Fw: Re: high anti tpo and high thyroglobulin / High Seaweed intake hypoT

[Guest guest]

There is a problem with this research. These children tested where tested

positive for congenital hypothyroidism. That is a completely different

animal than normal children w/o this defect. They did not test mothers who

took in high amounts of iodine and did not have a child with this defect.

You can't draw a conclusion on the toxicity of iodine when there is a

pre-disposition to thyroid conditions. Where are the normal children being

evaluated?

Fw: Re: high anti tpo and high thyroglobulin

>

>

> >

> > can any one comment?

> > Gracia

> >

> >> >

> >> Transient Hypothyroidism or Persistent Hyperthyrotropinemia in Neonates

> >> Born to Mothers with Excessive Iodine Intake

> >>

> >> Soroku Nishiyama, Tomohiro Mikeda, Toshihisa Okada, Kimitoshi Nakamura,

> >> Tomio Kotani, Akira Hishinuma. Thyroid. December 1, 2004, 14(12):

> >> 1077-1083.

> >>

> >> Perinatal exposure to excess iodine can lead to transient

> >> hypothyroidism

> >> in the newborn. In Japan, large quantities of iodine-rich seaweed such

> >> as kombu (Laminaria japonica) are consumed. However, effects of iodine

> >> from food consumed during the perinatal period are unknown. The

> >> concentration of iodine in serum, urine, and breast milk in addition to

> >> thyrotropin (TSH), free thyroxine (FT4), and thyroglobulin was measured

> >> in 34 infants who were positive at congenital hypothyroidism screening.

> >> Based on the concentration of iodine in the urine, 15 infants were

> >> diagnosed with hyperthyrotropinemia caused by the excess ingestion of

> >> iodine by their mothers during their pregnancy. According to serum

> >> iodine concentrations, these infants were classified into group A (over

> >> 17 µg/dL) and group B (under 17 µg/dL) of serum iodine. During their

> >> pregnancies these mothers consumed kombu, other seaweeds, and instant

> >> kombu soups containing a high level of iodine. It was calculated that

> >> the mothers of group A infants ingested approximately 2300-3200 µg of

> >> iodine, and the mothers of group B infants approximately 820-1400 µg of

> >> iodine per day during their pregnancies. Twelve of 15 infants have

> >> required levo-thyroxine (LT4) because hypothyroxinemia or persistent

> >> hyperthyrotropinemia was present. In addition, consumption of iodine by

> >> the postnatal child and susceptibility to the inhibitory effect of

> >> iodine may contribute in part to the persistent hyperthyrotropinemia.

> >> We

> >> propose that hyperthyrotropinemia related to excessive iodine ingestion

> >> by the mother during pregnancy in some cases may not be transient.

> >>

> >> Complete paper:

> >> http://www.liebertonline.com/doi/abs/10.1089%2Fthy.2004.14.1077

> >>

> >> Chuck

> >>

> >> ------------------------------------

> >>

> >>

[Guest guest]

,

Congenital, as used in this case, just means that the babies were born

hypothyroid, not

that they had some genetic abnormality or defect. I think it raises some

concerns worth

looking at.

> >

> > It makes me wonder if their seaweed products are filled with toxic halides

> > and arsenic like ours are. If that is the case then it would explain the

> > hypoT more than high iodine levels. I don't know toxicology issues in

> > Japan. Anyone else?

> >

> >

> >

> >

> > Fw: Re: high anti tpo and high thyroglobulin

> >

> >

> > >

> > > can any one comment?

> > > Gracia

> > >

> > >> >

> > >> Transient Hypothyroidism or Persistent Hyperthyrotropinemia in Neonates

> > >> Born to Mothers with Excessive Iodine Intake

> > >>

> > >> Soroku Nishiyama, Tomohiro Mikeda, Toshihisa Okada, Kimitoshi Nakamura,

> > >> Tomio Kotani, Akira Hishinuma. Thyroid. December 1, 2004, 14(12):

> > >> 1077-1083.

> > >>

> > >> Perinatal exposure to excess iodine can lead to transient

> > >> hypothyroidism

> > >> in the newborn. In Japan, large quantities of iodine-rich seaweed such

> > >> as kombu (Laminaria japonica) are consumed. However, effects of iodine

> > >> from food consumed during the perinatal period are unknown. The

> > >> concentration of iodine in serum, urine, and breast milk in addition to

> > >> thyrotropin (TSH), free thyroxine (FT4), and thyroglobulin was measured

> > >> in 34 infants who were positive at congenital hypothyroidism screening.

> > >> Based on the concentration of iodine in the urine, 15 infants were

> > >> diagnosed with hyperthyrotropinemia caused by the excess ingestion of

> > >> iodine by their mothers during their pregnancy. According to serum

> > >> iodine concentrations, these infants were classified into group A (over

> > >> 17 µg/dL) and group B (under 17 µg/dL) of serum iodine. During their

> > >> pregnancies these mothers consumed kombu, other seaweeds, and instant

> > >> kombu soups containing a high level of iodine. It was calculated that

> > >> the mothers of group A infants ingested approximately 2300-3200 µg of

> > >> iodine, and the mothers of group B infants approximately 820-1400 µg of

> > >> iodine per day during their pregnancies. Twelve of 15 infants have

> > >> required levo-thyroxine (LT4) because hypothyroxinemia or persistent

> > >> hyperthyrotropinemia was present. In addition, consumption of iodine by

> > >> the postnatal child and susceptibility to the inhibitory effect of

> > >> iodine may contribute in part to the persistent hyperthyrotropinemia.

> > >> We

> > >> propose that hyperthyrotropinemia related to excessive iodine ingestion

> > >> by the mother during pregnancy in some cases may not be transient.

> > >>

> > >> Complete paper:

> > >> http://www.liebertonline.com/doi/abs/10.1089%2Fthy.2004.14.1077

> > >>

> > >> Chuck

> > >>

> > >> ------------------------------------

> > >>

> > >>