bob

>> as this is very true and my cognitive function is impaired, is there> any way I can get to read this paper in full?> > lotsa luv> Dawnx> > Neuropsychiatric aspects of hypothyroidism and treatment reversibility. .> JD, Tremont G.> > Department of Psychiatry and Human Behavior, Brown Medical School,> Providence, RI 02903, USA. jdavis3@...> > Thyroid hormone has important actions in the adult brain, and it is> well accepted that hypothyroidism is associated with neuropsychiatric> complaints and symptoms. Neuropsychiatric symptoms refer to a spectrum

[Guest guest]

Hi Dawn,

Don't wish to state the obvious, but you could write a letter as

you do have the full address, but maybe Bob will help as he is the

scientific whiz.

Subject: Anyone able to get full article? My

brain hurts and don't know how

as this is very true and my cognitive function is impaired, is there

any way I can get to read this paper in full?

lotsa luv

Dawnx

Neuropsychiatric aspects of hypothyroidism and treatment reversibility.

JD, Tremont G.

Department of Psychiatry and Human Behavior, Brown Medical School,

Providence, RI 02903, USA. jdavis3@...

------------------------------------

TPA is not medically qualified. Consult with a qualified medical

practitioner before changing medication.

[Guest guest]

You are of course correct , but I forget about snail mail

nowadays with all this computer stuff, silly me oops.

Thanks Bob hon you is a star.

luv Dawnx