Sutent side effects.

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Sutent Side Effects:

Important things to remember about the side effects of Sutent:

You will not get all of the side effects mentioned below. Side effects are often predictable in terms of their onset, duration, and severity. Side effects are almost always reversible and will go away after therapy is complete. Side effects are quite manageable. There are many options to minimize or prevent them.

The following side effects are common (occurring in greater than 30%) for patients taking Sutent:

Fatigue Diarrhea Nausea and vomiting Heartburn Taste changes Hypertension (high blood pressure) Low blood counts. Your white and red blood cells and platelets may temporarily decrease. This can put you at increased risk for infection, anemia and/or bleeding. Skin discoloration (possibly due to the drug color - yellow)

The following side effects are less common (occurring in 29-10%) for patients receiving Sutent:

Poor Appetite Headache Increased liver enzymes Weakness Constipation Abdominal pain Bleeding Fever Dry skin Swelling of ankles and feet Dizziness Increased amylase and lipase levels Shortness of breath Generalized aches and pains

Rash Flatulence Hand –foot syndrome (Palmar-plantar erythrodysesthesia or PPE) –skin rash, swelling, redness, pain and/or peeling of the skin on the palms of hands and soles of feet. Dehydration Low potassium levels Increased bilirubin levels Hair color changes Cough Hair loss

Rare (2-3%) but serious side effects may include problems with blood clots. Blood clots can lead to pulmonary embolus or stroke – potentially life-threatening conditions.

This list includes common and less common side effects for those taking Sutent. Side effects that are very rare -- occurring in less than about 10 percent of patients -- are not listed here. But you should always inform your health care provider if you experience any unusual symptoms.

When To Contact Your Doctor or Health Care Provider:

Contact your health care provider immediately, day or night, if you should experience any of the following symptoms:

Fever of 100.5º F (38º C) or higher, chills (possible signs of infection)

The following symptoms require medical attention, but are not an emergency. Contact your health care provider within 24 hours of noticing any of the following:

Nausea (interferes with ability to eat and unrelieved with prescribed medication). Vomiting (vomiting more than 4-5 times in a 24 hour period). Diarrhea (4-6 episodes in a 24-hour period). Unable to eat or drink for 24 hours or have signs of dehydration: tiredness, thirst, dry mouth, dark and decreased amount of urine, or dizziness. Unusual bleeding or bruising Black or tarry stools, or blood in your stools. Blood in the urine. Pain or burning with urination. Extreme fatigue (unable to carry on self-care activities). Mouth sores (painful redness, swelling or ulcers). Swelling, redness and/or pain in one leg or arm and not the other (may be signs and symptoms of blood clot)

Always inform your health care provider if you experience any unusual symptoms.