RE: Re: zyflo and aspirin?

[Guest guest]

Thanks! That's sounds about right -- i cut the zyflo dose a little yesterday and symptoms were a little worse but there was no huge jump in symptoms, which is what I feared.As far as irrigation, my hunch is that if the water manages to exit the nose, it's probably not a big deal if it's not sterile. (However, sometimes when symptoms are bad, it seems to get squirted up and go nowhere -- that's probably not that great no matter what kind of water is used) Besides, tap water has to be monitored for any significant bacteria count. Boiled or distilled is probably safer, but like you say -- would I ever bother if I had to go to all that trouble? Knowing me, probably not.

On 1/3/06, phymphya <nkrich@...> wrote:

I was on zyflo when I did the desensitization. I stayed on it forseveral weeks then I discontinued both the zyflo and singulaire. I

did note a transient increase in symptoms for a day or two. I have ahunch that you may be correct.regarding irrigation: I guess I don't worry as much about infection.I just use tap water and either the neil-med sinus pack when I use

the small bottle or two teaspoons of non-iodized salt when I use thewater pik irrigator with the sinus tip. At night, it is nice to justfill that little bottle with a packet and irrigate quickly and goback to sleep when my nose is stuffed and dried. Maybe there is an

infection risk, but I think keeping the nose open is most important.If you are immediately post-op I suspect you would want to be morecareful. If I had to do all the boiling or getting special water, Iwould never get around to irrigating the nose.

>> Hi guys,>> Wondering if anyone's taken zyflo during desensitization or onmaintenance> dose of aspirin? I desensitized myself (I know, I know..) but I'mstill on> zyflo and I wonder if the zyflo might partially block the

desensitization> effect (less available leukotrienes altogether == less down-regulation of> receptors?) I seem a little more sensitive to taking my next zyflodosage> late, which could be one indicator that such an effect is happening.

>> --> Condouris> cell 646-234-6669> land 212-459-2398> Work: http://amberdigital.com> Play:

http://wackyneighbor.com>

[Guest guest]

Wow! Today, I was getting sniffly around 6pm -- after having taken a normal and enteric 325 mg at 7am -- and it occurred to me that maybe instead of being a *delayed* reaction to aspirin, it was a reaction to having NO aspirin in my system. So I took another 325 at 7pm, after having taken a zyflo at 6, and my nose actually cleared!

Maybe it's placebo effect, but cleared nose after asprin feels a little different than the way it feels with just zyflo. It seems more like all the tissue is going down a little, rather than just the polyps backing off. I dunno if that's a good way to describe it, and maybe i'm exaggerating the effect. But I'd love to hear how people felt individual aspirin doses felt during and after desense.

On 1/4/06, Condouris <condour@...> wrote:

Thanks! That's sounds about right -- i cut the zyflo dose a little yesterday and symptoms were a little worse but there was no huge jump in symptoms, which is what I feared.As far as irrigation, my hunch is that if the water manages to exit the nose, it's probably not a big deal if it's not sterile. (However, sometimes when symptoms are bad, it seems to get squirted up and go nowhere -- that's probably not that great no matter what kind of water is used) Besides, tap water has to be monitored for any significant bacteria count. Boiled or distilled is probably safer, but like you say -- would I ever bother if I had to go to all that trouble? Knowing me, probably not.

On 1/3/06, phymphya <

nkrich@...> wrote:

I was on zyflo when I did the desensitization. I stayed on it for

several weeks then I discontinued both the zyflo and singulaire. I

did note a transient increase in symptoms for a day or two. I have ahunch that you may be correct.regarding irrigation: I guess I don't worry as much about infection.I just use tap water and either the neil-med sinus pack when I use

the small bottle or two teaspoons of non-iodized salt when I use thewater pik irrigator with the sinus tip. At night, it is nice to justfill that little bottle with a packet and irrigate quickly and goback to sleep when my nose is stuffed and dried. Maybe there is an

infection risk, but I think keeping the nose open is most important.If you are immediately post-op I suspect you would want to be morecareful. If I had to do all the boiling or getting special water, Iwould never get around to irrigating the nose.

>> Hi guys,>> Wondering if anyone's taken zyflo during desensitization or onmaintenance> dose of aspirin? I desensitized myself (I know, I know..) but I'mstill on> zyflo and I wonder if the zyflo might partially block the

desensitization> effect (less available leukotrienes altogether == less down-regulation of> receptors?) I seem a little more sensitive to taking my next zyflodosage> late, which could be one indicator that such an effect is happening.

>> --> Condouris> cell 646-234-6669> land 212-459-2398> Work: http://amberdigital.com

> Play:

http://wackyneighbor.com>

[Guest guest]

In a message dated 1/6/2006 8:52:23 A.M. US Mountain Standard Time, condour@... writes:

To clarify, on that particular day I took 975.

For what it's worth, might be related to a vascular issue, as aspirin is also a vasodilator. A couple of days ago I got out of bed and had an infrequent, but terrible rhinitis attack. Although I could have taken an Aleve, antihistamine, spray etc., I decided to lab rat it again and let it run its course rather than masking it with meds. I was shivering as my wife turned off the heat in the house and it dropped to 65 (that's cold in Arizona). After two hours, I got into my sun warmed car and my congestion cleared up within the first two miles.

Based on an earlier algorithm I pick up, I understand that if prednisone works, one can track down to three possible types of rhinitis. Infectious, allergic or irratative. My rhinitis (believe goes hand in hand with anosmia) appears to be both allergic and irritative (also called vasomotor). In my case, think I've identified most or all the allergy part but still think vascular issues are playing a role. I understand that mucous plays a protective role. It can overproduce to move allergens, viruses, dust, bacteria etc. our of the nasal area to the stomach where acid helps to obliterate the bad guys. But in the cases of vasoconstriction, it can overproduce to act as a protective barrier to the nasal membranes to keep them from drying out. I'm not sure if excess vasodilation can also cause rhinitis, or if that fast dilation is followed by some sort of fast constriction (like a rebound). I only say that because alcohol has a negative impact on some, but has been studied as a vasodilator... but may turn out to be both. Also, I understand that polyps are just tissue filled with mucous.

So, while I keep refraining from certain foods that generate low level IgE antibodies and have had good results, I'm also starting a list of stuff that causes vascular constriction.

Hope it's not just another road to nowhere. But you motivated me to take (2) coated 325mg aspirin this morning. I'll certainly try it if the heat ever goes out of this house again.

(AZ)

PS: On the food allergy side, after a lot of reflection on the very positive mental response achieved by refraining from low IgE generating foods, am starting to think the low level allergy goes back well into childhood and may even be inherited. That said, it may have just raised it's ugly head 6 years ago as rhinitis/anosmia/creeping asthma by some decrease in the efficiency of my adrenal grand (where natural corticosteroids are made), caused by excessive stress, hormones, etc.. Or not.

[Guest guest]

To clarify, on that particular day I took 975. Yesterday and today I'll be taking 1300 -- I wanted to take the last ramp-up slowly to allow my GI a little adjustment time. How long did it take you to feel improvement when you tried it?

On 1/5/06, truelori <lori@...> wrote:

,I don't think you're on a high enough dose of aspirin. The lowesteffective dose I believe was the 650 and some people needed the 1300(such as myself) to see symptom improvement. This is from the Scripps

data. I don't think 325 a day will do it.Lori

[Guest guest]

Very interesting.

My doctor has determined I definitely have irritative issues going on and probably

allergic ones. I do have a bunch of allergies (when people ask me what I am

allergic to, I tend to answer “air” as sometimes it seems that is

true!). I will know in a couple months when the grass starts to bloom if

my allergy shots are helping. I’m not convinced yet that they aren’t

making things worse as I always seem to be stuffed up after getting one. I

want to look into the food thing as I sometimes think I have food issues and

sometimes I think I don’t as they seem random almost. Though I am

noticing that right now, since I am clean from the recent surgery, foods are

not affecting me adversely. I am basing this mainly on wine consumption

and the fact that it has not stuffed me up once since surgery and before it

would completely close me up (when I was already mostly stuffed up!). Everything

for me seems to be related to my sinuses being clear. I just hope come

the worst of the allergy season I don’t stuff up and go back into the

evil cycle of stuffiness and new polyps like last year!

K.

Re: Re: zyflo

and aspirin?

In a

message dated 1/6/2006 8:52:23 A.M. US Mountain Standard Time,

condour@... writes:

To clarify, on that

particular day I took 975.

For

what it's worth, might be related to a vascular issue, as aspirin is also a

vasodilator. A couple of days ago I got out of bed and had an infrequent,

but terrible rhinitis attack. Although I could have taken an Aleve,

antihistamine, spray etc., I decided to lab rat it again and let it run its

course rather than masking it with meds. I was shivering as my wife

turned off the heat in the house and it dropped to 65 (that's cold in

Arizona). After two hours, I got into my sun warmed car and my

congestion cleared up within the first two miles.

Based

on an earlier algorithm I pick up, I understand that if prednisone works, one

can track down to three possible types of rhinitis. Infectious, allergic

or irratative. My rhinitis (believe goes hand in hand with anosmia)

appears to be both allergic and irritative (also called vasomotor). In my

case, think I've identified most or all the allergy part but still think

vascular issues are playing a role. I understand that mucous plays a

protective role. It can overproduce to move allergens, viruses, dust,

bacteria etc. our of the nasal area to the stomach where acid helps to

obliterate the bad guys. But in the cases of vasoconstriction, it can

overproduce to act as a protective barrier to the nasal membranes to keep them

from drying out. I'm not sure if excess vasodilation can also cause

rhinitis, or if that fast dilation is followed by some sort of fast

constriction (like a rebound). I only say that because alcohol has a

negative impact on some, but has been studied as a vasodilator... but

may turn out to be both. Also, I understand that polyps are just tissue

filled with mucous.

So,

while I keep refraining from certain foods that generate low level IgE

antibodies and have had good results, I'm also starting a list of stuff

that causes vascular constriction.

Hope

it's not just another road to nowhere. But you motivated me to take (2)

coated 325mg aspirin this morning. I'll certainly try it if the heat ever

goes out of this house again.

(AZ)

PS:

On the food allergy side, after a lot of reflection on the very positive mental

response achieved by refraining from low IgE generating foods, am starting to

think the low level allergy goes back well into childhood and may even be

inherited. That said, it may have just raised it's ugly head 6 years ago

as rhinitis/anosmia/creeping asthma by some decrease in the efficiency of my

adrenal grand (where natural corticosteroids are made), caused by excessive

stress, hormones, etc.. Or not.