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Hello everyone!

My name is Garrett and I am on this fourm on behalf of a good friend of mine who

suffers from Samter's Triad. I just wanted to get some feedback from anyone who

shares a similar situation with her, so here we go!

My friend is a 28 year old female who has had Samter's now for about six years.

It was onset (seemingly) by a nasal infection that didnt want to go away.

Asthama was also onset around the same time, maybe a bit earlier.

About two years ago it was discovered that polyps had been growing inside of her

sinus cavities. Soon after she had polyp removal surgery and all polyps were

sucessfully extracted. Witin a few months though, as all of you have probably

already guessed, the polyps returned with a vengance and her nasal tissue again

became inflamed.

Fast forward to last week. My friend had saved up what she could and was

admitted to Scripps clinic in La Jolla, CA (or Carmel Valley, I forget which) to

undergo aspirin desensitization. The procedure went sucessfully and she was

desensitized.

Before I forget I would like to also note that during this entire time period my

friend has been taking advair which has worked like a charm on her asthma; it is

a nonfactor in her life at this time. She has taken many prednisone bursts

which enable her to regain her sense of smell (which has been lost since the

beginning), taste, squashed all inflammation, released the mucus from her sinus

cavities, and allowed her to sleep a full eight to ten hours. Of course these

are short lived. Also prior to her surgery and up until the point her polyps

and nasal inflammation returned she was taking singulair 10mg as well as a nasal

steroid.

Now she is around ten days out from desensitization and her facial

pressure/nasal inflammation seems to be worse. This may be due to the fact that

her perscription for Advair and Singular had lapsed for two days and she was

unable to take them during this time.

Unfortunatly she does not have the money (or insurance I should add) to have

another polyp removal surgery.

So with all that being said, my questions are:

1) Is there anyone out there who has had sucscess (even minor) from aspirin

desensitization in combination with a leukotriene inhibitor and anything else

WITHOUT surgery?

2) Has anyone switched from Singular to Zyflo and experienced major results

(without having polyp surgery)?

3) Does anyone have any information regarding the nebulizer rinse (I have only

seen this in one topic, sorry for the ambiguity)?

4) Has anyone done any research regarding a combination aspirin desentization

and melatonin production (or inhibiting)?

Thanks in advance and it's been a pleasure to read alot of these posts.

-Garrett

PS.I typed this up pretty quick as i'm on my lunch break so please pardon the

spelling/grammar issues and any ambiguity!

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