Guest guest Posted October 18, 2004 Report Share Posted October 18, 2004 I have what is probably chronic prostatitis & epididymitis. There is a theory both conditions may in some cases be autoimmune diseases. I read one online post from someone who believed that naltrexone helped. So I'd like to try it. Anyone care to help me get some in New York City? [my email is tilyou1@...]. I'm happy to pay, of course. Part of what encourages me to try is the following statement that I found from a skeptic -- who admits that Naltrexone DOES suppress part of the immune system (and immune system suppression, not enhancement, is what I would expect you'd want in an autoimmune disease). - ================== Naltrexone and other mu-antagonists (e.g. naloxone) have been repeatedly shown to promote a Th2 to Th1 shift in the immune system. This can be helpful in certain situations but disastrous in others. For example, naltrexone has been shown to significantly reduce production of TNF-alpha (Tumor Necrosis Factor alpha), which is a good thing in endotoxin-caused shock, but could be bad in certain cancers (but not all). It is far to simplistic to call naltrexone an "immune booster", since it actually suppresses a part of the immune system. This could be a help in MS, but it also may not have any effect at all. There have been no studies (just checked MedLine) looking at MS and naltrexone. As for AIDS, while opiate use appears to facilitate HIV infection (an effect that is reversed by naltrexone), there is no indication that naltrexone (in the absence of opiates) would be helpful. There are two entries on MedLine that suggest that naltrexone could be useful in AIDS - one by Dr. Bihari (a letter) from 1995 and another clinical trial from 1991. Quote Link to comment Share on other sites More sharing options...
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