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MsP, you may or may not experience increased muscle stiffness. Some of

us had terrible stiffness on 4.5 mg, but it dissipated on 3. So you

might want to begin with 3 mg and see how it goes if you're already very

stiff. About 25% of Dr. Bihari's patients--of which I'm one--could not

tolerate 4.5, so for them he believes that 3 is the correct dosage.

Under 3 mg, however, he does not believe LDN has an effect. And please

remember that the main reason to take LDN is to prevent further disease

progression. Relief of symptoms doesn't happen for everyone.

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  • 2 weeks later...

Delores, I have been on LDN for 35 days. The first two weeks I had difficulty sleeping, muscle stiffness, very vivid dreams. Now the stiffness has subsided, sleeping is fine.

thinking is clearer, walking improves daily, I have had bladder control from day one of LDN, I am not sure how long I will continue to improve. I will be happy with whatever.

My progression has been a 12 year downhill ride. Steroids helped stop the downhill progression but only put things into a remission state for a short time and symptoms returned worse. Have a wonderful thanksgiving. LDN is giving me hope. ( I hope it will help you also) Best wishes to all! Joanne

-----Original Message-----From: delores crosby [mailto:decrosby@...]Sent: Thursday, November 25, 2004 9:55 AMlow dose naltrexone Subject: RE: [low dose naltrexone] Stiffness

I AM NOT SURE BUT I CAN SAY , AFTER 1 MONTH OF LDN , THAT INITIALLY THE STIFFNESS WAS WORSE BUT IS BEGINNING TO LESSON A LITTLE. IT HAS ALMOST STOPPED THE TIMES OF MUSCLE BECOMING STIFF AND HOLDING FOR A FEW SECONDS (DON'T KNOW IF ANYONE ELSE HAS THIS)

DeLores

decrosby@...

-----Original Message-----From: saranyasaranye [mailto:saranyasaranye@...] Sent: Thursday, November 25, 2004 9:48 AMlow dose naltrexone Subject: [low dose naltrexone] StiffnessWhat is it that causes increased stiffness with LDN? I already had plenty of that before starting. I thought LDN was supposed to help with spasticity. Let's hope we all enjoy the day and eat wisely. Saranya

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Hi Saranya,

I think that everyone is different with MS. The LDn did help me quite a bit with stiffness and spacticity. I am on 4.5mg--maybe that has something to do with it. I have been on LDN for over a year now. Maybe you need to give it time. good Luck

Marie

[low dose naltrexone] Stiffness

What is it that causes increased stiffness with LDN? I already had plenty of that before starting. I thought LDN was supposed to help with spasticity. Let's hope we all enjoy the day and eat wisely. Saranya

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You know I think you may be on to something. Good Question? Maybe it is how LDN workes? Joanne

-----Original Message-----From: usaispy@... [mailto:usaispy@...]Sent: Saturday, November 27, 2004 11:18 AMlow dose naltrexone Subject: Re: [low dose naltrexone] Re: StiffnessHate to be a wet blanket, but could this extra stiffness be what is making you walk better? (not so wobbley)

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