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Cushings Disease

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Cushing's syndrome - 11/3/2007From http://www.wrongdiagnosis.com/sym/cushing_like_symptoms.htm

Cushing's syndrome is a disorder of the adrenal glands leading to excess cortisol secretion. This means that there is too much cortisol hormone in the blood. It can be caused by an adrenal gland failure, or it can result from a pituitary tumor or other tumor that secretes ACTH which in turn stimulates the adrenal glands to over-produce cortisol.

Organ: Adrenal glands

Article Excerpts about Adrenal glands

Cortisol is normally produced by the adrenal glands, located just above the kidneys. It belongs to a class of hormones called glucocorticoids, which affect almost every organ and tissue in the body. Scientists think that cortisol has possibly hundreds of effects in the body. Cortisol's most important job is to help the body respond to stress. Among its other vital tasks, cortisol:

helps maintain blood pressure and cardiovascular function;

helps slow the immune system's inflammatory response;

helps balance the effects of insulin in breaking down sugar for energy; and

helps regulate the metabolism of proteins, carbohydrates, and fats.

Because cortisol is so vital to health, the amount of cortisol produced by the adrenals is precisely balanced. Like many other hormones, cortisol is regulated by the brain's hypothalamus and the pituitary gland, a bean-sized organ at the base of the brain. (Source: excerpt from 's Disease: NIDDK)

▲TopIntroduction: Adrenal insufficiency

Adrenal insufficiency is a failure by the adrenal gland to output enough hormones. Severe or chronic cases, see 's disease, which is a common cause of adrenal failure. Adrenal gland failure may cause an ian crisis.

▲TopSymptoms of Adrenal insufficiency

Fatigue

Weakness

Anorexia

Nausea

Vomiting

Weight loss

Abdominal pain

Cutaneous pigmentation

Mucosal pigmentation

Hypotension

Hypoglycaemia

Note that Adrenal insufficiency symptoms usually refers to various symptoms known to a patient, but the phrase Adrenal insufficiency signs may refer to those signs only noticable by a doctor.

More ways to research these symptoms: To research other symptoms use the symptom center, or to research causes of more than one symptom in combination, try our multi-symptom search

▲TopIntroduction: Pituitary Cancer

Most pituitary tumors are benign. However, because the pituitary is an important hormonal gland, this does not mean they are harmless. Even a benign pituitary tumor can have various severe hormonal affects on the body, and cause various secondary diseases such as Cushing's disease or Acromegaly.

▲TopSymptoms of Pituitary Cancer

Headaches

Vision problems

Visual disturbances

Nausea

Vomiting

Symptoms of various secondary hormonal problems including:

Female infertility

Loss of menstrual periods

Abnormal growth

High blood pressure

Heat intolerance

Cold intolerance

Skin changes

Body changes

Galactorrhea

Note that Pituitary Cancer symptoms usually refers to various symptoms known to a patient, but the phrase Pituitary Cancer signs may refer to those signs only noticable by a doctor.

More ways to research these symptoms: To research other symptoms use the symptom center, or to research causes of more than one symptom in combination, try our multi-symptom search.

▲TopDiagnostic Tests for Cushing's syndrome

Physical examination

Cortisol urine test

24-Hour Urinary Free Cortisol Level

Dexamethasone Suppression Test

CRH Stimulation Test

See full list of 15 diagnostic tests for Cushing's syndrome

▲TopWrongly Diagnosed with Cushing's syndrome?

Misdiagnosis of Cushing's syndrome

Underlying causes of Cushing's syndrome (possibly wrongly diagnosed)

▲TopCauses of Cushing's syndrome

Pituitary tumors

Pituitary adenomas (type of Adenoma) - usually benign ACTH-producing tumors of the pituitary gland; most common in women

ACTH-producing pituitary tumor

Lung tumors - more common in men

Small cell lung cancer

Thymoma

Pancreatic islet cell tumor

Thyroid medullary carcinoma

Adrenocortical carcinomas

Adrenal gland tumor

Adrenal adenomas - benign adrenal tumor

Familial Cushing's Syndrome

Multiple Endocrine Neoplasia Type I

Primary Pigmented Micronodular Adrenal Disease

Carney's complex

McCune-Albright syndrome

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