Samter's can sometimes have a cardiovascular impact

[Guest guest]

Proc (Bayl Univ Med Cent). 2011 Apr;24(2):107-9.The Kounis-Zavras syndrome with the Samter-Beer triad.Schwartz BG, Daulat S, Kuiper J.SourceDivision of Cardiology (Schwartz, Kuiper) and the Division of Allergy and Immunology (Daulat), Department of Internal Medicine, Baylor University Medical Center at Dallas.AbstractWe present a case of Kounis-Zavras syndrome in the setting of aspirin-induced asthma, or the Samter-Beer triad of asthma, nasal polyps, and aspirin allergy. The Kounis-Zavras syndrome, also known as Kounis syndrome, leads to angina pectoris or acute coronary syndrome secondary to coronary vasospasm in response to an allergic stimulus, leading to mast-cell degranulation of vasospastic mediators. The vasospasm can result in myocardial infarction, as it did in our patient.