Guest guest Posted November 24, 2008 Report Share Posted November 24, 2008 Oh the memories, the painful painful memories. Scary thing is that it all starts again sometimes when the hc wears off, wonder why? Maybe it is learned now after all these years :(/ ''If let untreated, Myxedema Madness can quickly devolve into a deadly serious condition. Minor anxieties may give way to major psychoses, delusions, hallucinations and paranoia. An otherwise affable person may snap at the slightest annoyance, exhibiting a degree of rage previously unseen. The patient may be diagnosed as schizophrenic, psychotic or manic-depressive. The risk of misdiagnosis is increased because hypothyroidism inordinately impacts women - particularly women over the age of forty. As a result, the emotional difficulties are often attributed to the " natural " process of aging, possibly due to the empty-nest syndrome, the onset of menopause or other adjustments and changes in life. The elderly, especially those already living in a group home setting, face a doubly difficult task in receiving both the proper diagnosis and treatment for this condition. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 24, 2008 Report Share Posted November 24, 2008 Hi Dawn, I'm beginning to believe that Prof Lightman and his group at Bristol University have got this problem cracked (almost). They're saying that it seems all/or most of the psychiatric symptoms can be resolved if the HPA axis is treated properly..... see my notes on the research side of the forum. They (Dr Spiga et al) are looking at agonists (with Organon) for the Glucocorticoid and the Mineralocorticoid receptors in the brain.... and then this evening, I've been reading up on the reaction of the gut to melatonin (puts out bicarbonate when stimulated by melatonin) and the enterochromaffin cells in the GI tract release melatonin under alpha1-adrenergic stimulation (agonist ~ phenylephrine). I've got more reading to do about the melatonin reactions but it's getting highly interesting. If Myxodema Madness is indeed causing far more psychiatric symptoms than has been realised previously, the drug industry is in for a rude awakening. Helicobacter pylori can both increase and also decrease the amount of melatonin produced in the GI tract, according to whether or not it is symptomatic. I've also seen the research data illustrating that at least one anchorage for Candida Albicans is alkaline sensitive.....so is melatonin part of the cure for Candidiasis??? and will alpha1-adrenergic stimulation help? Bicarbonate and melatonin seem to work in harmony....so one would expect to be able to sleep much better, if both of those factors are properly sorted out. One can also imagine that a better sleep profile will also reduce the constant anxiety felt by many sleep disturbed individuals. Good sleepy wishes Bob > Oh the memories, the painful painful memories. Scary thing is that it all starts again sometimes when the hc wears off, wonder why? Maybe it is learned now after all these years :(/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 25, 2008 Report Share Posted November 25, 2008 Awesome research Maybe they are getting somewhere, I seriously hope so, so many people suffering from what you cannot drop a painkiller for You cannot get away from your torturous brain. God help them make this discovery, and God help them please to get it to the people who are suffering. Thanks for the research Bob luv Dawnx Quote Link to comment Share on other sites More sharing options...
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