Guest guest Posted September 10, 1999 Report Share Posted September 10, 1999 Roseola is caused by Herpes Virus 6 (see journal abstract below - published this year). - Cory Human herpesvirus 6. Dockrell DH, TF, Paya CV Mayo Clin Proc 1999 Feb 74:2 163-70 Abstract Human herpesvirus (HHV) 6 is a beta-herpes, DNA virus. This virus shows closest homology with cytomegalovirus and HHV-7. Infection usually occurs in infants 6 to 24 months of age, and primary infection may result in roseola. HHV-6 infection in infants is the commonest cause of fever-induced seizures. Infection in adults is seen primarily in immunocompromised hosts with solid organ transplants or in those with human immunodeficiency virus infection. The virus is capable of pronounced interaction in vitro with cytomegalovirus and human immunodeficiency virus and induces immunosuppression and apoptosis. The importance of these interactions in vivo necessitates further investigation. HHV-6 infection may contribute to the pathogenesis of multiple sclerosis. HHV-6 may be diagnosed by viral culture, serology, or polymerase chain reaction. Author Address Division of Infectious Diseases and Internal Medicine, Mayo Clinic Rochester, Minnesota 55905, USA. Quote Link to comment Share on other sites More sharing options...
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