Guest guest Posted November 3, 2007 Report Share Posted November 3, 2007  ----- Original Message ----- From: Joyce Hudson Joyce Hudson Sent: Saturday, November 03, 2007 10:31 AM Subject: Emailing: science.htm Athens/Institution Login Not Registered? User Name: Password: Remember me on this computer Forgotten password? Home Browse My Settings Alerts Help Quick Search Title, abstract, keywords Author e.g. j s smith Journal/book title Volume Issue Page Medical Hypotheses Article in Press, Corrected Proof - Note to users Abstract Full Text + Links PDF (118 K) Related Articles in ScienceDirect Databases and the future of clinical trials in bladder ...Urologic Oncology: Seminars and Original Investigations Databases and the future of clinical trials in bladder cancerUrologic Oncology: Seminars and Original Investigations, Volume 25, Issue 4, July-August 2007, Pages 330-332R. Mark Abstract As clinical trials continue to expand and evolve to include a wider range of collected information, the amount and variety of information available to clinical researchers has concurrently grown. This article describes a range of means to address this complexity and to accommodate the collection, storage, and integration of this information based on current approaches in biomedical informatics. By reviewing these current approaches, and drawing examples from actual practice within the clinical informatics community, a range of potential solutions and their potential impacts are discussed.Abstract | Full Text + Links | PDF (68 K) Raju Kucherlapati talks about personalised medicine: br...Drug Discovery Today Raju Kucherlapati talks about personalised medicine: breathing new life into old drugsDrug Discovery Today, Volume 12, Issues 7-8, April 2007, Pages 272-275Steve CarneyAbstract | Full Text + Links | PDF (109 K) Evolution of biomarkers: drug discovery to personalized...Drug Discovery Today Evolution of biomarkers: drug discovery to personalized medicineDrug Discovery Today, Volume 10, Issue 18, 15 September 2005, Pages 1216-1218Muhammad MukhtarAbstract | Full Text + Links | PDF (57 K) A new look and a heightened focus: translational medici...Journal of Laboratory and Clinical Medicine A new look and a heightened focus: translational medicine and the Journal of Laboratory and Clinical MedicineJournal of Laboratory and Clinical Medicine, Volume 144, Issue 1, July 2004, Pages 5-6Dale E. HammerschmidtAbstract | Full Text + Links | PDF (24 K) 10 Advanced data mining and predictive modelling at the...Studies in Multidisciplinarity 10 Advanced data mining and predictive modelling at the core of personalised medicineStudies in Multidisciplinarity, Volume 3, 2005, Pages 165-192Roland Somogyi, P. Mc, E. Baranzini, Parvin Mousavi and Larry D. GrellerAbstract | Abstract + References | PDF (2063 K) View More Related Articlesdoi:10.1016/j.mehy.2007.08.018 Copyright © 2007 Elsevier Ltd All rights reserved. Editorial Truly personalised medicine: Self-experimentation in medical discovery Bains, a, aRufus Scientific, 37 The Moor, Royston, Herts SG8 6ED, United Kingdom Available online 29 October 2007. Summary Biomedical research need not be carried out solely by ‘Them’: distant, dissociated, enormously costly institutions and companies. It can, and increasingly in the 21st century will, be carried out by ‘Us’, the informed non-professional. Conventional clinical trials treat humans with the same experimental model as laboratory rats – regarding them as mute, variable, unreliable material from which results must be obtained as fast as possible to maximise return on investment and patent life. The alternative is longer term, self-reported clinical studies of new treatments, based on the assumption that the experimenter is informed, intelligent and aware. A wide variety of new treatments for chronic disease are available, involving elements of diet, behaviour, environment and non-prescription medication as well as ethical pharmaceuticals, and previous experience suggests that they can be enormously effective. The key is objective, quantifiable measures of outcome. These can be achieved with over-the-counter diagnostics for a variety of parameters, as well as with self-built test systems, and careful and systematic observations of symptoms. Hypothesis generation is a key part of this process. Tel.: +44 (0)790 4931369. Note to users: The section "Articles in Press" contains peer reviewed accepted articles to be published in this journal. When the final article is assigned to an issue of the journal, the "Article in Press" version will be removed from this section and will appear in the associated published journal issue. The date it was first made available online will be carried over. Please be aware that although "Articles in Press" do not have all bibliographic details available yet, they can already be cited using the year of online publication and the DOI as follows: Author(s), Article Title, Journal (Year), DOI. Please consult the journal's reference style for the exact appearance of these elements, abbreviation of journal names and the use of punctuation. There are three types of "Articles in Press": Accepted manuscripts: these are articles that have been peer reviewed and accepted for publication by the Editorial Board. The articles have not yet been copy edited and/or formatted in the journal house style. Uncorrected proofs: these are copy edited and formatted articles that are not yet finalized and that will be corrected by the authors. Therefore the text could change before final publication. Corrected proofs: these are articles containing the authors' corrections and may, or may not yet have specific issue and page numbers assigned. Medical Hypotheses Article in Press, Corrected Proof Home Browse My Settings Alerts Help About ScienceDirect | Contact Us | Terms & Conditions | Privacy Policy Copyright © 2007 Elsevier B.V. All rights reserved. ScienceDirect® is a registered trademark of Elsevier B.V. No virus found in this incoming message.Checked by AVG Free Edition. Version: 7.5.503 / Virus Database: 269.15.20/1107 - Release Date: 11/3/2007 11:22 AM Quote Link to comment Share on other sites More sharing options...
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