AW: Re: Cant get rid of infection

[Guest guest]

Hi Joan,I had during the last few infections success with 15G bactroban ointment, by adding a bit into the nasal rinse once a day and some small amount directly into the nose twice a day. Took me each time about a week to clear things and to stop any yellow discharge. The bactronban ointment I'm using is normally for wounds (external use) and burns a bit in the nose - it is not intended for the nose/ internal use - because of this it might have some health risks applying it this way and you might want to get professional advice before trying something like this. Just thought I mention it since you asked.ThanksNilsVon: joan harvey <thomyris7@...>An: samters Gesendet: Montag, den 1. August 2011, 12:26:34 UhrBetreff: Re: Re: Cant get rid of infection

This is interesting. I’ve had an H.flu infection for months, have been on 4 different antibiotics and nothing has worked. They’re supposed to be doing a test to find an antibiotic it isn’t resistant to, but so far the lab has screwed up and done the wrong test, so I’m still waiting. Has anyone had luck with antibiotics directly in the nose?On Jul 31, 2011, at 6:20 PM, wrote:

Don't know about MRSA, but I did have pseudomonas which is also extremely tenacious, and I went on IV therapy for two weeks with Ceftazidime. It seemed to do the trick. Once they put the IV in my arm, a nurse came by to show me how to give myself the meds twice a day - not too bad. Oral antibiotics frequently don't work on chronic bacteria and biofilm. This last therapy seemed to work (knock on wood) and I just had desens so hopefully I am in the clear. Ask about IV therapy.

- In samters , "damianodavid" <damianodavid@...> wrote:

>

> Have you heard of Xylitol?

> I found a study on xylitol an staph and the full text is available pubmed. Their are xylitol nasal sprays available.

>

> Web link xylitol nasal spray:

>

> http://www.xlear.com/nasal-spray.aspx

>

> From Wikipedia:

>

> Xylitol (play /?za?l?t?l/; Greek: ?????, xyl[on], "wood" + suffix -itol, used to denote sugar alcohols) is a sugar alcohol sweetener used as a naturally occurring sugar substitute. It is found in the fibers of many fruits and vegetables, and can be extracted from various berries, oats, and mushrooms, as well as fibrous material such as corn husks and sugar cane bagasse, and birch.

>

>

> Pubmed study:

>

> The osmolyte xylitol reduces the salt concentration of airway surface liquid and may enhance bacterial killing.

> Zabner J, Seiler MP, Launspach JL, Karp PH, Kearney WR, Look DC, JJ, Welsh MJ.

> Source

>

> Medical Institute, Departments of Internal Medicine, Pediatrics, and Physiology and Biophysics, and Nuclear Magnetic Resonance Facility, University of Iowa College of Medicine, Iowa City, IA 52242, USA. joseph-zabner@...

> Abstract

>

> The thin layer of airway surface liquid (ASL) contains antimicrobial substances that kill the small numbers of bacteria that are constantly being deposited in the lungs. An increase in ASL salt concentration inhibits the activity of airway antimicrobial factors and may partially explain the pathogenesis of cystic fibrosis (CF). We tested the hypothesis that an osmolyte with a low transepithelial permeability may lower the ASL salt concentration, thereby enhancing innate immunity. We found that the five-carbon sugar xylitol has a low transepithelial permeability, is poorly metabolized by several bacteria, and can lower the ASL salt concentration in both CF and non-CF airway epithelia in vitro. Furthermore, in a double-blind, randomized, crossover study, xylitol sprayed for 4 days into each nostril of normal volunteers significantly decreased the number of nasal coagulase-negative Staphylococcus compared with saline control. Xylitol may be of value in

decreasing ASL salt

concentration and enhancing the innate antimicrobial defense at the airway surface.

>

>

> >

> > I have had infections of the sinuses for so long and continue to be on antibiotics. I am now on 2. I have a biofilm that has MRSA in it. I have a poor sense of smell and have had many polyp surgeries, have had aspirin des. , on Xolair injections , zyflo, and many asthma meds , Have others had Mrsa and how did you manage with it?

> >

>

[Guest guest]

Thanks Nils. Will look into it.Sent from my iPhoneOn Jul 31, 2011, at 7:07 PM, Nils Bischoff <n_bischoff2001@...> wrote:

Hi Joan,I had during the last few infections success with 15G bactroban ointment, by adding a bit into the nasal rinse once a day and some small amount directly into the nose twice a day. Took me each time about a week to clear things and to stop any yellow discharge. The bactronban ointment I'm using is normally for wounds (external use) and burns a bit in the nose - it is not intended for the nose/ internal use - because of this it might have some health risks applying it this way and you might want to get professional advice before trying something like this. Just thought I mention it since you asked.ThanksNilsVon: joan harvey <thomyris7@...>An: samters Gesendet: Montag, den 1. August 2011, 12:26:34 UhrBetreff: Re: Re: Cant get rid of infection

This is interesting. I’ve had an H.flu infection for months, have been on 4 different antibiotics and nothing has worked. They’re supposed to be doing a test to find an antibiotic it isn’t resistant to, but so far the lab has screwed up and done the wrong test, so I’m still waiting. Has anyone had luck with antibiotics directly in the nose?On Jul 31, 2011, at 6:20 PM, wrote:

Don't know about MRSA, but I did have pseudomonas which is also extremely tenacious, and I went on IV therapy for two weeks with Ceftazidime. It seemed to do the trick. Once they put the IV in my arm, a nurse came by to show me how to give myself the meds twice a day - not too bad. Oral antibiotics frequently don't work on chronic bacteria and biofilm. This last therapy seemed to work (knock on wood) and I just had desens so hopefully I am in the clear. Ask about IV therapy.

- In samters , "damianodavid" <damianodavid@...> wrote:

>

> Have you heard of Xylitol?

> I found a study on xylitol an staph and the full text is available pubmed. Their are xylitol nasal sprays available.

>

> Web link xylitol nasal spray:

>

> http://www.xlear.com/nasal-spray.aspx

>

> From Wikipedia:

>

> Xylitol (play /?za?l?t?l/; Greek: ?????, xyl[on], "wood" + suffix -itol, used to denote sugar alcohols) is a sugar alcohol sweetener used as a naturally occurring sugar substitute. It is found in the fibers of many fruits and vegetables, and can be extracted from various berries, oats, and mushrooms, as well as fibrous material such as corn husks and sugar cane bagasse, and birch.

>

>

> Pubmed study:

>

> The osmolyte xylitol reduces the salt concentration of airway surface liquid and may enhance bacterial killing.

> Zabner J, Seiler MP, Launspach JL, Karp PH, Kearney WR, Look DC, JJ, Welsh MJ.

> Source

>

> Medical Institute, Departments of Internal Medicine, Pediatrics, and Physiology and Biophysics, and Nuclear Magnetic Resonance Facility, University of Iowa College of Medicine, Iowa City, IA 52242, USA. joseph-zabner@...

> Abstract

>

> The thin layer of airway surface liquid (ASL) contains antimicrobial substances that kill the small numbers of bacteria that are constantly being deposited in the lungs. An increase in ASL salt concentration inhibits the activity of airway antimicrobial factors and may partially explain the pathogenesis of cystic fibrosis (CF). We tested the hypothesis that an osmolyte with a low transepithelial permeability may lower the ASL salt concentration, thereby enhancing innate immunity. We found that the five-carbon sugar xylitol has a low transepithelial permeability, is poorly metabolized by several bacteria, and can lower the ASL salt concentration in both CF and non-CF airway epithelia in vitro. Furthermore, in a double-blind, randomized, crossover study, xylitol sprayed for 4 days into each nostril of normal volunteers significantly decreased the number of nasal coagulase-negative Staphylococcus compared with saline control. Xylitol may be of value in

decreasing ASL salt

concentration and enhancing the innate antimicrobial defense at the airway surface.

>

>

> >

> > I have had infections of the sinuses for so long and continue to be on antibiotics. I am now on 2. I have a biofilm that has MRSA in it. I have a poor sense of smell and have had many polyp surgeries, have had aspirin des. , on Xolair injections , zyflo, and many asthma meds , Have others had Mrsa and how did you manage with it?

> >

>