Guest guest Posted November 1, 2010 Report Share Posted November 1, 2010 I have just been taken off Singulair by my doctor. In the last few weeks my polyps have been causing significant problems again. I am desensitized and in fact went a whole year without prednisone. Am on a heavy dose of prednisone now. I am also on Zyflo. I have had blood test for my liver to make sure that I am able to take it and will have monthly blood tests for three months. Any thoughts? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2010 Report Share Posted November 2, 2010 Why did you doctor take you off Singulair? According to my allergist, Zyflo affects the leukotriene pathway at an earlier point and is less specific than Singulair. He really wanted me to take both and said if I do decide to do aspirin desens he wants me on Zyflo while I go through the process. However, right now I only take Singulair. I tried to take the Zyflo to see if it helped, but since it has to be taken twice a day with food, I could never remember to take it and my schedule of when I took it was erratic since my meals are not always at the same time every day. I would think if your liver tests are ok, you can deal with taking it properly, and it seems to help, then stick with the Zyflo. Supposedly either it or Singulair is supposed to help those of us with Samters. K. From: samters [mailto:samters ] On Behalf Of ChartacJS@... Sent: Monday, November 01, 2010 8:45 PM samters Subject: Zyflo or Singulair? I have just been taken off Singulair by my doctor. In the last few weeks my polyps have been causing significant problems again. I am desensitized and in fact went a whole year without prednisone. Am on a heavy dose of prednisone now. I am also on Zyflo. I have had blood test for my liver to make sure that I am able to take it and will have monthly blood tests for three months. Any thoughts? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2010 Report Share Posted November 2, 2010 Hi , He didn't think that Singulair was working anymore. The following seems relevant " It is unclear whether using a drug such as an inhibitor of leukotriene production (Zyflo) is any more beneficial than using a receptor antagonist (Singulair or Accolate). Studies in asthma do not appear to favor one approach or drug over the other, and there are no data as yet to consider anything differently in the upper airway." So I am giving it a trial. Right now it's hard to see if it's working as I am having 40mg of Prednisone a day for two weeks then the taper off. I must admit the twice a day with food is a complication. Thanks for the input. Zyflo or Singulair? I have just been taken off Singulair by my doctor. In the last few weeks my polyps have been causing significant problems again. I am desensitized and in fact went a whole year without prednisone. Am on a heavy dose of prednisone now. I am also on Zyflo. I have had blood test for my liver to make sure that I am able to take it and will have monthly blood tests for three months. Any thoughts? Quote Link to comment Share on other sites More sharing options...
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