Guest guest Posted December 13, 2008 Report Share Posted December 13, 2008 HI Lizzie So sorry to hear you are suffering so much but your 24 hour adrenal salivary profile definitely is showing a problem and this could be the cause of your symptoms. Your cortisol level should be at its highest first thing in the morning, which it is, so that's OK. However, your midday results suddenly drops right outside the bottom of the range (should be in the middle of the range) and 4.00p.m. results shows it to be right at the bottom of the range (it should be lower but around 8/9) and at midnight, cortisol level should be right at the bottom of the range so you can sleep and yours is at the top. On the other hand, your DHEA when waking should be at the very bottom of the range and yours is way outside the top and again, like your cortisol, it suddenly drops outside the bottom of the range, then the next test it starts to creep up (which it should at this time) and at midnight, it is over the range. Your DHEA should be at its highest point at midnight because this is when you make DHEA. As low adrenal reserve is not recognised in the NHS you will either have to see a private specialist (or Dr Peatfield/Dr Skinner) or read all about this and how to treat it yourself by going to the FILES on this Forum and reading everything about adrenals, and also read the information that is on our website www.tpa-uk.org.uk . Click on 'Hypothyroidism' and then click on 'Associated Conditions' and on the page that opens, click on 'Adrenals'. Anything you do not understand, just shout and we will try to answer any questions. Your thyroid function test results look OK, but as we are very aware, these tests do not show the full picture and you should have had your Free T3 tested to see whether you are converting the mainly inactive hormone T4 into the active hormone T3. You also should be tested to see whether you have antibodies to your thyroid. The NHS synacthen test would make a dead donkey kick after it has been injected with synacthen. This only tests to see if you have 's disease and does not show whether you have any form of low adrenal reserve or not. Luv - Sheila 8am 12midday 4pm 12midnight salivary 24.2 (12-33) 8.4 (10-28) 7.0 (6.11.8) 5.2 (1-5) cortisol salivary 26.2 (9-24.3) 5.9 (6-10.9) 6.1 (4.5-8) 6.5(2.3-5) DHEA age range female 25-34 I'm 33 years old my syncathen result was 815 ((275-690) TSH 1.15 (0.27 - 4.2) Free T4 13.6 (11 - 22) many thanks lizzie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2008 Report Share Posted December 14, 2008 > I'm surprised at your age the GP isn't taking the amenorrhoea more seriously. Have you had any tests related to this? Miriam > my major symptoms are > chronic exhaustion, dizziness, disturbed sleep, muscle fatigue/weakness, emotional disturbance (ie crying!), amenohrrea, > flu like aches, trembling, nausea, diffuculty focusing/concentrating > > age range female 25-34 I'm 33 years old Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2008 Report Share Posted December 14, 2008 dear shiela, thank you so much for your swift and detailed response. it's very reassuring to hear that it's not all in my head. i am reading up and will hopefully take the freeT3 and thyroid anitbodies tests soon. also i have wonderful support and encouragement from my friend sue and have just started nutri-adrenal extra, 1/2 tablet at 8.30am and 1/2 at 12.30 and will see what that does. many thanks for your support lizzie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2008 Report Share Posted December 14, 2008 miriam, thanks for your post. the endocrinolgist picked up on the amenhorrea after a blood test returned low oestrogen levels (oestradiol <200 no range given). she prescribed a contraceptive pill, microgynon which i have held off taking as i haven't had good experince with the pill in the past (weight gain and mood swings). i am hoping that if my adrenals heal my oestrogen production will sort itself out. do you think the pill would help or am i right to trust my instincts? many thanks lizzie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2008 Report Share Posted December 15, 2008 thanks shiela, i will try this lizzie 2 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2008 Report Share Posted December 15, 2008 I can't say, sorry, though as a principle I think it is good to avoid using a sledgehammer to crack a nut. Also the use of synthetic hormones is problematical for two reasons. If they substitute for the natural hormone they don't necessarily work in all the follow-on reactions that a natural one would. Or they may block the uptake of natural hormone and create a deficiency. I think you are right to first try sorting out the other hormones and see if there are knock-on benefits. Miriam > the endocrinolgist picked up on the amenhorrea after a blood test > returned low oestrogen levels (oestradiol <200 no range given). she > prescribed a contraceptive pill, microgynon which i have held off > taking as i haven't had good experince with the pill in the past > (weight gain and mood swings). i am hoping that if my adrenals heal my oestrogen production will sort itself out. do you think the pill would help or am i right to trust my instincts? Quote Link to comment Share on other sites More sharing options...
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