Guest guest Posted October 20, 2004 Report Share Posted October 20, 2004 Dear No name, If you had done a bit more research, you would have discovered so much more! No, there have been no scientific trials completed at this point in time. One such trial is being done in regards to Crohns Disease and LDN. I believe this is being done in Pennsylvania. Anyone who takes LDN knows that there is only anecdotal proof so far. If one has a progressed form of a 'disease' and none of the 'scientifically proven' drugs have done any good, then, in my case, I have nothing to lose by trying something that , for unknown reasons, has shown promise. Surely you can understand that? Also, the patent ran out on Naltrexone long ago. How much profit is there to be made in a very inexpensive drug? Do you have the same aversion to the statin drugs being prescribed off-label for MS because they have shown to have some chance of helping the condition? No hard proof, just slight proof. Also many anti-epileptic drugs are prescribed off-label because they may help with spasticity. May not either. LDN is not mentioned in the MS Quartely most likely because the ABCR pharmaceuticals may provide much of their funding. No. I'm not one who thinks that there is a big gov't conspiracy. I just don't happen to believe that a cure or significant symptom improvement is as profitable as the disease itself. Money talks and BS walks as the saying goes! Of course one has to wonder how one drug may be able to help so many varied conditions. Maybe the answer is that the causes of the conditions aren't that different, just the manifestations. If you were in a position to benefit from LDN's use you probably would not be so skeptical. Shame on you for trying to put fear or doubt in the minds of people who may be helped by this drug. People will never know if they don't try it. Also, I feel the need to mention again that the NMSS on two occassions never responded to questions I posed to them when I was in the process of modifying my vehicle in order to be able to drive. They aren't as helpful as some might think! Marcie In a message dated 10/20/2004 8:28:11 AM Central Daylight Time, jelinab_mswalk@... writes: I have to question how a psychiatrist who was the head of the New York city mental health department took it on himself to try a drug designed for the treatment of addicts took it on himself to try this drug on a frined of his daughters to treat her MS. I have checked with the National Multiple Sclerosis research institute in Torrey Pines California. They have never heard of any tests studies on LDN in the treatment of MS. I have to wonder why this "miracle" drug has never been tested. I question why it is not recognized or ever mentioned by the Multiple Sclerosis Quarterly review. Doesn't it make you wonder how this drug can claim success in the treatment of so many diseases? Diseases which are totally unrelated in symptoms and disease progression? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 20, 2004 Report Share Posted October 20, 2004 Did not do enough research..see Remedyfind.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 20, 2004 Report Share Posted October 20, 2004 The simple answer is, there is no money in it. Regards, Tom ----- Original Message ----- From: " Jelina Comittino Breakwell " <jelinab_mswalk@...> <low dose naltrexone > Sent: Wednesday, October 20, 2004 9:25 AM Subject: [low dose naltrexone] I did research on LDN > > > I have to question how a psychiatrist who was the head of the New > York city mental health department took it on himself to try a drug > designed for the treatment of addicts took it on himself to try this > drug on a frined of his daughters to treat her MS. I have checked > with the National Multiple Sclerosis research institute in Torrey > Pines California. They have never heard of any tests studies on LDN > in the treatment of MS. I have to wonder why this " miracle " drug has > never been tested. I question why it is not recognized or ever > mentioned by the Multiple Sclerosis Quarterly review. > Doesn't it make you wonder how this drug can claim success in the > treatment of so many diseases? Diseases which are totally unrelated > in symptoms and disease progression? > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 20, 2004 Report Share Posted October 20, 2004 No, I don't wonder that at all, any of it. Many diseases have the same root cause: an immune system failure of one sort or another. Normalizing the immune system has to be beneficial for a whole host of illnesses. And since Naltrexone is so very inexpensive there is no incentive for anyone to fund a clinical trial. Do you really think the NMSS is interested in curing the disease that is the reason for their existence? I don't, and their actions sure don't indicate a real interest in finding a cure for MS. JT ----- Original Message ----- From: Jelina Comittino Breakwell low dose naltrexone Sent: Wednesday, October 20, 2004 6:25 AM Subject: [low dose naltrexone] I did research on LDN I have to question how a psychiatrist who was the head of the New York city mental health department took it on himself to try a drug designed for the treatment of addicts took it on himself to try this drug on a frined of his daughters to treat her MS. I have checked with the National Multiple Sclerosis research institute in Torrey Pines California. They have never heard of any tests studies on LDN in the treatment of MS. I have to wonder why this "miracle" drug has never been tested. I question why it is not recognized or ever mentioned by the Multiple Sclerosis Quarterly review.Doesn't it make you wonder how this drug can claim success in the treatment of so many diseases? Diseases which are totally unrelated in symptoms and disease progression? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 20, 2004 Report Share Posted October 20, 2004 Good questions all. Amazing isn't it? ----- Original Message ----- From: Jelina Comittino Breakwell low dose naltrexone Sent: Wednesday, October 20, 2004 09:25 Subject: [low dose naltrexone] I did research on LDN I have to question how a psychiatrist who was the head of the New York city mental health department took it on himself to try a drug designed for the treatment of addicts took it on himself to try this drug on a frined of his daughters to treat her MS. I have checked with the National Multiple Sclerosis research institute in Torrey Pines California. They have never heard of any tests studies on LDN in the treatment of MS. I have to wonder why this "miracle" drug has never been tested. I question why it is not recognized or ever mentioned by the Multiple Sclerosis Quarterly review.Doesn't it make you wonder how this drug can claim success in the treatment of so many diseases? Diseases which are totally unrelated in symptoms and disease progression? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 20, 2004 Report Share Posted October 20, 2004 You didn't read Dr. Bihari's entire curriculum. His last degree to receive was in psychiatry. He has degrees in neurology, long before his psychiatry degree. Dr. Bihari is also a scientist. B & others explain why no clinical trials. I'm not skeptical anymore at all because LDN has had my 14 straight year Chronic Progressive MS in a dead halt in progression for 1 year and 4 months. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 20, 2004 Report Share Posted October 20, 2004 Perhaps this will help you understand why LDN is not yet routinely prescribed for MS.... == Why isn't LDN routinely prescribed for MS? Many physicians simply have not yet learned about the positive effects of about LDN on MS symptoms. Others will not prescribe it because it has not yet been approved as an MS treatment by the FDA. == Why hasn't LDN been approved by the FDA? Although Naltrexone (in the higher 50mg dosage) was approved by the FDA in 1984, Low Dose Naltrexone (in the 3mg or 4.5mg dosage) has not yet been submitted for FDA approval. LDN cannot be officially approved by the FDA as an MS therapy until it undergoes specific clinical trials required by the FDA. == Why hasn't LDN gone through a clinical trial as an MS therapy? Clinical trials are very expensive; they are usually initiated and funded by pharmaceutical companies, and these companies are not interested in promoting or marketing LDN. == Why aren't pharmaceutical companies interested in promoting LDN as an MS therapy? Naltrexone was developed so long ago, no one holds a patent; this means that generic versions of the drug can be created and sold very inexpensively. LDN can't make anyone any money; no pharmaceutical company is willing to fund an expensive clinical trial for a drug that will make them so little profit. Also, if LDN were certified by the FDA and became a preferred treatment for MS, the pharmaceutical companies who make the expensive ABCR drugs could lose millions of dollars. == Are any clinical trials of LDN scheduled? Responding to the rapidly-growing, patient-driven publicity about the success of LDN, the MS center at University of Texas recently announced plans for a full clinical trial of LDN as an MS therapy. == Are there any other plans to underwrite a clinical study of LDN and MS? In August 2004, the LDN Research Trust was created in the UK. Conceived by a group of MS patients who have been helped by LDN, the Trust's mission is to raise funds for the initiation of clinical trials for LDN. Their website, www.ldnresearchtrust.org, encourages contributions and participation. In conjunction with the Trust, Dr Alasdair Coles, a neurologist and MS specialist from Cambridge University, and Dr Lawrence of Wales, himself an MS patient, are currently working on a proposal for a clinical trial of LDN for the treatment of MS. == Has LDN been reported in any of the major medical journals? Medical journals are not usually interested in reviewing any drug therapy that has not yet had a clinical trial. However, the well- respected, peer-reviewed medical journal " Medical Hypothesis " recently accepted an LDN/MS hypothesis for publication; it will be published in the next few months. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 20, 2004 Report Share Posted October 20, 2004 You didn't do enough - no PhD for you! :-( Jelina Comittino Breakwell wrote: > > I have to question how a psychiatrist who was the head of the New > York city mental health department took it on himself to try a drug > designed for the treatment of addicts took it on himself to try this > drug on a frined of his daughters to treat her MS. I have checked > with the National Multiple Sclerosis research institute in Torrey > Pines California. They have never heard of any tests studies on LDN > in the treatment of MS. I have to wonder why this " miracle " drug has > never been tested. I question why it is not recognized or ever > mentioned by the Multiple Sclerosis Quarterly review. > Doesn't it make you wonder how this drug can claim success in the > treatment of so many diseases? Diseases which are totally unrelated > in symptoms and disease progression? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 20, 2004 Report Share Posted October 20, 2004 As far as I can see the official MS charities have a common agenda. Ignore enquires for patients. I wrote to the UK MS society twice before my wife started LDN without a reply. They then publish misleading information, the UK - just one cranky doctor in Wales doing it. ( I am sure he is not perfect but he has given as a lot of help for free). They also suggest that all current treatments suppress the immune system but that is no reason to not take an immune system booster at the same time. About the same as telling you not to take your brakes off when you drive your car to sell more brake linings. The US MS society suggest it is an internet marketing scam - so who is making money, a doctor in the US writing prescription in the US would have to be mad to take a bribe from a pharmacy for supplying one of the cheapest drugs available, or are the pharmacies being accused of bribing doctors to write scripts for a cheap drugs, presumably to lower their profits. Australia say it is only a few people in Australia. Well it is very widespread world wide and even if the thousands who say it works (I am one of them) are wrong it is affecting the sales of licensed drugs and I would suggest that is the reason for the misinformation. I doubt there is anyone taking it that would not prefer it to have been tested first- but governments do not test drugs and drug companies only test drugs they could make a profit out of, and this is not one they could profit from. That bit is at least right and proper, who would expect a company to set out to deliberately make a loss If separate organisations in different countries have a common agenda someone must be setting it. I wonder who? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2004 Report Share Posted October 21, 2004 how this drug can claim success in the > treatment of so many diseases? Diseases which are totally unrelated > in symptoms and disease progression? the way I understand how LDN works is this: LDN goes into your brain and stops the production of endorphins for 4-6 hours. It's job is done. It leaves the body. the brain sees that their isn't enough endorphins so it starts producing more. this production make more + T cells now depending on the illness there are a varibale numbre of - T Cells. The body make enought + T cells to equal the number of - T cells. This permits the body to heal itself. So in fact LDN doesn't heal it's your body that does all the work and that's why so many illnesses are helped. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2004 Report Share Posted October 21, 2004 Kudos Marcie!!!!-- In low dose naltrexone , marciemjm@a... wrote: > Dear No name, > > If you had done a bit more research, you would have discovered so much more! > No, there have been no scientific trials completed at this point in time. > One such trial is being done in regards to Crohns Disease and LDN. I believe > this is being done in Pennsylvania. Anyone who takes LDN knows that there is > only anecdotal proof so far. If one has a progressed form of a 'disease' and > none of the 'scientifically proven' drugs have done any good, then, in my case, > I have nothing to lose by trying something that , for unknown reasons, has > shown promise. Surely you can understand that? > > Also, the patent ran out on Naltrexone long ago. How much profit is there to > be made in a very inexpensive drug? Do you have the same aversion to the > statin drugs being prescribed off-label for MS because they have shown to have > some chance of helping the condition? No hard proof, just slight proof. Also > many anti-epileptic drugs are prescribed off-label because they may help with > spasticity. May not either. > > LDN is not mentioned in the MS Quartely most likely because the ABCR > pharmaceuticals may provide much of their funding. No. I'm not one who thinks that > there is a big gov't conspiracy. I just don't happen to believe that a cure or > significant symptom improvement is as profitable as the disease itself. > Money talks and BS walks as the saying goes! > > Of course one has to wonder how one drug may be able to help so many varied > conditions. Maybe the answer is that the causes of the conditions aren't that > different, just the manifestations. > > If you were in a position to benefit from LDN's use you probably would not be > so skeptical. Shame on you for trying to put fear or doubt in the minds of > people who may be helped by this drug. People will never know if they don't > try it. > > Also, I feel the need to mention again that the NMSS on two occassions never > responded to questions I posed to them when I was in the process of modifying > my vehicle in order to be able to drive. They aren't as helpful as some might > think! > > Marcie > > > > In a message dated 10/20/2004 8:28:11 AM Central Daylight Time, > jelinab_mswalk@y... writes: > > > > > > I have to question how a psychiatrist who was the head of the New > > York city mental health department took it on himself to try a drug > > designed for the treatment of addicts took it on himself to try this > > drug on a frined of his daughters to treat her MS. I have checked > > with the National Multiple Sclerosis research institute in Torrey > > Pines California. They have never heard of any tests studies on LDN > > in the treatment of MS. I have to wonder why this " miracle " drug has > > never been tested. I question why it is not recognized or ever > > mentioned by the Multiple Sclerosis Quarterly review. > > Doesn't it make you wonder how this drug can claim success in the > > treatment of so many diseases? Diseases which are totally unrelated > > in symptoms and disease progression? > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2004 Report Share Posted October 21, 2004 , you're right about that! I was VERY surprised that the NMSS gave a 825,000 grant to the Cleveland Clinic to further research on stem cells. If I'm excited about any new programs, it stem cells, they're injecting humans right here in the USA. It's shows great promise in the next five years. From: [mailto:jatrac1@...] Sent: Wednesday, October 20, 2004 10:19 AMlow dose naltrexone Subject: Re: [low dose naltrexone] I did research on LDN No, I don't wonder that at all, any of it. Many diseases have the same root cause: an immune system failure of one sort or another. Normalizing the immune system has to be beneficial for a whole host of illnesses. And since Naltrexone is so very inexpensive there is no incentive for anyone to fund a clinical trial. Do you really think the NMSS is interested in curing the disease that is the reason for their existence? I don't, and their actions sure don't indicate a real interest in finding a cure for MS. JT ----- Original Message ----- From: Jelina Comittino Breakwell low dose naltrexone Sent: Wednesday, October 20, 2004 6:25 AM Subject: [low dose naltrexone] I did research on LDN I have to question how a psychiatrist who was the head of the New York city mental health department took it on himself to try a drug designed for the treatment of addicts took it on himself to try this drug on a frined of his daughters to treat her MS. I have checked with the National Multiple Sclerosis research institute in Torrey Pines California. They have never heard of any tests studies on LDN in the treatment of MS. I have to wonder why this "miracle" drug has never been tested. I question why it is not recognized or ever mentioned by the Multiple Sclerosis Quarterly review.Doesn't it make you wonder how this drug can claim success in the treatment of so many diseases? Diseases which are totally unrelated in symptoms and disease progression? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2004 Report Share Posted October 21, 2004 -------Original Message------- From: Reg Kreil Date: 10/20/04 10:52:25 low dose naltrexone Subject: Re: [low dose naltrexone] I did research on LDN You brought up a very good point when you asked " diseases which are totally unrelated in symptoms and disease progression" Well I believe, like you ,that these are unrelated exept for the fact that they are in our body. I have learned one thing over and over again on these sites and that is the LDN doesn't do any healing or repairing.It just isn't built that way. however it does allow our bodys to repair themselves by slowing down the damage that is constantly being done wether it is from M.S. Aids Lou Gehrigs or what have you.This slowing down of damage is by telling our body to create more helper "T" cells by giving it the impression we are lacking these.These cells assist in disease control and are called the good guys. Our bodys constantly rebuild and repair all day long and of course this is with the materials that we give it. I like to think of these "helper T cells as the cavalry, Sometimes they are still being out numbered by our habits. I eat well and sometimes wrongly(like with too many carbs especially white sugar) and pay for it. We have all seen this, ie a hangover ,indigestion, so maybe we should learn from this and do the best bet diet first.Don't drink alcohol or smoke or eat greasy burgers or fries etc. Well I would like to live like thousands of others not worrying about what I put in my mouth (diet)or drink,but that just isn't going to be the case. For me it was easyier to use a pill so I started LDN. Maybe I have a simplistic idea when it comes to how LDN works but it is my idea, if you don't agree I wouldn't be offended if you try to clear it up. Reg. -------Original Message------- From: low dose naltrexone Date: 10/20/04 07:45:59 low dose naltrexone Subject: Re: [low dose naltrexone] I did research on LDN The simple answer is, there is no money in it.Regards,Tom----- Original Message ----- From: "Jelina Comittino Breakwell" <jelinab_mswalk@...><low dose naltrexone >Sent: Wednesday, October 20, 2004 9:25 AMSubject: [low dose naltrexone] I did research on LDN> > > I have to question how a psychiatrist who was the head of the New > York city mental health department took it on himself to try a drug > designed for the treatment of addicts took it on himself to try this > drug on a frined of his daughters to treat her MS. I have checked > with the National Multiple Sclerosis research institute in Torrey > Pines California. They have never heard of any tests studies on LDN > in the treatment of MS. I have to wonder why this "miracle" drug has > never been tested. I question why it is not recognized or ever > mentioned by the Multiple Sclerosis Quarterly review.> Doesn't it make you wonder how this drug can claim success in the > treatment of so many diseases? Diseases which are totally unrelated > in symptoms and disease progression?> > > > > > > > Quote Link to comment Share on other sites More sharing options...
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