melatonin and betablockers

[Guest guest]

I have just been reading that Atenolol (the betablocker I have been

taking for 18 months until last

week), it totally wipes out melatonin levels in a very short timespan.

So this could explain a great deal.

The Atenolol would have put my melatonin levels through the floor

which would have allowed the oestrogen to run wild perhaps.

It would also explain why I did not have high oestrogen when tested

two or three years ago and do now (melatonin can suppress oestrogen)

as this was before I started on the betablockers. Interestingly, the

progesterone remains the same (high)in both tests.

And it could also explain why the melatonin did not work for me for

sleep purposes. My levels were probably so very low that the amount

of melatonin I was taking was not impacting on levels sufficiently to

raise them to the point where sleep would be induced.

Mo

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1427710

Administration of atenolol almost totally abolished

the normal night-time rise in plasma melatonin

(Figure 1). Indeed, in three of the subjects the plasma

melatonin concentration was below the detection

limit of the assay.