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Web Site Gives Info on Grapefruit/Drug Interactions

SUNDAY, April 17 (HealthDay News) -- As documented in a number of studies

released since the 1980s, grapefruit and grapefruit juice can dangerously

interact with common prescription medications. Now, cautionary information

about grapefruit-drug interactions is available on a Web site,

DrugInteractionCenter.org.

The site provides consumers and health professionals with a comprehensive

database of grapefruit-drug interactions. It also includes supporting

scientific literature on such interactions.

A 2002 survey found that 80 percent of doctors and more than 50 percent of

pharmacists lacked adequate information about how grapefruit juice can

affect certain drugs. Grapefruit juice is one of the most common sources of

food-drug interactions.

" Since there is a lot of inaccurate and out-of-date information on Web

sites, we developed DrugInteractionCenter.org to provide healthcare

professionals with a credible source on grapefruit-drug interactions, which

they also can recommend to interested patients, " Hartmut Derendorf,

co-director of the University of Florida's (UF) Center for Food-Drug

Interaction Research and Education, said in a prepared statement.

" Drug interactions with grapefruit are one of the most commonly

misunderstood food-drug interactions. While certain prescription drugs

interact with grapefruit juice, most do not, " said Derendorf, a professor at

UF's College of Pharmacy.

Grapefruit juice inhibits the CYP3A4 enzyme, which metabolizes certain

drugs. This interference by grapefruit juice may enhance the body's

absorption of these drugs, resulting in side effects.

More information

Here's where you can find DrugInteractionCenter.org.

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At 03:06 PM 4/17/05 -0700, you wrote:

>Web Site Gives Info on Grapefruit/Drug Interactions

,

Thanks for always being a source of good information for

the group.....I am glad that you are active on your

computer!

C.

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Hi ,

Thank you for the update on grapefruit/drug interactions. As a

person who takes medication for other medical problems, as well as

CML, I know first hand how important it is to avoid grapefruit in

any form. Thanks again for the update.

--- In , " Lieberman " <kisocean@e...>

wrote:

>

>

> Web Site Gives Info on Grapefruit/Drug Interactions

>

>

> SUNDAY, April 17 (HealthDay News) -- As documented in a number of

studies

> released since the 1980s, grapefruit and grapefruit juice can

dangerously

> interact with common prescription medications. Now, cautionary

information

> about grapefruit-drug interactions is available on a Web site,

> DrugInteractionCenter.org.

>

> The site provides consumers and health professionals with a

comprehensive

> database of grapefruit-drug interactions. It also includes

supporting

> scientific literature on such interactions.

>

> A 2002 survey found that 80 percent of doctors and more than 50

percent of

> pharmacists lacked adequate information about how grapefruit juice

can

> affect certain drugs. Grapefruit juice is one of the most common

sources of

> food-drug interactions.

>

> " Since there is a lot of inaccurate and out-of-date information on

Web

> sites, we developed DrugInteractionCenter.org to provide healthcare

> professionals with a credible source on grapefruit-drug

interactions, which

> they also can recommend to interested patients, " Hartmut Derendorf,

> co-director of the University of Florida's (UF) Center for Food-

Drug

> Interaction Research and Education, said in a prepared statement.

>

> " Drug interactions with grapefruit are one of the most commonly

> misunderstood food-drug interactions. While certain prescription

drugs

> interact with grapefruit juice, most do not, " said Derendorf, a

professor at

> UF's College of Pharmacy.

>

> Grapefruit juice inhibits the CYP3A4 enzyme, which metabolizes

certain

> drugs. This interference by grapefruit juice may enhance the body's

> absorption of these drugs, resulting in side effects.

>

> More information

>

> Here's where you can find DrugInteractionCenter.org.

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